BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

215 related articles for article (PubMed ID: 8445027)

  • 1. Familial glucocorticoid resistance caused by a splice site deletion in the human glucocorticoid receptor gene.
    Karl M; Lamberts SW; Detera-Wadleigh SD; Encio IJ; Stratakis CA; Hurley DM; Accili D; Chrousos GP
    J Clin Endocrinol Metab; 1993 Mar; 76(3):683-9. PubMed ID: 8445027
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Female pseudohermaphroditism caused by a novel homozygous missense mutation of the GR gene.
    Mendonca BB; Leite MV; de Castro M; Kino T; Elias LL; Bachega TA; Arnhold IJ; Chrousos GP; Latronico AC
    J Clin Endocrinol Metab; 2002 Apr; 87(4):1805-9. PubMed ID: 11932321
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel, C-terminal dominant negative mutation of the GR causes familial glucocorticoid resistance through abnormal interactions with p160 steroid receptor coactivators.
    Vottero A; Kino T; Combe H; Lecomte P; Chrousos GP
    J Clin Endocrinol Metab; 2002 Jun; 87(6):2658-67. PubMed ID: 12050230
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A novel point mutation in the ligand-binding domain (LBD) of the human glucocorticoid receptor (hGR) causing generalized glucocorticoid resistance: the importance of the C terminus of hGR LBD in conferring transactivational activity.
    Charmandari E; Raji A; Kino T; Ichijo T; Tiulpakov A; Zachman K; Chrousos GP
    J Clin Endocrinol Metab; 2005 Jun; 90(6):3696-705. PubMed ID: 15769988
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Point mutation causing a single amino acid substitution in the hormone binding domain of the glucocorticoid receptor in familial glucocorticoid resistance.
    Hurley DM; Accili D; Stratakis CA; Karl M; Vamvakopoulos N; Rorer E; Constantine K; Taylor SI; Chrousos GP
    J Clin Invest; 1991 Feb; 87(2):680-6. PubMed ID: 1704018
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Glucocorticoid receptor structure and function in glucocorticoid-resistant small cell lung carcinoma cells.
    Ray DW; Davis JR; White A; Clark AJ
    Cancer Res; 1996 Jul; 56(14):3276-80. PubMed ID: 8764121
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Splice site mutation in the glucocorticoid receptor gene causes resistance to glucocorticoid-induced apoptosis in a human acute leukemic cell line.
    Strasser-Wozak EM; Hattmannstorfer R; Hála M; Hartmann BL; Fiegl M; Geley S; Kofler R
    Cancer Res; 1995 Jan; 55(2):348-53. PubMed ID: 7812967
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Familial glucocorticoid resistance caused by a novel frameshift glucocorticoid receptor mutation.
    Trebble P; Matthews L; Blaikley J; Wayte AW; Black GC; Wilton A; Ray DW
    J Clin Endocrinol Metab; 2010 Dec; 95(12):E490-9. PubMed ID: 20861124
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutation creating a new splice site in the growth hormone receptor genes of 37 Ecuadorean patients with Laron syndrome.
    Berg MA; Guevara-Aguirre J; Rosenbloom AL; Rosenfeld RG; Francke U
    Hum Mutat; 1992; 1(1):24-32. PubMed ID: 1284474
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Glucocorticosteroid resistance in humans. Elucidation of the molecular mechanisms and implications for pathophysiology.
    Stratakis CA; Karl M; Schulte HM; Chrousos GP
    Ann N Y Acad Sci; 1994 Nov; 746():362-74; discussion 374-6. PubMed ID: 7825890
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cloning and expression of mutant glucocorticoid receptors from glucocorticoid-sensitive and -resistant human leukemic cells.
    Powers JH; Hillmann AG; Tang DC; Harmon JM
    Cancer Res; 1993 Sep; 53(17):4059-65. PubMed ID: 8358735
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Genotype-phenotype correlation in a family with primary cortisol resistance: possible modulating effect of the ER22/23EK polymorphism.
    Raef H; Baitei EY; Zou M; Shi Y
    Eur J Endocrinol; 2008 Apr; 158(4):577-82. PubMed ID: 18362306
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The N363S and I559N single nucleotide polymorphisms of the h-GR/NR3C1 gene in patients with bronchial asthma.
    Panek M; Pietras T; Antczak A; Fabijan A; Przemęcka M; Górski P; Kuna P; Szemraj J
    Int J Mol Med; 2012 Jul; 30(1):142-50. PubMed ID: 22469783
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Multiple promoters exist in the human GR gene, one of which is activated by glucocorticoids.
    Breslin MB; Geng CD; Vedeckis WV
    Mol Endocrinol; 2001 Aug; 15(8):1381-95. PubMed ID: 11463861
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Five patients with biochemical and/or clinical generalized glucocorticoid resistance without alterations in the glucocorticoid receptor gene.
    Huizenga NA; de Lange P; Koper JW; de Herder WW; Abs R; Kasteren JH; de Jong FH; Lamberts SW
    J Clin Endocrinol Metab; 2000 May; 85(5):2076-81. PubMed ID: 10843199
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Repression of the human glycoprotein hormone alpha-subunit gene by glucocorticoids: evidence for receptor interactions with limiting transcriptional activators.
    Chatterjee VK; Madison LD; Mayo S; Jameson JL
    Mol Endocrinol; 1991 Jan; 5(1):100-10. PubMed ID: 1708098
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human hypertension caused by mutations in the 11 beta-hydroxysteroid dehydrogenase gene: a molecular analysis of apparent mineralocorticoid excess.
    Whorwood CB; Stewart PM
    J Hypertens Suppl; 1996 Dec; 14(5):S19-24. PubMed ID: 9120678
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel point mutation in helix 11 of the ligand-binding domain of the human glucocorticoid receptor gene causing generalized glucocorticoid resistance.
    Charmandari E; Kino T; Ichijo T; Jubiz W; Mejia L; Zachman K; Chrousos GP
    J Clin Endocrinol Metab; 2007 Oct; 92(10):3986-90. PubMed ID: 17635946
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Generalized glucocorticoid resistance caused by a novel two-nucleotide deletion in the hormone-binding domain of the glucocorticoid receptor gene NR3C1.
    Donner KM; Hiltunen TP; Jänne OA; Sane T; Kontula K
    Eur J Endocrinol; 2013 Jan; 168(1):K9-K18. PubMed ID: 23076843
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Resistance to glucocorticoid-induced apoptosis in human T-cell acute lymphoblastic leukemia CEM-C1 cells is due to insufficient glucocorticoid receptor expression.
    Geley S; Hartmann BL; Hala M; Strasser-Wozak EM; Kapelari K; Kofler R
    Cancer Res; 1996 Nov; 56(21):5033-8. PubMed ID: 8895760
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.