These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

109 related articles for article (PubMed ID: 8427581)

  • 1. DNA binding and cleavage of a novel antitumor antibiotic dynemicin A: detection of binding and cleavage sites by exonuclease III digestion and alkali-induced cutting reactions.
    Arakawa T; Kusakabe T; Kuwahara J; Otsuka M; Sugiura Y
    Biochem Biophys Res Commun; 1993 Jan; 190(2):362-70. PubMed ID: 8427581
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Site-specific interaction of the antitumor antibiotic dynemicin with branched DNA molecules.
    Lu M; Guo Q; Kallenbach NR
    J Biomol Struct Dyn; 1991 Oct; 9(2):271-83. PubMed ID: 1741963
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Visible light induced DNA cleavage by the hybrid antitumor antibiotic dynemicin A.
    Shiraki T; Sugiura Y
    Biochemistry; 1990 Oct; 29(42):9795-8. PubMed ID: 2271616
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A model for the dynemicin-A cleavage of DNA using molecular dynamics simulation.
    Cardozo MG; Hopfinger AJ
    Biopolymers; 1993 Mar; 33(3):377-88. PubMed ID: 8461449
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sequence preference for strand cleavage of gapped duplexes by dynemicin A: possible mechanism of sequence-dependent double-stranded breaks.
    Kusakabe T; Uesugi M; Sugiura Y
    Biochemistry; 1995 Aug; 34(31):9944-50. PubMed ID: 7632693
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DNA intercalation and cleavage of an antitumor antibiotic dynemicin that contains anthracycline and enediyne cores.
    Sugiura Y; Shiraki T; Konishi M; Oki T
    Proc Natl Acad Sci U S A; 1990 May; 87(10):3831-5. PubMed ID: 2339123
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Enzymatic activation of DNA cleavage by dynemicin A and synthetic analogs.
    Myers AG; Kort ME; Cohen SB; Tom NJ
    Biochemistry; 1997 Apr; 36(13):3903-8. PubMed ID: 9092820
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Solution structure of the calicheamicin gamma 1I-DNA complex.
    Kumar RA; Ikemoto N; Patel DJ
    J Mol Biol; 1997 Jan; 265(2):187-201. PubMed ID: 9020982
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Conformation-selective DNA strand breaks by dynemicin: a molecular wedge into flexible regions of DNA.
    Kusakabe T; Maekawa K; Ichikawa A; Uesugi M; Sugiura Y
    Biochemistry; 1993 Nov; 32(43):11669-75. PubMed ID: 8218234
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cytotoxicity and DNA-binding property of non-diynene class of dynemicins and aza-anthraquinones.
    Shirai R; Shimazawa R; Shichita M; Takahashi M; Hashimoto Y; Iwasaki S
    Nucleic Acids Symp Ser; 1995; (34):151-2. PubMed ID: 8841597
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Reductive and nucleophilic activation products of dynemicin A with methyl thioglycolate. A rational mechanism for DNA cleavage of the thiol-activated dynemicin A.
    Sugiura Y; Arakawa T; Uesugi M; Shiraki T; Ohkuma H; Konishi M
    Biochemistry; 1991 Mar; 30(12):2989-92. PubMed ID: 2007134
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular mechanics and molecular dynamics studies of the intercalation of dynemicin-A with oligonucleotide models of DNA.
    Cardozo MG; Hopfinger AJ
    Mol Pharmacol; 1991 Dec; 40(6):1023-8. PubMed ID: 1758437
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DNA binding and cleavage by enediyne antitumor antibiotics, esperamicin and dynemicin.
    Shiraki T; Sugiura Y
    Nucleic Acids Symp Ser; 1989; (21):53-4. PubMed ID: 2608476
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Docking, triggering, and biological activity of dynemicin A in DNA: a computational study.
    Tuttle T; Kraka E; Cremer D
    J Am Chem Soc; 2005 Jul; 127(26):9469-84. PubMed ID: 15984874
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design of a new warhead for the natural enediyne dynemicin A. An increase of biological activity.
    Kraka E; Tuttle T; Cremer D
    J Phys Chem B; 2008 Mar; 112(9):2661-70. PubMed ID: 18269275
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Studies on DNA-cleaving agents: computer modeling analysis of the mechanism of activation and cleavage of dynemicin-oligonucleotide complexes.
    Wender PA; Kelly RC; Beckham S; Miller BL
    Proc Natl Acad Sci U S A; 1991 Oct; 88(19):8835-9. PubMed ID: 1924343
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation of DNA cleavage by dynemicin A in a B-Z conformational junction.
    Ichikawa A; Kuboya T; Aoyama T; Sugiura Y
    Biochemistry; 1992 Jul; 31(29):6784-7. PubMed ID: 1379070
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis of (+)-dynemicin A and analogs of wide structural variability: establishment of the absolute configuration of natural dynemicin A.
    Myers AG; Fraley ME; Tom NJ; Cohen SB; Madar DJ
    Chem Biol; 1995 Jan; 2(1):33-43. PubMed ID: 9383401
    [TBL] [Abstract][Full Text] [Related]  

  • 19. C-1' hydrogen abstraction of deoxyribose in DNA strand scission by dynemicin A.
    Shiraki T; Uesugi M; Sugiura Y
    Biochem Biophys Res Commun; 1992 Oct; 188(2):584-9. PubMed ID: 1280117
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Internal abstraction of dynemicin A: An MD approach.
    Beane A; Miller BR; Parish CA
    J Mol Graph Model; 2017 Jun; 74():251-264. PubMed ID: 28458004
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.