These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

117 related articles for article (PubMed ID: 8428981)

  • 1. Interactions of a hybrid insulin/insulin-like growth factor-I analog with chimeric insulin/type I insulin-like growth factor receptors.
    Schäffer L; Kjeldsen T; Andersen AS; Wiberg FC; Larsen UD; Cara JF; Mirmira RG; Nakagawa SH; Tager HS
    J Biol Chem; 1993 Feb; 268(5):3044-7. PubMed ID: 8428981
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A single-chain insulin-like growth factor I/insulin hybrid binds with high affinity to the insulin receptor.
    Kristensen C; Andersen AS; Hach M; Wiberg FC; Schäffer L; Kjeldsen T
    Biochem J; 1995 Feb; 305 ( Pt 3)(Pt 3):981-6. PubMed ID: 7848300
    [TBL] [Abstract][Full Text] [Related]  

  • 3. An insulin-like growth factor I/insulin hybrid exhibiting high potency for interaction with the type I insulin-like growth factor and insulin receptors of placental plasma membranes.
    Cara JF; Mirmira RG; Nakagawa SH; Tager HS
    J Biol Chem; 1990 Oct; 265(29):17820-5. PubMed ID: 2170397
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hybrid receptors formed by insulin receptor (IR) and insulin-like growth factor I receptor (IGF-IR) have low insulin and high IGF-1 affinity irrespective of the IR splice variant.
    Slaaby R; Schäffer L; Lautrup-Larsen I; Andersen AS; Shaw AC; Mathiasen IS; Brandt J
    J Biol Chem; 2006 Sep; 281(36):25869-74. PubMed ID: 16831875
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Relationship between alpha subunit ligand occupancy and beta subunit autophosphorylation in insulin/insulin-like growth factor-1 hybrid receptors.
    Frattali AL; Pessin JE
    J Biol Chem; 1993 Apr; 268(10):7393-400. PubMed ID: 8463272
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An investigation of the ligand binding properties and negative cooperativity of soluble insulin-like growth factor receptors.
    Surinya KH; Forbes BE; Occhiodoro F; Booker GW; Francis GL; Siddle K; Wallace JC; Cosgrove LJ
    J Biol Chem; 2008 Feb; 283(9):5355-63. PubMed ID: 18056713
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of the affinities of insulin-like growth factor (IGF)-binding proteins 1-4 for IGF-I, IGF-II, IGF-I/insulin hybrid, and IGF-I analogs.
    Oh Y; Müller HL; Lee DY; Fielder PJ; Rosenfeld RG
    Endocrinology; 1993 Mar; 132(3):1337-44. PubMed ID: 7679979
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutations at positions 11 and 60 of insulin-like growth factor 1 reveal differences between its interactions with the type I insulin-like-growth-factor receptor and the insulin receptor.
    Hodgson DR; May FE; Westley BR
    Eur J Biochem; 1995 Oct; 233(1):299-309. PubMed ID: 7588759
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Signaling-competent receptor chimeras allow mapping of major insulin receptor binding domain determinants.
    Schumacher R; Soos MA; Schlessinger J; Brandenburg D; Siddle K; Ullrich A
    J Biol Chem; 1993 Jan; 268(2):1087-94. PubMed ID: 7678247
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of common ligand binding determinants of the insulin and insulin-like growth factor 1 receptors. Insights into mechanisms of ligand binding.
    Mynarcik DC; Williams PF; Schaffer L; Yu GQ; Whittaker J
    J Biol Chem; 1997 Jul; 272(30):18650-5. PubMed ID: 9228034
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Functional characterization of hybrid receptors composed of a truncated insulin receptor and wild type insulin-like growth factor 1 or insulin receptors.
    Langlois WJ; Sasaoka T; Yip CC; Olefsky JM
    Endocrinology; 1995 May; 136(5):1978-86. PubMed ID: 7720646
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [The structural organization of binding determinants in insulin-like growth factor-I (IGF-I) molecule].
    Kolychev AP
    Zh Evol Biokhim Fiziol; 2010; 46(1):74-94. PubMed ID: 20297673
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Binding affinities of insulin-like growth factor-I (IGF-I) fusion proteins to IGF binding protein 1 and IGF-I receptor are not correlated with mitogenic activity.
    Jansson M; Dixelius J; Uhlen M; Nilsson BO
    FEBS Lett; 1997 Oct; 416(3):259-64. PubMed ID: 9373165
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differential activation of insulin receptor substrates 1 and 2 by insulin-like growth factor-activated insulin receptors.
    Denley A; Carroll JM; Brierley GV; Cosgrove L; Wallace J; Forbes B; Roberts CT
    Mol Cell Biol; 2007 May; 27(10):3569-77. PubMed ID: 17325037
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterisation of receptors for IGF-I and insulin; evidence for hybrid insulin/IGF-I receptor in human coronary artery endothelial cells.
    Chisalita SI; Nitert MD; Arnqvist HJ
    Growth Horm IGF Res; 2006 Aug; 16(4):258-66. PubMed ID: 16914341
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Specificity of insulin and insulin-like growth factor I receptors investigated using chimeric mini-receptors. Role of C-terminal of receptor alpha subunit.
    Kristensen C; Wiberg FC; Andersen AS
    J Biol Chem; 1999 Dec; 274(52):37351-6. PubMed ID: 10601304
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of insulin/IGF hybrid receptors: contributions of the insulin receptor L2 and Fn1 domains and the alternatively spliced exon 11 sequence to ligand binding and receptor activation.
    Benyoucef S; Surinya KH; Hadaschik D; Siddle K
    Biochem J; 2007 May; 403(3):603-13. PubMed ID: 17291192
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Involvement of phenylalanine 23 in the binding of IGF-1 to the insulin and type I IGF receptor.
    Hodgson DR; May FE; Westley BR
    Regul Pept; 1996 Oct; 66(3):191-6. PubMed ID: 8916274
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural determinants of ligand recognition by type I insulin-like growth factor receptors: use of semisynthetic insulin analog probes.
    Cara JF; Nakagawa SH; Tager HS
    Endocrinology; 1988 Jun; 122(6):2881-7. PubMed ID: 2967179
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved.
    Pandini G; Frasca F; Mineo R; Sciacca L; Vigneri R; Belfiore A
    J Biol Chem; 2002 Oct; 277(42):39684-95. PubMed ID: 12138094
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.