BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

413 related articles for article (PubMed ID: 8424816)

  • 1. Sensitivity of aldehyde dehydrogenases in murine tumor and hematopoietic progenitor cells to inhibition by chloral hydrate as determined by the ability of chloral hydrate to potentiate the cytotoxic action of mafosfamide.
    Maki PA; Sladek NE
    Biochem Pharmacol; 1993 Jan; 45(1):231-9. PubMed ID: 8424816
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Potentiation of the cytotoxic action of mafosfamide by N-isopropyl-p-formylbenzamide, a metabolite of procarbazine.
    Maki PA; Sladek NE
    Cancer Res; 1991 Aug; 51(16):4170-5. PubMed ID: 1868438
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effects of aldehyde dehydrogenase inhibitors on the ex vivo sensitivity of murine late spleen colony-forming cells (day-12 CFU-S) and hematopoietic repopulating cells to mafosfamide (ASTA Z 7557).
    Kohn FR; Sladek NE
    Biochem Pharmacol; 1987 Sep; 36(17):2805-11. PubMed ID: 2820422
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Aldehyde dehydrogenase activity as the basis for the relative insensitivity of murine pluripotent hematopoietic stem cells to oxazaphosphorines.
    Kohn FR; Sladek NE
    Biochem Pharmacol; 1985 Oct; 34(19):3465-71. PubMed ID: 2996550
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effect of aldehyde dehydrogenase inhibitors on the ex vivo sensitivity of human multipotent and committed hematopoietic progenitor cells and malignant blood cells to oxazaphosphorines.
    Kohn FR; Landkamer GJ; Manthey CL; Ramsay NK; Sladek NE
    Cancer Res; 1987 Jun; 47(12):3180-5. PubMed ID: 3034402
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effect of the aldehyde dehydrogenase inhibitor, cyanamide, on the ex vivo sensitivity of murine multipotent and committed hematopoietic progenitor cells to mafosfamide (ASTA Z 7557).
    Kohn FR; Landkamer GJ; Sladek NE
    Immunopharmacol Immunotoxicol; 1987; 9(2-3):163-76. PubMed ID: 3437102
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Restoration of sensitivity to oxazaphosphorines by inhibitors of aldehyde dehydrogenase activity in cultured oxazaphosphorine-resistant L1210 and cross-linking agent-resistant P388 cell lines.
    Sladek NE; Landkamer GJ
    Cancer Res; 1985 Apr; 45(4):1549-55. PubMed ID: 3978623
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Intrinsic cellular resistance to oxazaphosphorines exhibited by a human colon carcinoma cell line expressing relatively large amounts of a class-3 aldehyde dehydrogenase.
    Rekha GK; Sreerama L; Sladek NE
    Biochem Pharmacol; 1994 Nov; 48(10):1943-52. PubMed ID: 7986206
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of the mouse aldehyde dehydrogenases important in aldophosphamide detoxification.
    Manthey CL; Landkamer GJ; Sladek NE
    Cancer Res; 1990 Aug; 50(16):4991-5002. PubMed ID: 2379164
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of a methylcholanthrene-induced aldehyde dehydrogenase in a human breast adenocarcinoma cell line exhibiting oxazaphosphorine-specific acquired resistance.
    Sreerama L; Sladek NE
    Cancer Res; 1994 Apr; 54(8):2176-85. PubMed ID: 8174125
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of human liver aldehyde dehydrogenases that catalyze the oxidation of aldophosphamide and retinaldehyde.
    Dockham PA; Lee MO; Sladek NE
    Biochem Pharmacol; 1992 Jun; 43(11):2453-69. PubMed ID: 1610409
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human breast adenocarcinoma MCF-7/0 cells electroporated with cytosolic class 3 aldehyde dehydrogenases obtained from tumor cells and a normal tissue exhibit differential sensitivity to mafosfamide.
    Sreerama L; Sladek NE
    Drug Metab Dispos; 1995 Oct; 23(10):1080-4. PubMed ID: 8654195
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential sensitivity of adherent CFU-blast, CFU-mix, BFU-E, and CFU-GM to mafosfamide: implications for adjusted dose purging in autologous bone marrow transplantation.
    Carlo-Stella C; Mangoni L; Almici C; Garau D; Craviotto L; Piovani G; Caramatti C; Rizzoli V
    Exp Hematol; 1992 Mar; 20(3):328-33. PubMed ID: 1568448
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of recombinant human stem cell factor on mafosfamide-treated bone marrow clonogenic cells.
    Carlo-Stella C; Mangoni L; Almici C; Caramatti C; Rizzoli V
    Stem Cells; 1993 Jul; 11 Suppl 2():170-4. PubMed ID: 7691323
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inactivation of aldophosphamide by human aldehyde dehydrogenase isozyme 3.
    Giorgianni F; Bridson PK; Sorrentino BP; Pohl J; Blakley RL
    Biochem Pharmacol; 2000 Aug; 60(3):325-38. PubMed ID: 10856427
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Aldehyde dehydrogenase-mediated cellular relative insensitivity to the oxazaphosphorines.
    Sládek NE
    Curr Pharm Des; 1999 Aug; 5(8):607-25. PubMed ID: 10469894
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Oxazaphosphorine-specific resistance in human MCF-7 breast carcinoma cell lines expressing transfected rat class 3 aldehyde dehydrogenase.
    Bunting KD; Lindahl R; Townsend AJ
    J Biol Chem; 1994 Sep; 269(37):23197-203. PubMed ID: 8083225
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Development of selective inhibitors for human aldehyde dehydrogenase 3A1 (ALDH3A1) for the enhancement of cyclophosphamide cytotoxicity.
    Parajuli B; Georgiadis TM; Fishel ML; Hurley TD
    Chembiochem; 2014 Mar; 15(5):701-12. PubMed ID: 24677340
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Metabolism and transport of oxazaphosphorines and the clinical implications.
    Zhang J; Tian Q; Yung Chan S; Chuen Li S; Zhou S; Duan W; Zhu YZ
    Drug Metab Rev; 2005; 37(4):611-703. PubMed ID: 16393888
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Protection by transfected rat or human class 3 aldehyde dehydrogenase against the cytotoxic effects of oxazaphosphorine alkylating agents in hamster V79 cell lines. Demonstration of aldophosphamide metabolism by the human cytosolic class 3 isozyme.
    Bunting KD; Townsend AJ
    J Biol Chem; 1996 May; 271(20):11891-6. PubMed ID: 8662659
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.