BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 8464899)

  • 1. Antibody-promoted dimerization bypasses the regulation of DNA binding by the heme domain of the yeast transcriptional activator HAP1.
    Zhang L; Bermingham-McDonogh O; Turcotte B; Guarente L
    Proc Natl Acad Sci U S A; 1993 Apr; 90(7):2851-5. PubMed ID: 8464899
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The coiled coil dimerization element of the yeast transcriptional activator Hap1, a Gal4 family member, is dispensable for DNA binding but differentially affects transcriptional activation.
    Hach A; Hon T; Zhang L
    J Biol Chem; 2000 Jan; 275(1):248-54. PubMed ID: 10617612
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Multiple domains mediate heme control of the yeast activator HAP1.
    Haldi ML; Guarente L
    Mol Gen Genet; 1995 Jul; 248(2):229-35. PubMed ID: 7651346
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The heme activator protein Hap1 represses transcription by a heme-independent mechanism in Saccharomyces cerevisiae.
    Hon T; Lee HC; Hu Z; Iyer VR; Zhang L
    Genetics; 2005 Mar; 169(3):1343-52. PubMed ID: 15654089
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Functional analysis of the zinc cluster domain of the CYP1 (HAP1) complex regulator in heme-sufficient and heme-deficient yeast cells.
    Defranoux N; Gaisne M; Verdière J
    Mol Gen Genet; 1994 Mar; 242(6):699-707. PubMed ID: 8152420
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The yeast activator HAP1--a GAL4 family member--binds DNA in a directly repeated orientation.
    Zhang L; Guarente L
    Genes Dev; 1994 Sep; 8(17):2110-9. PubMed ID: 7958882
    [TBL] [Abstract][Full Text] [Related]  

  • 7. HAP1 is nuclear but is bound to a cellular factor in the absence of heme.
    Zhang L; Guarente L
    J Biol Chem; 1994 May; 269(20):14643-7. PubMed ID: 8182072
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The yeast heme-responsive transcriptional activator Hap1 is a preexisting dimer in the absence of heme.
    Hon T; Hach A; Tamalis D; Zhu Y; Zhang L
    J Biol Chem; 1999 Aug; 274(32):22770-4. PubMed ID: 10428861
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutations that alter transcriptional activation but not DNA binding in the zinc finger of yeast activator HAPI.
    Kim KS; Guarente L
    Nature; 1989 Nov; 342(6246):200-3. PubMed ID: 2509943
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Functional analysis of heme regulatory elements of the transcriptional activator Hap1.
    Hon T; Hach A; Lee HC; Cheng T; Zhang L
    Biochem Biophys Res Commun; 2000 Jul; 273(2):584-91. PubMed ID: 10873649
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Hsp70-Ydj1 molecular chaperone represses the activity of the heme activator protein Hap1 in the absence of heme.
    Hon T; Lee HC; Hach A; Johnson JL; Craig EA; Erdjument-Bromage H; Tempst P; Zhang L
    Mol Cell Biol; 2001 Dec; 21(23):7923-32. PubMed ID: 11689685
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 1H, 15N resonance assignment and three-dimensional structure of CYP1 (HAP1) DNA-binding domain.
    Timmerman J; Vuidepot AL; Bontems F; Lallemand JY; Gervais M; Shechter E; Guiard B
    J Mol Biol; 1996 Jun; 259(4):792-804. PubMed ID: 8683583
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Evidence that TUP1/SSN6 has a positive effect on the activity of the yeast activator HAP1.
    Zhang L; Guarente L
    Genetics; 1994 Mar; 136(3):813-7. PubMed ID: 8005436
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A novel allele of HAP1 causes uninducible expression of HEM13 in Saccharomyces cerevisiae.
    Ushinsky SC; Keng T
    Genetics; 1994 Mar; 136(3):819-31. PubMed ID: 8005437
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Internal deletions in the yeast transcriptional activator HAP1 have opposite effects at two sequence elements.
    Kim KS; Pfeifer K; Powell L; Guarente L
    Proc Natl Acad Sci U S A; 1990 Jun; 87(12):4524-8. PubMed ID: 2162046
    [TBL] [Abstract][Full Text] [Related]  

  • 16. HAP1 positive control mutants specific for one of two binding sites.
    Turcotte B; Guarente L
    Genes Dev; 1992 Oct; 6(10):2001-9. PubMed ID: 1327959
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NMR analysis of CYP1(HAP1) DNA binding domain-CYC1 upstream activation sequence interactions: recognition of a CGG trinucleotide and of an additional thymine 5 bp downstream by the zinc cluster and the N-terminal extremity of the protein.
    Vuidepot AL; Bontems F; Gervais M; Guiard B; Shechter E; Lallemand JY
    Nucleic Acids Res; 1997 Aug; 25(15):3042-50. PubMed ID: 9224603
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Control of Hap1-DNA site recognition through the interplay of multiple distinct intermolecular interactions.
    Wang LL; Denman I; Junker M
    Biochemistry; 2004 Nov; 43(43):13816-26. PubMed ID: 15504044
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evidence for an interaction between the CYP1(HAP1) activator and a cellular factor during heme-dependent transcriptional regulation in the yeast Saccharomyces cerevisiae.
    Fytlovich S; Gervais M; Agrimonti C; Guiard B
    EMBO J; 1993 Mar; 12(3):1209-18. PubMed ID: 8458333
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Functional dissection and sequence of yeast HAP1 activator.
    Pfeifer K; Kim KS; Kogan S; Guarente L
    Cell; 1989 Jan; 56(2):291-301. PubMed ID: 2643482
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.