These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 8464039)

  • 1. Synthesis and biodistribution of iodine-125-labeled 1-azabicyclo[2.2.2]oct-3-yl alpha-hydroxy-alpha-(1-iodo-1-propen-3-yl)-alpha-phenylacetate. A new ligand for the potential imaging of muscarinic receptors by single photon emission computed tomography.
    McPherson DW; DeHaven-Hudkins DL; Callahan AP; Knapp FF
    J Med Chem; 1993 Apr; 36(7):848-54. PubMed ID: 8464039
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Resolution and in vitro and initial in vivo evaluation of isomers of iodine-125-labeled 1-azabicyclo[2.2.2]oct-3-yl alpha-hydroxy-alpha-(1-iodo-1-propen-3-yl)-alpha-phenylacetate: a high-affinity ligand for the muscarinic receptor.
    McPherson DW; Lambert CR; Jahn K; Sood V; McRee RC; Zeeberg B; Reba RC; Knapp FF
    J Med Chem; 1995 Sep; 38(20):3908-17. PubMed ID: 7562924
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vivo autoradiographic competition studies of isomers of [125I]IQNP against QNB demonstrating in vivo m2 muscarinic subtype selectivity for QNB.
    Zeeberg BR; Boulay SF; Sood VK; Rayeq MR; Danesh RA; McPherson DW; Knapp FF
    Recept Signal Transduct; 1997; 7(1):45-54. PubMed ID: 9285530
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In vivo autoradiographic and dissection evaluation of isomers of 125I-labeled 1-azabicyclo[2.2.2] oct-3-yl-alpha-(1-iodo-1-propen-3-yl)-alpha-phenylacetate (IQNP).
    Rayeq MR; Boulay SF; Sood VK; McPherson DW; Knapp FF; Zeeberg BR
    Recept Signal Transduct; 1996; 6(1):13-34. PubMed ID: 8933619
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of in vivo brain muscarinic acetylcholine receptor subtype selectivity by competition studies against (R,S)-[125I]IQNB.
    Gitler MS; Boulay SF; Sood VK; McPherson DW; Knap FF; Zeeberg BR; Reba RC
    Brain Res; 1995 Jul; 687(1-2):71-8. PubMed ID: 7583315
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evaluation of Z-(R,R)-IQNP for the potential imaging of m2 mAChR rich regions of the brain and heart.
    McPherson DW; Greenbaum M; Luo H; Beets AL; Knapp FF
    Life Sci; 2000; 66(10):885-96. PubMed ID: 10714889
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Evaluation of 1-azabicyclo[2.2.2]oct-3-yl alpha-fluoroalkyl-alpha-hydroxy-alpha-phenylacetates as potential ligands for the study of muscarinic receptor density by positron emission tomography.
    Luo H; Hasan A; Sood V; McRee RC; Zeeberg B; Reba RC; McPherson DW; Knapp FF
    Nucl Med Biol; 1996 Apr; 23(3):267-76. PubMed ID: 8782236
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In vivo competition studies of Z-(-,-)-[125I]IQNP against 3-quinuclidinyl 2-(5-bromothienyl)-2-thienylglycolate (BrQNT) demonstrating in vivo m2 muscarinic subtype selectivity for BrQNT.
    Cohen VI; Zeeberg BR; Boulay SF; Sood VK; Rayeq MR; Danesh RA; McPherson DW; Reba RC
    J Mol Neurosci; 1998 Aug; 11(1):1-9. PubMed ID: 9826782
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Z-IQNP: a potential radioligand for SPECT imaging of muscarinic acetylcholine receptors in Alzheimer's disease.
    Nobuhara K; Halldin C; Hall H; Karlsson P; Farde L; Hiltunen J; McPherson DW; Savonen A; Bergström KA; Pauli S; Swahn CG; Larsson SA; Schnell PO; Sedvall G
    Psychopharmacology (Berl); 2000 Mar; 149(1):45-55. PubMed ID: 10789882
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Iodine-123 labelled Z-(R,R)-IQNP: a potential radioligand for visualization of M(1 )and M(2) muscarinic acetylcholine receptors in Alzheimer's disease.
    Bergström KA; Halldin C; Savonen A; Okubo Y; Hiltunen J; Nobuhara K; Swahn CG; Karlsson P; McPherson D; Knapp FF; Larsson S; Schnell PO; Farde L
    Eur J Nucl Med; 1999 Nov; 26(11):1482-5. PubMed ID: 10552091
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A rapid and simple Sep Pak method for purification of radioiodinated IQNP, a high affinity ligand for the muscarinic receptor.
    McPherson DW; Knapp FF
    Nucl Med Biol; 1999 Oct; 26(7):859-63. PubMed ID: 10628569
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evaluation and metabolite studies of 125I- and 123I-labelled E-(R,R)-IQNP: potential radioligands for visualization of M1 muscarinic acetylcholine receptors in brain.
    Bergström KA; Halldin C; Hiltunen J; Swahn CG; Ito H; Ginovart N; Hall H; McPherson DW; Knapp FF; Larsson S; Schnell PO; Farde L
    Nucl Med Biol; 1998 Apr; 25(3):209-14. PubMed ID: 9620625
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SPET imaging of central muscarinic acetylcholine receptors with iodine-123 labelled E-IQNP and Z-IQNP.
    Nobuhara K; Farde L; Halldin C; Karlsson P; Swahn CG; Olsson H; Bergström KA; Larsson SA; Schnell PO; McPherson DW; Savonen A; Hiltunen J; Sedvall G
    Eur J Nucl Med; 2001 Jan; 28(1):13-24. PubMed ID: 11202446
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [125I] 3-quinuclidinyl 4-iodobenzilate: a high affinity, high specific activity radioligand for the M1 and M2-acetylcholine receptors.
    Gibson RE; Rzeszotarski WJ; Jagoda EM; Francis BE; Reba RC; Eckelman WC
    Life Sci; 1984 Jun; 34(23):2287-96. PubMed ID: 6727565
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Stereoselective synthesis, in vitro, and initial in vivo evaluation of 1-methylpiperidin-4-yl alpha-hydroxy-alpha-(1-iodo-1-propen-3-yl)-alpha-phenylacetate (IPIP): a novel radioiodinated molecular probe with high affinity for the muscarinic receptor.
    McPherson DW; Breeden WK; Beets AL; Luo H; Sood V; Knapp FF
    Nucl Med Biol; 2001 Nov; 28(8):959-73. PubMed ID: 11711316
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and evaluation of radioiodinated derivatives of 1-azabicyclo[2.2.2]oct-3-yl alpha-hydroxy-alpha-(4-iodophenyl)-alpha- phenylacetate as potential radiopharmaceuticals.
    Rzeszotarski WJ; Eckelman WC; Francis BE; Simms DA; Gibson RE; Jagoda EM; Grissom MP; Eng RR; Conklin JJ; Reba RC
    J Med Chem; 1984 Feb; 27(2):156-60. PubMed ID: 6694164
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Preparation and properties of (R)-(-)-1-azabicyclo[2.2.2]oct-3-yl- (R)-(+)-alpha-hydroxy-alpha-(4-[125I]iodophenyl)-alpha-phenyl acetate and (R)-(-)-1-azabicyclo[2.2.2]oct-3-yl-(S)-(-)-alpha-hydroxy-alpha- (4-[125I]iodophenyl)-alpha-phenyl acetate as potential radiopharmaceuticals.
    Cohen VI; Rzeszotarski WJ; Gibson RE; Fan LH; Reba RC
    J Pharm Sci; 1989 Oct; 78(10):833-6. PubMed ID: 2600789
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Affinity and selectivity of the optical isomers of 3-quinuclidinyl benzilate and related muscarinic antagonists.
    Rzeszotarski WJ; McPherson DW; Ferkany JW; Kinnier WJ; Noronha-Blob L; Kirkien-Rzeszotarski A
    J Med Chem; 1988 Jul; 31(7):1463-6. PubMed ID: 3385735
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and 5-HT-3 receptor binding of 2- and 3-(halo)alkoxyl substituted (S)-N-(1-azabicyclo[2.2.2]oct-3-yl)-5-chlorobenzamides as potential radioligands.
    Hewlett WA; Schmidt DE; Mason NS; Trivedi BL; Ebert MH; de Paulis T
    Nucl Med Biol; 1998 Feb; 25(2):141-53. PubMed ID: 9468029
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Binding of radioiodinated SPECT ligands to transfected cell membranes expressing single muscarinic receptor subtypes.
    Zeeberg BR; Gitler MS; Baumgold J; de la Cruz RA; Reba RC
    Biochem Biophys Res Commun; 1991 Sep; 179(2):768-75. PubMed ID: 1898398
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.