172 related articles for article (PubMed ID: 8459830)
1. Peptide-fluoromethyl ketones arrest intracellular replication and intercellular transmission of Trypanosoma cruzi.
Harth G; Andrews N; Mills AA; Engel JC; Smith R; McKerrow JH
Mol Biochem Parasitol; 1993 Mar; 58(1):17-24. PubMed ID: 8459830
[TBL] [Abstract][Full Text] [Related]
2. Biotin-labelled peptidyl diazomethane inhibitors derived from the substrate-like sequence of cystatin: targeting of the active site of cruzipain, the major cysteine proteinase of Trypanosoma cruzi.
Lalmanach G; Mayer R; Serveau C; Scharfstein J; Gauthier F
Biochem J; 1996 Sep; 318 ( Pt 2)(Pt 2):395-9. PubMed ID: 8809025
[TBL] [Abstract][Full Text] [Related]
3. A role for protease activity and host-cell permeability during the process of Trypanosoma cruzi egress from infected cells.
Costales J; Rowland EC
J Parasitol; 2007 Dec; 93(6):1350-9. PubMed ID: 18314679
[TBL] [Abstract][Full Text] [Related]
4. The sequence, organization, and expression of the major cysteine protease (cruzain) from Trypanosoma cruzi.
Eakin AE; Mills AA; Harth G; McKerrow JH; Craik CS
J Biol Chem; 1992 Apr; 267(11):7411-20. PubMed ID: 1559982
[TBL] [Abstract][Full Text] [Related]
5. The crystal structure of cruzain: a therapeutic target for Chagas' disease.
McGrath ME; Eakin AE; Engel JC; McKerrow JH; Craik CS; Fletterick RJ
J Mol Biol; 1995 Mar; 247(2):251-9. PubMed ID: 7707373
[TBL] [Abstract][Full Text] [Related]
6. The properties of peptidyl diazoethanes and chloroethanes as protease inactivators.
Wikstrom P; Kirschke H; Stone S; Shaw E
Arch Biochem Biophys; 1989 Apr; 270(1):286-93. PubMed ID: 2930191
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and biological activity of a series of potent fluoromethyl ketone inhibitors of recombinant human calpain I.
Chatterjee S; Ator MA; Bozyczko-Coyne D; Josef K; Wells G; Tripathy R; Iqbal M; Bihovsky R; Senadhi SE; Mallya S; O'Kane TM; McKenna BA; Siman R; Mallamo JP
J Med Chem; 1997 Nov; 40(23):3820-8. PubMed ID: 9371247
[TBL] [Abstract][Full Text] [Related]
8. Effects of proteinase inhibitors on the growth and differentiation of Trypanosoma cruzi.
Franke de Cazzulo BM; MartÃnez J; North MJ; Coombs GH; Cazzulo JJ
FEMS Microbiol Lett; 1994 Nov; 124(1):81-6. PubMed ID: 8001773
[TBL] [Abstract][Full Text] [Related]
9. Identification of potent and selective mechanism-based inhibitors of the cysteine protease cruzain using solid-phase parallel synthesis.
Huang L; Lee A; Ellman JA
J Med Chem; 2002 Jan; 45(3):676-84. PubMed ID: 11806719
[TBL] [Abstract][Full Text] [Related]
10. Crystal structure of the parasite protease inhibitor chagasin in complex with a host target cysteine protease.
Ljunggren A; Redzynia I; Alvarez-Fernandez M; Abrahamson M; Mort JS; Krupa JC; Jaskolski M; Bujacz G
J Mol Biol; 2007 Aug; 371(1):137-53. PubMed ID: 17561110
[TBL] [Abstract][Full Text] [Related]
11. Identification of a new class of nonpeptidic inhibitors of cruzain.
Brak K; Doyle PS; McKerrow JH; Ellman JA
J Am Chem Soc; 2008 May; 130(20):6404-10. PubMed ID: 18435536
[TBL] [Abstract][Full Text] [Related]
12. Cysteine protease inhibitors cure an experimental Trypanosoma cruzi infection.
Engel JC; Doyle PS; Hsieh I; McKerrow JH
J Exp Med; 1998 Aug; 188(4):725-34. PubMed ID: 9705954
[TBL] [Abstract][Full Text] [Related]
13. Plasmodium falciparum: inhibitors of lysosomal cysteine proteinases inhibit a trophozoite proteinase and block parasite development.
Rosenthal PJ; McKerrow JH; Rasnick D; Leech JH
Mol Biochem Parasitol; 1989 Jun; 35(2):177-83. PubMed ID: 2671722
[TBL] [Abstract][Full Text] [Related]
14. Discrimination of cruzipain, the major cysteine proteinase of Trypanosoma cruzi, and mammalian cathepsins B and L, by a pH-inducible fluorogenic substrate of trypanosomal cysteine proteinases.
Serveau C; Lalmanach G; Hirata I; Scharfstein J; Juliano MA; Gauthier F
Eur J Biochem; 1999 Jan; 259(1-2):275-80. PubMed ID: 9914503
[TBL] [Abstract][Full Text] [Related]
15. Leishmania major: comparison of the cathepsin L- and B-like cysteine protease genes with those of other trypanosomatids.
Sakanari JA; Nadler SA; Chan VJ; Engel JC; Leptak C; Bouvier J
Exp Parasitol; 1997 Jan; 85(1):63-76. PubMed ID: 9024203
[TBL] [Abstract][Full Text] [Related]
16. Gold compounds as cysteine protease inhibitors: perspectives for pharmaceutical application as antiparasitic agents.
Massai L; Messori L; Micale N; Schirmeister T; Maes L; Fregona D; Cinellu MA; Gabbiani C
Biometals; 2017 Apr; 30(2):313-320. PubMed ID: 28283781
[TBL] [Abstract][Full Text] [Related]
17. General solid-phase method to prepare novel cyclic ketone inhibitors of the cysteine protease cruzain.
Huang L; Ellman JA
Bioorg Med Chem Lett; 2002 Oct; 12(20):2993-6. PubMed ID: 12270191
[TBL] [Abstract][Full Text] [Related]
18. The Trypanosoma cruzi protease cruzain mediates immune evasion.
Doyle PS; Zhou YM; Hsieh I; Greenbaum DC; McKerrow JH; Engel JC
PLoS Pathog; 2011 Sep; 7(9):e1002139. PubMed ID: 21909255
[TBL] [Abstract][Full Text] [Related]
19. Inhibitors of the major cysteinyl proteinase (GP57/51) impair host cell invasion and arrest the intracellular development of Trypanosoma cruzi in vitro.
Meirelles MN; Juliano L; Carmona E; Silva SG; Costa EM; Murta AC; Scharfstein J
Mol Biochem Parasitol; 1992 Jun; 52(2):175-84. PubMed ID: 1620157
[TBL] [Abstract][Full Text] [Related]
20. Design of Gallinamide A Analogs as Potent Inhibitors of the Cysteine Proteases Human Cathepsin L and
Boudreau PD; Miller BW; McCall LI; Almaliti J; Reher R; Hirata K; Le T; Siqueira-Neto JL; Hook V; Gerwick WH
J Med Chem; 2019 Oct; 62(20):9026-9044. PubMed ID: 31539239
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]