These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

119 related articles for article (PubMed ID: 8467487)

  • 41. Enforced expression of wild-type p53 curtails the transcription of the O(6)-methylguanine-DNA methyltransferase gene in human tumor cells and enhances their sensitivity to alkylating agents.
    Srivenugopal KS; Shou J; Mullapudi SR; Lang FF; Rao JS; Ali-Osman F
    Clin Cancer Res; 2001 May; 7(5):1398-409. PubMed ID: 11350911
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Promoter hypermethylation and inactivation of O(6)-methylguanine-DNA methyltransferase in esophageal squamous cell carcinomas and its reactivation in cell lines.
    Fang MZ; Jin Z; Wang Y; Liao J; Yang GY; Wang LD; Yang CS
    Int J Oncol; 2005 Mar; 26(3):615-22. PubMed ID: 15703815
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Alteration of O6-methylguanine-DNA methyltransferase in colorectal neoplasms in sporadic and familial adenomatous polyposis patients.
    Kim SH; Bae SI; Lee HS; Kim WH
    Mol Carcinog; 2003 May; 37(1):32-8. PubMed ID: 12720298
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Promoter methylation of O(6)-methylguanine-DNA-methyltransferase in lung cancer is regulated by p53.
    Lai JC; Cheng YW; Goan YG; Chang JT; Wu TC; Chen CY; Lee H
    DNA Repair (Amst); 2008 Aug; 7(8):1352-63. PubMed ID: 18555750
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis.
    Esteller M; Risques RA; Toyota M; Capella G; Moreno V; Peinado MA; Baylin SB; Herman JG
    Cancer Res; 2001 Jun; 61(12):4689-92. PubMed ID: 11406538
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Prognostic significance of O6-methylguanine-DNA methyltransferase determined by promoter hypermethylation and immunohistochemical expression in anaplastic gliomas.
    Brell M; Tortosa A; Verger E; Gil JM; Viñolas N; Villá S; Acebes JJ; Caral L; Pujol T; Ferrer I; Ribalta T; Graus F
    Clin Cancer Res; 2005 Jul; 11(14):5167-74. PubMed ID: 16033832
    [TBL] [Abstract][Full Text] [Related]  

  • 47. O(6)-Methylguanine-DNA methyltransferase promoter hypermethylation shifts the p53 mutational spectrum in non-small cell lung cancer.
    Wolf P; Hu YC; Doffek K; Sidransky D; Ahrendt SA
    Cancer Res; 2001 Nov; 61(22):8113-7. PubMed ID: 11719438
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Inactivation of DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation and its relation to p53 mutations in esophageal squamous cell carcinoma.
    Zhang L; Lu W; Miao X; Xing D; Tan W; Lin D
    Carcinogenesis; 2003 Jun; 24(6):1039-44. PubMed ID: 12807758
    [TBL] [Abstract][Full Text] [Related]  

  • 49. [Inhibition of telomerase activity by ribozyme targeted to human telomerase transcriptase].
    Qu Y; Liu SQ; Peng WZ; Liu BL
    Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai); 2002 May; 34(3):323-8. PubMed ID: 12019445
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Hypermethylation of O6-methylguanine-DNA methyltransferase promoter may predict nonrecurrence after chemotherapy in colorectal cancer cases.
    Nagasaka T; Sharp GB; Notohara K; Kambara T; Sasamoto H; Isozaki H; MacPhee DG; Jass JR; Tanaka N; Matsubara N
    Clin Cancer Res; 2003 Nov; 9(14):5306-12. PubMed ID: 14614014
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Characterisation of a P140K mutant O6-methylguanine-DNA-methyltransferase (MGMT)-expressing transgenic mouse line with drug-selectable bone marrow.
    Kramer BA; Lemckert FA; Alexander IE; Gunning PW; McCowage GB
    J Gene Med; 2006 Sep; 8(9):1071-85. PubMed ID: 16927363
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Targeting of O6-methylguanine-DNA methyltransferase (MGMT) activity by antimessenger oligonucleotide sensitizes CHO/Mex+ transfected cells to mitozolomide.
    Citti L; Boldrini L; Preuss I; Kaina B; Mariani L; Rainaldi G
    Carcinogenesis; 1996 Jan; 17(1):25-9. PubMed ID: 8565132
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Detection of O6-methylguanine-DNA methyltransferase-expression in human tumors by means of in situ hybridization.
    Eberhagen I; Bankmann M; Kaina B
    Anticancer Res; 1995; 15(3):761-7. PubMed ID: 7645955
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Graded methylation in the promoter and body of the O6-methylguanine DNA methyltransferase (MGMT) gene correlates with MGMT expression in human glioma cells.
    Costello JF; Futscher BW; Tano K; Graunke DM; Pieper RO
    J Biol Chem; 1994 Jun; 269(25):17228-37. PubMed ID: 8006031
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Production and characterization of antipeptide antibodies against human O6-methylguanine-DNA methyltransferase.
    Ostrowski LE; Pegram CN; Von Wronski MA; Humphrey PA; He XM; Shiota S; Mitra S; Brent TP; Bigner DD
    Cancer Res; 1991 Jul; 51(13):3339-44. PubMed ID: 2054774
    [TBL] [Abstract][Full Text] [Related]  

  • 56. In vitro methylation of the human O6-methylguanine-DNA methyltransferase promoter reduces transcription.
    Harris LC; Remack JS; Brent TP
    Biochim Biophys Acta; 1994 Mar; 1217(2):141-6. PubMed ID: 8110828
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Comparison of O-6-methylguanine DNA methyltransferase (MGMT) mRNA levels in Mer+ and Mer- human tumor cell lines containing the MGMT gene by the polymerase chain reaction technique.
    Pieper RO; Futscher BW; Dong Q; Ellis TM; Erickson LC
    Cancer Commun; 1990; 2(1):13-20. PubMed ID: 2369549
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Intracellular localization of human DNA repair enzyme methylguanine-DNA methyltransferase by antibodies and its importance.
    Ayi TC; Loh KC; Ali RB; Li BF
    Cancer Res; 1992 Dec; 52(23):6423-30. PubMed ID: 1384961
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Expression of the O6-methylguanine-DNA methyltransferase gene in eight human tumor cell lines.
    Chen J; Zhang Y; Wu Y
    Chin Med Sci J; 1994 Sep; 9(3):143-6. PubMed ID: 7865832
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Transient transfection of a synthetic hammerhead ribozyme targeted against human MGMT gene to cells in culture potentiates the genotoxicity of the alkylation damage induced by mitozolomide.
    Citti L; Eckstein F; Capecchi B; Mariani L; Nevischi S; Poggi A; Rainaldi G
    Antisense Nucleic Acid Drug Dev; 1999 Apr; 9(2):125-33. PubMed ID: 10355819
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.