487 related articles for article (PubMed ID: 8423554)
1. Species differences in stereoselective metabolism of mephenytoin by cytochrome P450 (CYP2C and CYP3A).
Yasumori T; Chen L; Nagata K; Yamazoe Y; Kato R
J Pharmacol Exp Ther; 1993 Jan; 264(1):89-94. PubMed ID: 8423554
[TBL] [Abstract][Full Text] [Related]
2. Characterization of monkey cytochrome P450, P450 CMLd, responsible for S-mephenytoin 4-hydroxylation in hepatic microsomes of cynomolgus monkeys.
Ohmori S; Chiba K; Nakasa H; Horie T; Kitada M
Arch Biochem Biophys; 1994 Jun; 311(2):395-401. PubMed ID: 8203903
[TBL] [Abstract][Full Text] [Related]
3. Lack of low Km diazepam N-demethylase in livers of poor metabolizers for S-mephenytoin 4'-hydroxylation.
Yasumori T; Li QH; Yamazoe Y; Ueda M; Tsuzuki T; Kato R
Pharmacogenetics; 1994 Dec; 4(6):323-31. PubMed ID: 7704038
[TBL] [Abstract][Full Text] [Related]
4. Catalytic role of cytochrome P4502B6 in the N-demethylation of S-mephenytoin.
Heyn H; White RB; Stevens JC
Drug Metab Dispos; 1996 Sep; 24(9):948-54. PubMed ID: 8886603
[TBL] [Abstract][Full Text] [Related]
5. Characterization of CYP2C19 and CYP2C9 from human liver: respective roles in microsomal tolbutamide, S-mephenytoin, and omeprazole hydroxylations.
Lasker JM; Wester MR; Aramsombatdee E; Raucy JL
Arch Biochem Biophys; 1998 May; 353(1):16-28. PubMed ID: 9578596
[TBL] [Abstract][Full Text] [Related]
6. CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes.
Ramírez J; Innocenti F; Schuetz EG; Flockhart DA; Relling MV; Santucci R; Ratain MJ
Drug Metab Dispos; 2004 Sep; 32(9):930-6. PubMed ID: 15319333
[TBL] [Abstract][Full Text] [Related]
7. CYP2C19 participates in tolbutamide hydroxylation by human liver microsomes.
Wester MR; Lasker JM; Johnson EF; Raucy JL
Drug Metab Dispos; 2000 Mar; 28(3):354-9. PubMed ID: 10681382
[TBL] [Abstract][Full Text] [Related]
8. Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A.
Niwa T; Shiraga T; Mitani Y; Terakawa M; Tokuma Y; Kagayama A
Drug Metab Dispos; 2000 Sep; 28(9):1128-34. PubMed ID: 10950860
[TBL] [Abstract][Full Text] [Related]
9. Role of CYP2C19 in stereoselective hydroxylation of mephobarbital by human liver microsomes.
Kobayashi K; Kogo M; Tani M; Shimada N; Ishizaki T; Numazawa S; Yoshida T; Yamamoto T; Kuroiwa Y; Chiba K
Drug Metab Dispos; 2001 Jan; 29(1):36-40. PubMed ID: 11124227
[TBL] [Abstract][Full Text] [Related]
10. Participation of a rat liver cytochrome P-450 induced by pregnenolone 16 alpha-carbonitrile and other compounds in the 4-hydroxylation of mephenytoin.
Shimada T; Guengerich FP
Mol Pharmacol; 1985 Aug; 28(2):215-9. PubMed ID: 4022003
[TBL] [Abstract][Full Text] [Related]
11. Metabolism of tauromustine in liver and lung microsomes from various species.
Tuvesson H; Gunnarsson PO; Seidegård J
Xenobiotica; 1999 Aug; 29(8):783-92. PubMed ID: 10553719
[TBL] [Abstract][Full Text] [Related]
12. 5-hydroxylation of omeprazole by human liver microsomal fractions from Chinese populations related to CYP2C19 gene dose and individual ethnicity.
Shu Y; Wang LS; Xu ZH; He N; Xiao WM; Wang W; Huang SL; Zhou HH
J Pharmacol Exp Ther; 2000 Nov; 295(2):844-51. PubMed ID: 11046127
[TBL] [Abstract][Full Text] [Related]
13. Human liver microsomal cytochrome P-450 mephenytoin 4-hydroxylase, a prototype of genetic polymorphism in oxidative drug metabolism. Purification and characterization of two similar forms involved in the reaction.
Shimada T; Misono KS; Guengerich FP
J Biol Chem; 1986 Jan; 261(2):909-21. PubMed ID: 3079764
[TBL] [Abstract][Full Text] [Related]
14. mRNA and protein expression of dog liver cytochromes P450 in relation to the metabolism of human CYP2C substrates.
Graham MJ; Bell AR; Crewe HK; Moorcraft CL; Walker L; Whittaker EF; Lennard MS
Xenobiotica; 2003 Mar; 33(3):225-37. PubMed ID: 12637241
[TBL] [Abstract][Full Text] [Related]
15. Identification of cytochrome P450 isoforms involved in citalopram N-demethylation by human liver microsomes.
Kobayashi K; Chiba K; Yagi T; Shimada N; Taniguchi T; Horie T; Tani M; Yamamoto T; Ishizaki T; Kuroiwa Y
J Pharmacol Exp Ther; 1997 Feb; 280(2):927-33. PubMed ID: 9023308
[TBL] [Abstract][Full Text] [Related]
16. Formation of (R)-8-hydroxywarfarin in human liver microsomes. A new metabolic marker for the (S)-mephenytoin hydroxylase, P4502C19.
Wienkers LC; Wurden CJ; Storch E; Kunze KL; Rettie AE; Trager WF
Drug Metab Dispos; 1996 May; 24(5):610-4. PubMed ID: 8723744
[TBL] [Abstract][Full Text] [Related]
17. Stereoselective metabolism of ifosfamide by human P-450s 3A4 and 2B6. Favorable metabolic properties of R-enantiomer.
Roy P; Tretyakov O; Wright J; Waxman DJ
Drug Metab Dispos; 1999 Nov; 27(11):1309-18. PubMed ID: 10534317
[TBL] [Abstract][Full Text] [Related]
18. Role of CYP2B6 and CYP3A4 in the in vitro N-dechloroethylation of (R)- and (S)-ifosfamide in human liver microsomes.
Granvil CP; Madan A; Sharkawi M; Parkinson A; Wainer IW
Drug Metab Dispos; 1999 Apr; 27(4):533-41. PubMed ID: 10101149
[TBL] [Abstract][Full Text] [Related]
19. Human CYP2C19 is a major omeprazole 5-hydroxylase, as demonstrated with recombinant cytochrome P450 enzymes.
Karam WG; Goldstein JA; Lasker JM; Ghanayem BI
Drug Metab Dispos; 1996 Oct; 24(10):1081-7. PubMed ID: 8894508
[TBL] [Abstract][Full Text] [Related]
20. Human CYP2C-mediated stereoselective phenytoin hydroxylation in Japanese: difference in chiral preference of CYP2C9 and CYP2C19.
Yasumori T; Chen LS; Li QH; Ueda M; Tsuzuki T; Goldstein JA; Kato R; Yamazoe Y
Biochem Pharmacol; 1999 Jun; 57(11):1297-303. PubMed ID: 10230773
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
