These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

232 related articles for article (PubMed ID: 8452558)

  • 21. Oxidation of R(+)- and S(-)-carvedilol by rat liver microsomes. Evidence for stereoselective oxidation and characterization of the cytochrome P450 isozymes involved.
    Fujimaki M
    Drug Metab Dispos; 1994; 22(5):700-8. PubMed ID: 7835220
    [TBL] [Abstract][Full Text] [Related]  

  • 22. High-performance liquid chromatographic assays for bufuralol 1'-hydroxylase, debrisoquine 4-hydroxylase, and dextromethorphan O-demethylase in microsomes and purified cytochrome P-450 isozymes of human liver.
    Kronbach T; Mathys D; Gut J; Catin T; Meyer UA
    Anal Biochem; 1987 Apr; 162(1):24-32. PubMed ID: 3605590
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes.
    Lalovic B; Phillips B; Risler LL; Howald W; Shen DD
    Drug Metab Dispos; 2004 Apr; 32(4):447-54. PubMed ID: 15039299
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Limitations of dextromethorphan N-demethylation as a measure of CYP3A activity.
    Kashuba AD; Nafziger AN; Kearns GL; Leeder JS; Gotschall R; Gaedigk A; Bertino JS
    Pharmacogenetics; 1999 Aug; 9(4):453-62. PubMed ID: 10780265
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Cytochrome P450-dependent metabolism of dextromethorphan: fetal and adult studies.
    Jacqz-Aigrain E; Cresteil T
    Dev Pharmacol Ther; 1992; 18(3-4):161-8. PubMed ID: 1306804
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Polymorphic formation of morphine from codeine in poor and extensive metabolizers of dextromethorphan: relationship to the presence of immunoidentified cytochrome P-450IID1.
    Mortimer O; Persson K; Ladona MG; Spalding D; Zanger UM; Meyer UA; Rane A
    Clin Pharmacol Ther; 1990 Jan; 47(1):27-35. PubMed ID: 2295216
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Inhibitory studies of mexiletine and dextromethorphan oxidation in human liver microsomes.
    Broly F; Libersa C; Lhermitte M; Dupuis B
    Biochem Pharmacol; 1990 Mar; 39(6):1045-53. PubMed ID: 2322292
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Sigmoidal kinetics of CYP3A substrates: an approach for scaling dextromethorphan metabolism in hepatic microsomes and isolated hepatocytes to predict in vivo clearance in rat.
    Witherow LE; Houston JB
    J Pharmacol Exp Ther; 1999 Jul; 290(1):58-65. PubMed ID: 10381760
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The inhibitory effect of amiodarone and desethylamiodarone on dextromethorphan O-demethylation in human and rat liver microsomes.
    Jaruratanasirikul S; Hortiwakul R
    J Pharm Pharmacol; 1994 Nov; 46(11):933-5. PubMed ID: 7897605
    [TBL] [Abstract][Full Text] [Related]  

  • 30. A radiometric TLC assay of liver microsomal dextromethorphan O-demethylation.
    Singh SP; Moody DE
    J Pharm Biomed Anal; 1995 Jul; 13(8):1027-32. PubMed ID: 8580147
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Enzyme kinetic modelling as a tool to analyse the behaviour of cytochrome P450 catalysed reactions: application to amitriptyline N-demethylation.
    Schmider J; Greenblatt DJ; Harmatz JS; Shader RI
    Br J Clin Pharmacol; 1996 Jun; 41(6):593-604. PubMed ID: 8799527
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Phenotypic differences in dextromethorphan metabolism.
    Vetticaden SJ; Cabana BE; Prasad VK; Purich ED; Jonkman JH; de Zeeuw R; Ball L; Leeson LJ; Braun RL
    Pharm Res; 1989 Jan; 6(1):13-9. PubMed ID: 2717511
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Determination of cytochrome P450 3A4/5 activity in vivo with dextromethorphan N-demethylation.
    Jones DR; Gorski JC; Haehner BD; O'Mara EM; Hall SD
    Clin Pharmacol Ther; 1996 Oct; 60(4):374-84. PubMed ID: 8873685
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Ethylmorphine O-deethylation in isolated rat hepatocytes. Involvement of codeine O-demethylation enzyme systems.
    Xu BQ; Aasmundstad TA; Bjørneboe A; Christophersen AS; Mørland J
    Biochem Pharmacol; 1995 Feb; 49(4):453-60. PubMed ID: 7872951
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Microsomal oxidation of N,N-diethylformamide and its effect on P450-dependent monooxygenases in rat liver.
    Amato G; Longo V; Mazzaccaro A; Gervasi PG
    Chem Res Toxicol; 1996; 9(5):882-90. PubMed ID: 8828925
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Expression, purification, and characterization of mouse CYP2d22.
    Yu AM; Haining RL
    Drug Metab Dispos; 2006 Jul; 34(7):1167-74. PubMed ID: 16595712
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The molecular mechanisms of two common polymorphisms of drug oxidation--evidence for functional changes in cytochrome P-450 isozymes catalysing bufuralol and mephenytoin oxidation.
    Meyer UA; Gut J; Kronbach T; Skoda C; Meier UT; Catin T; Dayer P
    Xenobiotica; 1986 May; 16(5):449-64. PubMed ID: 2874666
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Dextromethorphan as an in vivo probe for the simultaneous determination of CYP2D6 and CYP3A activity.
    Ducharme J; Abdullah S; Wainer IW
    J Chromatogr B Biomed Appl; 1996 Mar; 678(1):113-28. PubMed ID: 8861661
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Characterization of dextromethorphan O- and N-demethylation catalyzed by highly purified recombinant human CYP2D6.
    Yu A; Dong H; Lang D; Haining RL
    Drug Metab Dispos; 2001 Nov; 29(11):1362-5. PubMed ID: 11602510
    [TBL] [Abstract][Full Text] [Related]  

  • 40. CYP2D6 and CYP3A4 involvement in the primary oxidative metabolism of hydrocodone by human liver microsomes.
    Hutchinson MR; Menelaou A; Foster DJ; Coller JK; Somogyi AA
    Br J Clin Pharmacol; 2004 Mar; 57(3):287-97. PubMed ID: 14998425
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.