235 related articles for article (PubMed ID: 8452558)
1. Primary and secondary oxidative metabolism of dextromethorphan. In vitro studies with female Sprague-Dawley and Dark Agouti rat liver microsomes.
Kerry NL; Somogyi AA; Mikus G; Bochner F
Biochem Pharmacol; 1993 Feb; 45(4):833-9. PubMed ID: 8452558
[TBL] [Abstract][Full Text] [Related]
2. The role of CYP2D6 in primary and secondary oxidative metabolism of dextromethorphan: in vitro studies using human liver microsomes.
Kerry NL; Somogyi AA; Bochner F; Mikus G
Br J Clin Pharmacol; 1994 Sep; 38(3):243-8. PubMed ID: 7826826
[TBL] [Abstract][Full Text] [Related]
3. Codeine O-demethylation: rat strain differences and the effects of inhibitors.
Mikus G; Somogyi AA; Bochner F; Eichelbaum M
Biochem Pharmacol; 1991 Mar; 41(5):757-62. PubMed ID: 1998530
[TBL] [Abstract][Full Text] [Related]
4. Metabolism of dextromethorphan in vitro: involvement of cytochromes P450 2D6 and 3A3/4, with a possible role of 2E1.
Schmider J; Greenblatt DJ; Fogelman SM; von Moltke LL; Shader RI
Biopharm Drug Dispos; 1997 Apr; 18(3):227-40. PubMed ID: 9113345
[TBL] [Abstract][Full Text] [Related]
5. CYP2D6- and CYP3A-dependent metabolism of dextromethorphan in humans.
Jacqz-Aigrain E; Funck-Brentano C; Cresteil T
Pharmacogenetics; 1993 Aug; 3(4):197-204. PubMed ID: 8220439
[TBL] [Abstract][Full Text] [Related]
6. An evaluation of cytochrome P450 isoform activities in the female dark agouti (DA) rat: relevance to its use as a model of the CYP2D6 poor metaboliser phenotype.
Barham HM; Lennard MS; Tucker GT
Biochem Pharmacol; 1994 Apr; 47(8):1295-307. PubMed ID: 8185638
[TBL] [Abstract][Full Text] [Related]
7. Dextromethorphan metabolism in rat: interstrain differences and the fate of individually administered oxidative metabolites.
Bochner F; Somogyi AA; Chen ZR
Xenobiotica; 1994 Jun; 24(6):543-52. PubMed ID: 7975720
[TBL] [Abstract][Full Text] [Related]
8. In-vivo and in-vitro dextromethorphan metabolism in SD and DA rat. An animal model of the debrisoquine-type polymorphic oxidation in man.
Zysset T; Zeugin T; Küpfer A
Biochem Pharmacol; 1988 Aug; 37(16):3155-60. PubMed ID: 3401246
[TBL] [Abstract][Full Text] [Related]
9. Demethylation of radiolabelled dextromethorphan in rat microsomes and intact hepatocytes.
Di Marco A; Yao D; Laufer R
Eur J Biochem; 2003 Sep; 270(18):3768-77. PubMed ID: 12950260
[TBL] [Abstract][Full Text] [Related]
10. Characterization of dextromethorphan N-demethylation by human liver microsomes. Contribution of the cytochrome P450 3A (CYP3A) subfamily.
Gorski JC; Jones DR; Wrighton SA; Hall SD
Biochem Pharmacol; 1994 Jul; 48(1):173-82. PubMed ID: 8043020
[TBL] [Abstract][Full Text] [Related]
11. Comparative contribution to dextromethorphan metabolism by cytochrome P450 isoforms in vitro: can dextromethorphan be used as a dual probe for both CTP2D6 and CYP3A activities?
Yu A; Haining RL
Drug Metab Dispos; 2001 Nov; 29(11):1514-20. PubMed ID: 11602530
[TBL] [Abstract][Full Text] [Related]
12. Dextromethorphan O-demethylation in liver microsomes as a prototype reaction to monitor cytochrome P-450 db1 activity.
Dayer P; Leemann T; Striberni R
Clin Pharmacol Ther; 1989 Jan; 45(1):34-40. PubMed ID: 2910636
[TBL] [Abstract][Full Text] [Related]
13. Thebaine O-demethylation to oripavine: genetic differences between two rat strains.
Mikus G; Somogyi AA; Bochner F; Eichelbaum M
Xenobiotica; 1991 Nov; 21(11):1501-9. PubMed ID: 1763524
[TBL] [Abstract][Full Text] [Related]
14. Characterization of the human cytochrome P450 enzymes involved in the metabolism of dihydrocodeine.
Kirkwood LC; Nation RL; Somogyi AA
Br J Clin Pharmacol; 1997 Dec; 44(6):549-55. PubMed ID: 9431830
[TBL] [Abstract][Full Text] [Related]
15. Pharmacogenetics of dextromethorphan O-demethylation in man.
Küpfer A; Schmid B; Pfaff G
Xenobiotica; 1986 May; 16(5):421-33. PubMed ID: 3739367
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of debrisoquin clearance in perfused rat livers and inhibition of dextromethorphan metabolism in human liver microsomes by 4-hydroxydebrisoquin or other metabolites of debrisoquin.
Jaruratanasirikul S; Cooper AD; Blaschke TF
Drug Metab Dispos; 1992; 20(3):379-82. PubMed ID: 1355711
[TBL] [Abstract][Full Text] [Related]
17. Dextromethorphan metabolism in Jordanians: dissociation of dextromethorphan O-demethylation from debrisoquine 4-hydroxylation.
Irshaid YM; al-Hadidi HF; Latif A; Awwadi F; al-Zoubi M; Rawashdeh NM
Eur J Drug Metab Pharmacokinet; 1996; 21(4):301-7. PubMed ID: 9074894
[TBL] [Abstract][Full Text] [Related]
18. Metabolism of dexfenfluramine in human liver microsomes and by recombinant enzymes: role of CYP2D6 and 1A2.
Haritos VS; Ching MS; Ghabrial H; Gross AS; Taavitsainen P; Pelkonen O; Battaglia SE; Smallwood RA; Ahokas JT
Pharmacogenetics; 1998 Oct; 8(5):423-32. PubMed ID: 9825834
[TBL] [Abstract][Full Text] [Related]
19. The effect of cimetidine on dextromethorphan O-demethylase activity of human liver microsomes and recombinant CYP2D6.
Madeira M; Levine M; Chang TK; Mirfazaelian A; Bellward GD
Drug Metab Dispos; 2004 Apr; 32(4):460-7. PubMed ID: 16680870
[TBL] [Abstract][Full Text] [Related]
20. UPLC-MS/MS analysis of dextromethorphan-O-demethylation kinetics in rat brain microsomes.
DuBois BN; Mehvar R
J Chromatogr B Analyt Technol Biomed Life Sci; 2018 Oct; 1096():66-72. PubMed ID: 30149296
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
