These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 8474430)

  • 1. Identification of residues important for ligand binding to the human 5-hydroxytryptamine1A serotonin receptor.
    Chanda PK; Minchin MC; Davis AR; Greenberg L; Reilly Y; McGregor WH; Bhat R; Lubeck MD; Mizutani S; Hung PP
    Mol Pharmacol; 1993 Apr; 43(4):516-20. PubMed ID: 8474430
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human gene S31 encodes the pharmacologically defined serotonin 5-hydroxytryptamine1E receptor.
    Zgombick JM; Schechter LE; Macchi M; Hartig PR; Branchek TA; Weinshank RL
    Mol Pharmacol; 1992 Aug; 42(2):180-5. PubMed ID: 1513320
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutagenesis analysis of the serotonin 5-HT2C receptor and a Caenorhabditis elegans 5-HT2 homologue: conserved residues of helix 4 and helix 7 contribute to agonist-dependent activation of 5-HT2 receptors.
    Xie J; Dernovici S; Ribeiro P
    J Neurochem; 2005 Jan; 92(2):375-87. PubMed ID: 15663485
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of a single amino acid residue responsible for the binding of a class of beta-adrenergic receptor antagonists to 5-hydroxytryptamine1A receptors.
    Guan XM; Peroutka SJ; Kobilka BK
    Mol Pharmacol; 1992 Apr; 41(4):695-8. PubMed ID: 1349154
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 5-HT1A-versus D2-receptor selectivity of flesinoxan and analogous N4-substituted N1-arylpiperazines.
    Kuipers W; Kruse CG; van Wijngaarden I; Standaar PJ; Tulp MT; Veldman N; Spek AL; IJzerman AP
    J Med Chem; 1997 Jan; 40(3):300-12. PubMed ID: 9022796
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Binding sites and transduction process of the cholecystokininB receptor: involvement of highly conserved aromatic residues of the transmembrane domains evidenced by site-directed mutagenesis.
    Jagerschmidt A; Guillaume N; Roques BP; Noble F
    Mol Pharmacol; 1998 May; 53(5):878-85. PubMed ID: 9584214
    [TBL] [Abstract][Full Text] [Related]  

  • 7. An aspartate residue at the extracellular boundary of TMII and an arginine residue in TMVII of the gastrin-releasing peptide receptor interact to facilitate heterotrimeric G protein coupling.
    Donohue PJ; Sainz E; Akeson M; Kroog GS; Mantey SA; Battey JF; Jensen RT; Northup JK
    Biochemistry; 1999 Jul; 38(29):9366-72. PubMed ID: 10413511
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Contribution of a helix 5 locus to selectivity of hallucinogenic and nonhallucinogenic ligands for the human 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptors: direct and indirect effects on ligand affinity mediated by the same locus.
    Almaula N; Ebersole BJ; Ballesteros JA; Weinstein H; Sealfon SC
    Mol Pharmacol; 1996 Jul; 50(1):34-42. PubMed ID: 8700116
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutant 5-hydroxytryptamine 1A receptor D116A is a receptor activated solely by synthetic ligands with a rich pharmacology.
    Cussac D; Palmier C; Finana F; De Vries L; Tardif S; Léger C; Bernois S; Heusler P
    J Pharmacol Exp Ther; 2009 Oct; 331(1):222-33. PubMed ID: 19605522
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differences in the central nervous system distribution and pharmacology of the mouse 5-hydroxytryptamine-6 receptor compared with rat and human receptors investigated by radioligand binding, site-directed mutagenesis, and molecular modeling.
    Hirst WD; Abrahamsen B; Blaney FE; Calver AR; Aloj L; Price GW; Medhurst AD
    Mol Pharmacol; 2003 Dec; 64(6):1295-308. PubMed ID: 14645659
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cysteine residues are involved in structure and function of melanocortin 1 receptor: Substitution of a cysteine residue in transmembrane segment two converts an agonist to antagonist.
    Frändberg PA; Doufexis M; Kapas S; Chhajlani V
    Biochem Biophys Res Commun; 2001 Mar; 281(4):851-7. PubMed ID: 11237737
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activation of constitutive 5-hydroxytryptamine(1B) receptor by a series of mutations in the BBXXB motif: positioning of the third intracellular loop distal junction and its G(o)alpha protein interactions.
    Pauwels PJ; Gouble A; Wurch T
    Biochem J; 1999 Oct; 343 Pt 2(Pt 2):435-42. PubMed ID: 10510311
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The ligand binding site of the formyl peptide receptor maps in the transmembrane region.
    Miettinen HM; Mills JS; Gripentrog JM; Dratz EA; Granger BL; Jesaitis AJ
    J Immunol; 1997 Oct; 159(8):4045-54. PubMed ID: 9378994
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of amino acid residues in transmembrane helices VI and VII of the lutropin/choriogonadotropin receptor involved in signaling.
    Fernandez LM; Puett D
    Biochemistry; 1996 Apr; 35(13):3986-93. PubMed ID: 8672431
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Functional significance of the BBXXB motif reversed present in the cytoplasmic domains of the human follicle-stimulating hormone receptor.
    Timossi C; Ortiz-Elizondo C; Pineda DB; Dias JA; Conn PM; Ulloa-Aguirre A
    Mol Cell Endocrinol; 2004 Aug; 223(1-2):17-26. PubMed ID: 15279907
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Charged residues of the conserved DRY triplet of the vasopressin V1a receptor provide molecular determinants for cell surface delivery and internalization.
    Hawtin SR
    Mol Pharmacol; 2005 Oct; 68(4):1172-82. PubMed ID: 16049168
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Altered ligand dissociation rates in thyrotropin-releasing hormone receptors mutated in glutamine 105 of transmembrane helix III.
    del Camino D; Barros F; Pardo LA; de la Peña P
    Biochemistry; 1997 Mar; 36(11):3308-18. PubMed ID: 9116009
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Delineation of the peptide binding site of the human galanin receptor.
    Kask K; Berthold M; Kahl U; Nordvall G; Bartfai T
    EMBO J; 1996 Jan; 15(2):236-44. PubMed ID: 8617199
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutagenesis of the human 5-HT1B receptor: differences from the closely related 5-HT1A receptor and the role of residue F331 in signal transduction.
    Grånäs C; Nordvall G; Larhammar D
    J Recept Signal Transduct Res; 1998; 18(4-6):225-41. PubMed ID: 9879059
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Selected cysteine residues in transmembrane domains of mu-opioid receptor are critical for effects of sulfhydryl reagents.
    Deng HB; Guang W; Wang JB
    J Pharmacol Exp Ther; 2000 Apr; 293(1):113-20. PubMed ID: 10734160
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.