BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 8411011)

  • 1. Inhibitors of acyl-CoA:cholesterol acyltransferase. 5. Identification and structure-activity relationships of novel beta-ketoamides as hypocholesterolemic agents.
    Augelli-Szafran CE; Blankley CJ; Roth BD; Trivedi BK; Bousley RF; Essenburg AD; Hamelehle KL; Krause BR; Stanfield RL
    J Med Chem; 1993 Oct; 36(20):2943-9. PubMed ID: 8411011
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Bioisosterism in drug design: identification of and structure-activity relationships in a series of glycine anilide ACAT inhibitors.
    Roark WH; Padia J; Bolton GL; Blankley CJ; Essenburg AD; Stanfield RL; Bousley RF; Krause BR; Roth BD
    Bioorg Med Chem; 1995 Jan; 3(1):29-39. PubMed ID: 8612044
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibitors of acyl-CoA:cholesterol acyltransferase (ACAT). 7. Development of a series of substituted N-phenyl-N'-[(1-phenylcyclopentyl)methyl]ureas with enhanced hypocholesterolemic activity.
    Trivedi BK; Purchase TS; Holmes A; Augelli-Szafran CE; Essenburg AD; Hamelehle KL; Stanfield RL; Bousley RF; Krause BR
    J Med Chem; 1994 May; 37(11):1652-9. PubMed ID: 8201599
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibitors of acyl-CoA:cholesterol O-acyltransferase. 2. Identification and structure-activity relationships of a novel series of N-alkyl-N-(heteroaryl-substituted benzyl)-N'-arylureas.
    Tanaka A; Terasawa T; Hagihara H; Sakuma Y; Ishibe N; Sawada M; Takasugi H; Tanaka H
    J Med Chem; 1998 Jun; 41(13):2390-410. PubMed ID: 9632372
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibitors of acyl-CoA:cholesterol O-acyltransferase. synthesis and pharmacological activity of (+/-)-2-dodecyl-alpha-phenyl-N-(2,4,6-trimethoxyphenyl)-2H-tetrazole-5- acetamide and structurally related tetrazole amide derivatives.
    O'Brien PM; Sliskovic DR; Picard JA; Lee HT; Purchase CF; Roth BD; White AD; Anderson M; Mueller SB; Bocan T; Bousley R; Hamelehle KL; Homan R; Lee P; Krause BR; Reindel JF; Stanfield RL; Turluck D
    J Med Chem; 1996 Jun; 39(12):2354-66. PubMed ID: 8691430
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibitors of acyl-CoA:cholesterol acyltransferase (ACAT). 2. Modification of fatty acid anilide ACAT inhibitors: bioisosteric replacement of the amide bond.
    Roark WH; Roth BD; Holmes A; Trivedi BK; Kieft KA; Essenburg AD; Krause BR; Stanfield RL
    J Med Chem; 1993 May; 36(11):1662-8. PubMed ID: 8496932
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Polyunsaturated fatty acid anilides as inhibitors of acyl-coA: cholesterol acyltransferase (ACAT).
    Matsuyama N; Kosaka T; Fukuhara M; Soda Y; Mizuno K
    Bioorg Med Chem Lett; 1999 Jul; 9(14):2039-42. PubMed ID: 10450977
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibitors of acyl-CoA:cholesterol O-acyltransferase (ACAT) as hypocholesterolemic agents: synthesis and structure-activity relationships of novel series of sulfonamides, acylphosphonamides and acylphosphoramidates.
    Lee HT; Roark WH; Picard JA; Sliskovic DR; Roth BD; Stanfield RL; Hamelehle KL; Bousley RF; Krause BR
    Bioorg Med Chem Lett; 1998 Feb; 8(3):289-94. PubMed ID: 9871672
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibitors of acyl-CoA:cholesterol O-acyltransferase (ACAT). Part 1: identification and structure-activity relationships of a novel series of substituted N-alkyl-N-biphenylylmethyl-N'-arylureas.
    Tanaka A; Terasawa T; Hagihara H; Sakuma Y; Ishibe N; Sawada M; Takasugi H; Tanaka H
    Bioorg Med Chem; 1998 Jan; 6(1):15-30. PubMed ID: 9502102
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel acyl-CoA:cholesterol acyltransferase inhibitors. Synthesis and biological activity of 3-quinolylurea derivatives.
    Tawada H; Harcourt M; Kawamura N; Kajino M; Ishikawa E; Sugiyama Y; Ikeda H; Meguro K
    J Med Chem; 1994 Jun; 37(13):2079-84. PubMed ID: 8027989
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Acyl-CoA:cholesterol O-acyl transferase (ACAT) inhibitors. 1. 2-(Alkylthio)-4,5-diphenyl-1H-imidazoles as potent inhibitors of ACAT.
    Harris NV; Smith C; Ashton MJ; Bridge AW; Bush RC; Coffee EC; Dron DI; Harper MF; Lythgoe DJ; Newton CG
    J Med Chem; 1992 Nov; 35(23):4384-92. PubMed ID: 1447739
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-activity relationships of N-(3,5-dimethoxy-4-n-octyloxycinnamoyl)-N'-(3,4-dimethylphenyl)piperazine and analogues as inhibitors of acyl-CoA: cholesterol O-acyltransferase.
    Ohishi K; Aiyama R; Hatano H; Yoshida Y; Wada Y; Yokoi W; Sawada H; Watanabe T; Yokokura T
    Chem Pharm Bull (Tokyo); 2001 Jul; 49(7):830-9. PubMed ID: 11456087
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure-activity relationship of a series of phenylureas linked to 4-phenylimidazole. Novel potent inhibitors of acyl-CoA:cholesterol O-acyltransferase with antiatherosclerotic activity. 2.
    Kimura T; Watanabe N; Matsui M; Hayashi K; Tanaka H; Ohtsuka I; Saeki T; Kogushi M; Kabayashi H; Akasaka K
    J Med Chem; 1993 May; 36(11):1641-53. PubMed ID: 8496931
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Relationships between lipophilicity and biological activities in a series of indoline-based anti-oxidative acyl-CoA:cholesterol acyltransferase (ACAT) inhibitors.
    Takahashi K; Kunishiro K; Kasai M; Miike T; Kurahashi K; Shirahase H
    Arzneimittelforschung; 2008; 58(12):666-72. PubMed ID: 19202739
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibitors of acyl-CoA:cholesterol acyltransferase. 1. Identification and structure-activity relationships of a novel series of fatty acid anilide hypocholesterolemic agents.
    Roth BD; Blankley CJ; Hoefle ML; Holmes A; Roark WH; Trivedi BK; Essenburg AD; Kieft KA; Krause BR; Stanfield RL
    J Med Chem; 1992 May; 35(9):1609-17. PubMed ID: 1578488
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmacological profile of F 12511, (S)-2',3', 5'-trimethyl-4'-hydroxy-alpha-dodecylthioacetanilide a powerful and systemic acylcoenzyme A: cholesterol acyltransferase inhibitor.
    Junquero D; Oms P; Carilla-Durand E; Autin J; Tarayre J; Degryse A; Patoiseau J; Colpaert FC; Delhon A
    Biochem Pharmacol; 2001 Jan; 61(1):97-108. PubMed ID: 11137714
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibitors of acyl-CoA: cholesterol acyltransferase. II. Preparation and hypocholesterolemic activity of optically active dibenz[b,e]oxepin-11-carboxanilides.
    Kumazawa T; Yanase M; Shirakura S; Ohishi E; Yamada K; Matsumiya S; Kono M
    Chem Pharm Bull (Tokyo); 1996 Jan; 44(1):222-5. PubMed ID: 8582041
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibitors of acyl-CoA:cholesterol acyltransferase: novel trisubstituted ureas as hypocholesterolemic agents.
    Purchase TS; Essenburg AD; Hamelehle KL; Hes MS; Holmes A; Krause BR; Stanfield RL; Trivedi BK
    Bioorg Med Chem; 1997 Apr; 5(4):739-47. PubMed ID: 9158873
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibitors of acyl-CoA:cholesterol acyltransferase. 1. Synthesis and hypocholesterolemic activity of dibenz[b,e]oxepin-11-carboxanilides.
    Kumazawa T; Yanase M; Harakawa H; Obase H; Shirakura S; Ohishi E; Oda S; Kubo K; Yamada K
    J Med Chem; 1994 Mar; 37(6):804-10. PubMed ID: 8145231
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Plasma cholesterol reducing effect of FR129169, a novel acyl-CoA:cholesterol acyltransferase inhibitor, in the rat.
    Sakuma Y; Hagihara H; Ohne K; Nagayoshi A; Mutoh S; Ito Y; Notsu Y; Okuhara M
    Jpn J Pharmacol; 1996 Jan; 70(1):35-41. PubMed ID: 8822087
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.