These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

189 related articles for article (PubMed ID: 8447563)

  • 21. The association between fasting hypoglycemia and methylated mercaptopurine metabolites in children with acute lymphoblastic leukemia.
    Melachuri S; Gandrud L; Bostrom B
    Pediatr Blood Cancer; 2014 Jun; 61(6):1003-6. PubMed ID: 24415675
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Analysis of thiopurine S-methyltransferase polymorphism in the population of Serbia and Montenegro and mercaptopurine therapy tolerance in childhood acute lymphoblastic leukemia.
    Dokmanovic L; Urosevic J; Janic D; Jovanovic N; Petrucev B; Tosic N; Pavlovic S
    Ther Drug Monit; 2006 Dec; 28(6):800-6. PubMed ID: 17164697
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Thiopurine methyltransferase deficiency in childhood lymphoblastic leukaemia: 6-mercaptopurine dosage strategies.
    Lennard L; Lewis IJ; Michelagnoli M; Lilleyman JS
    Med Pediatr Oncol; 1997 Oct; 29(4):252-5. PubMed ID: 9251729
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Chronopharmacokinetics of oral methotrexate and 6-mercaptopurine: is there diurnal variation in the disposition of antileukemic therapy?
    Balis FM; Jeffries SL; Lange B; Murphy RF; Doherty KM; Arndt CA; Luery N; Poplack DG
    Am J Pediatr Hematol Oncol; 1989; 11(3):324-6. PubMed ID: 2782561
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Effects on transmethylation by high-dose 6-mercaptopurine and methotrexate infusions during consolidation treatment of acute lymphoblastic leukemia.
    Keuzenkamp-Jansen CW; De Abreu RA; Blom HJ; Bökkerink JP; Trijbels JM
    Biochem Pharmacol; 1996 May; 51(9):1165-71. PubMed ID: 8645339
    [TBL] [Abstract][Full Text] [Related]  

  • 26. [New techniques for optimization of thiopurine therapy in leukemia and transplantation].
    Loennechen T; Lysaa RA; Giverhaug T; Sylte I; Mathiesen LE; Aarbakke J
    Tidsskr Nor Laegeforen; 2002 Apr; 122(11):1107-10. PubMed ID: 12043054
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Thiopurine drugs in the treatment of childhood leukaemia: the influence of inherited thiopurine methyltransferase activity on drug metabolism and cytotoxicity.
    Lennard L; Welch JC; Lilleyman JS
    Br J Clin Pharmacol; 1997 Nov; 44(5):455-61. PubMed ID: 9384462
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Cell-kinetics and biochemical pharmacology of methotrexate and 6-mercaptopurine in human malignant T-lymphoblasts.
    Bökkerink JP; De Abreu RA; Stet EH; Damen FJ
    Klin Padiatr; 1992; 204(4):293-8. PubMed ID: 1518268
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The thiopurine methyltransferase genetic polymorphism is associated with thioguanine-related veno-occlusive disease of the liver in children with acute lymphoblastic leukemia.
    Lennard L; Richards S; Cartwright CS; Mitchell C; Lilleyman JS; Vora A;
    Clin Pharmacol Ther; 2006 Oct; 80(4):375-83. PubMed ID: 17015055
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Measures of 6-mercaptopurine and methotrexate maintenance therapy intensity in childhood acute lymphoblastic leukemia.
    Nielsen SN; Grell K; Nersting J; Frandsen TL; Hjalgrim LL; Schmiegelow K
    Cancer Chemother Pharmacol; 2016 Nov; 78(5):983-994. PubMed ID: 27600880
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Continuing therapy for childhood acute lymphoblastic leukaemia: clinical and cellular pharmacology of methotrexate, 6-mercaptopurine and 6-thioguanine.
    Estlin EJ
    Cancer Treat Rev; 2001 Dec; 27(6):351-63. PubMed ID: 11908928
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Pharmacokinetics of tablet and liquid formulations of oral 6-mercaptopurine in children with acute lymphoblastic leukemia.
    Larsen RH; Hjalgrim LL; Grell K; Kristensen K; Pedersen LG; Brünner ED; Als-Nielsen B; Schmiegelow K; Nersting J
    Cancer Chemother Pharmacol; 2020 Jul; 86(1):25-32. PubMed ID: 32519032
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Quantification of Thiopurine Nucleotides in Erythrocytes and Clinical Application to Pediatric Acute Lymphoblastic Leukemia.
    Moon SY; Lim JH; Kim EH; Nam Y; Yu KS; Hong KT; Choi JY; Hong CR; Kim H; Kang HJ; Shin HY; Lee K; Song J; Lee SY; Song SH
    Ther Drug Monit; 2019 Feb; 41(1):75-85. PubMed ID: 30507626
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Application of HPLC to study the kinetics of a branched bi-enzyme system consisting of hypoxanthine-guanine phosphoribosyltransferase and xanthine oxidase--an important biochemical system to evaluate the efficiency of the anticancer drug 6-mercaptopurine in ALL cell line.
    Kalra S; Paul MK; Balaram H; Mukhopadhyay AK
    J Chromatogr B Analyt Technol Biomed Life Sci; 2007 May; 850(1-2):7-14. PubMed ID: 17081813
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Maintenance Treatment With Low-Dose Mercaptopurine in Combination With Allopurinol in Children With Acute Lymphoblastic Leukemia and Mercaptopurine-Induced Pancreatitis.
    Zerra P; Bergsagel J; Keller FG; Lew G; Pauly M
    Pediatr Blood Cancer; 2016 Apr; 63(4):712-5. PubMed ID: 26878433
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Thiopurine Enhanced ALL Maintenance (TEAM): study protocol for a randomized study to evaluate the improvement in disease-free survival by adding very low dose 6-thioguanine to 6-mercaptopurine/methotrexate-based maintenance therapy in pediatric and adult patients (0-45 years) with newly diagnosed B-cell precursor or T-cell acute lymphoblastic leukemia treated according to the intermediate risk-high group of the ALLTogether1 protocol.
    Toksvang LN; Als-Nielsen B; Bacon C; Bertasiute R; Duarte X; Escherich G; Helgadottir EA; Johannsdottir IR; Jónsson ÓG; Kozlowski P; Langenskjöld C; Lepik K; Niinimäki R; Overgaard UM; Punab M; Räty R; Segers H; van der Sluis I; Smith OP; Strullu M; Vaitkevičienė G; Wik HS; Heyman M; Schmiegelow K
    BMC Cancer; 2022 May; 22(1):483. PubMed ID: 35501736
    [TBL] [Abstract][Full Text] [Related]  

  • 37. 6-Thioguanine nucleotide accumulation in red blood cells during maintenance chemotherapy for childhood acute lymphoblastic leukemia, and its relation to leukopenia.
    Schmiegelow K; Bruunshuus I
    Cancer Chemother Pharmacol; 1990; 26(4):288-92. PubMed ID: 2369793
    [TBL] [Abstract][Full Text] [Related]  

  • 38. DNA-thioguanine nucleotide as a treatment marker in acute lymphoblastic leukemia patients with NUDT15 variant genotypes.
    Ju HY; Lee JW; Cho HW; Hyun JK; Ma Y; Yi ES; Yoo KH; Sung KW; Choi R; Koo HH; Lee SY
    PLoS One; 2021; 16(1):e0245667. PubMed ID: 33481917
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Thiopurine methyltransferase: a review and a clinical pilot study.
    Keuzenkamp-Jansen CW; Leegwater PA; De Abreu RA; Lambooy MA; Bokkerink JP; Trijbels JM
    J Chromatogr B Biomed Appl; 1996 Mar; 678(1):15-22. PubMed ID: 8861653
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Erythrocyte concentrations of metabolites or cumulative doses of 6-mercaptopurine and methotrexate do not predict liver changes in children treated for acute lymphoblastic leukemia.
    Halonen P; Mattila J; Mäkipernaa A; Ruuska T; Schmiegelow K
    Pediatr Blood Cancer; 2006 Jun; 46(7):762-6. PubMed ID: 16395677
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.