BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

458 related articles for article (PubMed ID: 8471029)

  • 1. 4-Chloro-3-hydroxyanthranilate, 6-chlorotryptophan and norharmane attenuate quinolinic acid formation by interferon-gamma-stimulated monocytes (THP-1 cells).
    Saito K; Chen CY; Masana M; Crowley JS; Markey SP; Heyes MP
    Biochem J; 1993 Apr; 291 ( Pt 1)(Pt 1):11-4. PubMed ID: 8471029
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A mechanism of quinolinic acid formation by brain in inflammatory neurological disease. Attenuation of synthesis from L-tryptophan by 6-chlorotryptophan and 4-chloro-3-hydroxyanthranilate.
    Heyes MP; Saito K; Major EO; Milstien S; Markey SP; Vickers JH
    Brain; 1993 Dec; 116 ( Pt 6)():1425-50. PubMed ID: 8293279
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Metabolism of L-tryptophan to kynurenate and quinolinate in the central nervous system: effects of 6-chlorotryptophan and 4-chloro-3-hydroxyanthranilate.
    Naritsin DB; Saito K; Markey SP; Chen CY; Heyes MP
    J Neurochem; 1995 Nov; 65(5):2217-26. PubMed ID: 7595510
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Different kynurenine pathway enzymes limit quinolinic acid formation by various human cell types.
    Heyes MP; Chen CY; Major EO; Saito K
    Biochem J; 1997 Sep; 326 ( Pt 2)(Pt 2):351-6. PubMed ID: 9291104
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 6-Chloro-D,L-tryptophan, 4-chloro-3-hydroxyanthranilate and dexamethasone attenuate quinolinic acid accumulation in brain and blood following systemic immune activation.
    Saito K; Markey SP; Heyes MP
    Neurosci Lett; 1994 Sep; 178(2):211-5. PubMed ID: 7824198
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human microglia convert l-tryptophan into the neurotoxin quinolinic acid.
    Heyes MP; Achim CL; Wiley CA; Major EO; Saito K; Markey SP
    Biochem J; 1996 Dec; 320 ( Pt 2)(Pt 2):595-7. PubMed ID: 8973572
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effects of immune activation on quinolinic acid and neuroactive kynurenines in the mouse.
    Saito K; Markey SP; Heyes MP
    Neuroscience; 1992 Nov; 51(1):25-39. PubMed ID: 1465184
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Kynurenine pathway enzymes in brain: responses to ischemic brain injury versus systemic immune activation.
    Saito K; Nowak TS; Suyama K; Quearry BJ; Saito M; Crowley JS; Markey SP; Heyes MP
    J Neurochem; 1993 Dec; 61(6):2061-70. PubMed ID: 8245962
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanism of delayed increases in kynurenine pathway metabolism in damaged brain regions following transient cerebral ischemia.
    Saito K; Nowak TS; Markey SP; Heyes MP
    J Neurochem; 1993 Jan; 60(1):180-92. PubMed ID: 8417138
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 4-chloro-3-hydroxyanthranilate attenuate quinolinic acid accumulation in brain following transient cerebral ischemia in the gerbil.
    Saito K; Seishima M; Noma A; Suyama K; Markey SP; Heyes MP
    Adv Exp Med Biol; 1996; 398():407-11. PubMed ID: 8906296
    [No Abstract]   [Full Text] [Related]  

  • 11. Regulation of the kynurenine metabolic pathway by interferon-gamma in murine cloned macrophages and microglial cells.
    Alberati-Giani D; Ricciardi-Castagnoli P; Köhler C; Cesura AM
    J Neurochem; 1996 Mar; 66(3):996-1004. PubMed ID: 8769859
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Poliovirus induces indoleamine-2,3-dioxygenase and quinolinic acid synthesis in macaque brain.
    Heyes MP; Saito K; Jacobowitz D; Markey SP; Takikawa O; Vickers JH
    FASEB J; 1992 Aug; 6(11):2977-89. PubMed ID: 1322853
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 3-Hydroxyanthranilic acid, an L-tryptophan metabolite, induces apoptosis in monocyte-derived cells stimulated by interferon-gamma.
    Morita T; Saito K; Takemura M; Maekawa N; Fujigaki S; Fujii H; Wada H; Takeuchi S; Noma A; Seishima M
    Ann Clin Biochem; 2001 May; 38(Pt 3):242-51. PubMed ID: 11392499
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A mechanism for increased quinolinic acid formation following acute systemic immune stimulation.
    Saito K; Crowley JS; Markey SP; Heyes MP
    J Biol Chem; 1993 Jul; 268(21):15496-503. PubMed ID: 8340378
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 3-Hydroxyanthranilic acid accumulation following administration of the 3-hydroxyanthranilic acid 3,4-dioxygenase inhibitor NCR-631.
    Fornstedt-Wallin B; Lundström J; Fredriksson G; Schwarcz R; Luthman J
    Eur J Pharmacol; 1999 Dec; 386(1):15-24. PubMed ID: 10611459
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tryptophan and glucose metabolism in rat liver cells. The effects of DL-6-chlorotryptophan, 4-chloro-3-hydroxyanthranilate and pyrazinamide.
    Cook JS; Pogson CI
    Biochem J; 1983 Aug; 214(2):511-6. PubMed ID: 6688524
    [TBL] [Abstract][Full Text] [Related]  

  • 17. L-tryptophan-kynurenine pathway metabolite 3-hydroxyanthranilic acid induces apoptosis in macrophage-derived cells under pathophysiological conditions.
    Morita T; Saito K; Takemura M; Maekawa N; Fujigaki S; Fujii H; Wada H; Takeuchi S; Noma A; Seishima M
    Adv Exp Med Biol; 1999; 467():559-63. PubMed ID: 10721100
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combined inhibition of indoleamine 2,3-dioxygenase and nitric oxide synthase modulates neurotoxin release by interferon-gamma-activated macrophages.
    Chiarugi A; Dello Sbarba P; Paccagnini A; Donnini S; Filippi S; Moroni F
    J Leukoc Biol; 2000 Aug; 68(2):260-6. PubMed ID: 10947071
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of systemic and central nervous system localized inflammation on the contributions of metabolic precursors to the L-kynurenine and quinolinic acid pools in brain.
    Kita T; Morrison PF; Heyes MP; Markey SP
    J Neurochem; 2002 Jul; 82(2):258-68. PubMed ID: 12124427
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The immune effects of TRYCATs (tryptophan catabolites along the IDO pathway): relevance for depression - and other conditions characterized by tryptophan depletion induced by inflammation.
    Maes M; Mihaylova I; Ruyter MD; Kubera M; Bosmans E
    Neuro Endocrinol Lett; 2007 Dec; 28(6):826-31. PubMed ID: 18063923
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.