180 related articles for article (PubMed ID: 8428358)
1. Two types of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone hemoglobin adducts, from metabolites which migrate into or are formed in red blood cells.
Murphy SE; Coletta KA
Cancer Res; 1993 Feb; 53(4):777-83. PubMed ID: 8428358
[TBL] [Abstract][Full Text] [Related]
2. Evaluation of cysteine adduct formation in rat hemoglobin by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and related compounds.
Carmella SG; Kagan SS; Spratt TE; Hecht SS
Cancer Res; 1990 Sep; 50(17):5453-9. PubMed ID: 2201436
[TBL] [Abstract][Full Text] [Related]
3. Formation of hemoglobin adducts upon treatment of F344 rats with the tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N'-nitrosonornicotine.
Carmella SG; Hecht SS
Cancer Res; 1987 May; 47(10):2626-30. PubMed ID: 3567895
[TBL] [Abstract][Full Text] [Related]
4. Comparative metabolism of N'-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by cultured F344 rat oral tissue and esophagus.
Murphy SE; Heiblum R; Trushin N
Cancer Res; 1990 Aug; 50(15):4685-91. PubMed ID: 2369743
[TBL] [Abstract][Full Text] [Related]
5. The pyridyloxobutyl DNA adduct, O6-[4-oxo-4-(3-pyridyl)butyl]guanine, is detected in tissues from 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-treated A/J mice.
Thomson NM; Kenney PM; Peterson LA
Chem Res Toxicol; 2003 Jan; 16(1):1-6. PubMed ID: 12693024
[TBL] [Abstract][Full Text] [Related]
6. Quantitation of pyridylhydroxybutyl-DNA adducts in liver and lung of F-344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
Upadhyaya P; Kalscheuer S; Hochalter JB; Villalta PW; Hecht SS
Chem Res Toxicol; 2008 Jul; 21(7):1468-76. PubMed ID: 18570389
[TBL] [Abstract][Full Text] [Related]
7. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in isolated rat lung and liver.
Schrader E; Hirsch-Ernst KI; Richter E; Foth H
Naunyn Schmiedebergs Arch Pharmacol; 1998 Mar; 357(3):336-43. PubMed ID: 9550307
[TBL] [Abstract][Full Text] [Related]
8. Dose-response study of DNA and hemoglobin adduct formation by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in F344 rats.
Murphy SE; Palomino A; Hecht SS; Hoffmann D
Cancer Res; 1990 Sep; 50(17):5446-52. PubMed ID: 2386949
[TBL] [Abstract][Full Text] [Related]
9. Metabolism and DNA single strand breaks induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its analogues in primary culture of rat hepatocytes.
Liu LL; Alaoui-Jamali MA; el Alami N; Castonguay A
Cancer Res; 1990 Mar; 50(6):1810-6. PubMed ID: 2306734
[TBL] [Abstract][Full Text] [Related]
10. Effects of phenobarbital and 3-methylcholanthrene induction on the formation of three glucuronide metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, NNK.
Murphy SE; Nunes MG; Hatala MA
Chem Biol Interact; 1997 Mar; 103(3):153-66. PubMed ID: 9134006
[TBL] [Abstract][Full Text] [Related]
11. Methyl DNA Phosphate Adduct Formation in Rats Treated Chronically with 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Enantiomers of Its Metabolite 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol.
Ma B; Zarth AT; Carlson ES; Villalta PW; Upadhyaya P; Stepanov I; Hecht SS
Chem Res Toxicol; 2018 Jan; 31(1):48-57. PubMed ID: 29131934
[TBL] [Abstract][Full Text] [Related]
12. Glucuronidation of 4-((hydroxymethyl)nitrosamino)-1-(3-pyridyl)-1-butanone, a metabolically activated form of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, by phenobarbital-treated rats.
Murphy SE; Spina DA; Nunes MG; Pullo DA
Chem Res Toxicol; 1995; 8(5):772-9. PubMed ID: 7548761
[TBL] [Abstract][Full Text] [Related]
13. Investigations of metabolic precursors to hemoglobin and DNA adducts of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
Peterson LA; Carmella SG; Hecht SS
Carcinogenesis; 1990 Aug; 11(8):1329-33. PubMed ID: 2387018
[TBL] [Abstract][Full Text] [Related]
14. Mass spectrometric analysis of relative levels of pyridyloxobutylation adducts formed in the reaction of DNA with a chemically activated form of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
Sturla SJ; Scott J; Lao Y; Hecht SS; Villalta PW
Chem Res Toxicol; 2005 Jun; 18(6):1048-55. PubMed ID: 15962940
[TBL] [Abstract][Full Text] [Related]
15. Evidence that a hemoglobin adduct of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone is a 4-(3-pyridyl)-4-oxobutyl carboxylic acid ester.
Carmella SG; Kagan SS; Hecht SS
Chem Res Toxicol; 1992; 5(1):76-80. PubMed ID: 1581541
[TBL] [Abstract][Full Text] [Related]
16. Effects of benzyl isothiocyanate and 2-phenethyl isothiocyanate on benzo[a]pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism in F-344 rats.
Boysen G; Kenney PM; Upadhyaya P; Wang M; Hecht SS
Carcinogenesis; 2003 Mar; 24(3):517-25. PubMed ID: 12663513
[TBL] [Abstract][Full Text] [Related]
17. Quantitation of microsomal alpha-hydroxylation of the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
Peterson LA; Mathew R; Hecht SS
Cancer Res; 1991 Oct; 51(20):5495-500. PubMed ID: 1913670
[TBL] [Abstract][Full Text] [Related]
18. Stereoselective metabolism of nicotine and tobacco-specific N-nitrosamines to 4-hydroxy-4-(3-pyridyl)butanoic acid in rats.
Trushin N; Hecht SS
Chem Res Toxicol; 1999 Feb; 12(2):164-71. PubMed ID: 10027794
[TBL] [Abstract][Full Text] [Related]
19. Complete inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced rat lung tumorigenesis and favorable modification of biomarkers by phenethyl isothiocyanate.
Hecht SS; Trushin N; Rigotty J; Carmella SG; Borukhova A; Akerkar S; Rivenson A
Cancer Epidemiol Biomarkers Prev; 1996 Aug; 5(8):645-52. PubMed ID: 8824368
[TBL] [Abstract][Full Text] [Related]
20. Cell specificity for the pulmonary metabolism of tobacco-specific nitrosamines in the Fischer rat.
Belinsky SA; White CM; Trushin N; Hecht SS
Carcinogenesis; 1989 Dec; 10(12):2269-74. PubMed ID: 2591016
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]