BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

283 related articles for article (PubMed ID: 8474431)

  • 1. Regulation of thymidylate synthase in human colon cancer cells treated with 5-fluorouracil and interferon-gamma.
    Chu E; Koeller DM; Johnston PG; Zinn S; Allegra CJ
    Mol Pharmacol; 1993 Apr; 43(4):527-33. PubMed ID: 8474431
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Interaction of gamma interferon and 5-fluorouracil in the H630 human colon carcinoma cell line.
    Chu E; Zinn S; Boarman D; Allegra CJ
    Cancer Res; 1990 Sep; 50(18):5834-40. PubMed ID: 1697502
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Induction of thymidylate synthase associated with multidrug resistance in human breast and colon cancer cell lines.
    Chu E; Drake JC; Koeller DM; Zinn S; Jamis-Dow CA; Yeh GC; Allegra CJ
    Mol Pharmacol; 1991 Feb; 39(2):136-43. PubMed ID: 1704999
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Immunological quantitation of thymidylate synthase using the monoclonal antibody TS 106 in 5-fluorouracil-sensitive and -resistant human cancer cell lines.
    Johnston PG; Drake JC; Trepel J; Allegra CJ
    Cancer Res; 1992 Aug; 52(16):4306-12. PubMed ID: 1643628
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cell cycle regulation of the G0/G1 transition in 5-fluorouracil-sensitive and -resistant human colon cancer cell lines.
    McGinn CJ; Pestalozzi BC; Drake JC; Glennon MC; Kunugi K; Otterson G; Allegra CJ; Johnston PG; Kinsella TJ
    Cancer J; 2000; 6(4):234-42. PubMed ID: 11038143
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The role of thymidylate synthase induction in modulating p53-regulated gene expression in response to 5-fluorouracil and antifolates.
    Longley DB; Boyer J; Allen WL; Latif T; Ferguson PR; Maxwell PJ; McDermott U; Lynch M; Harkin DP; Johnston PG
    Cancer Res; 2002 May; 62(9):2644-9. PubMed ID: 11980662
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regulation of p53 expression in response to 5-fluorouracil in human cancer RKO cells.
    Ju J; Schmitz JC; Song B; Kudo K; Chu E
    Clin Cancer Res; 2007 Jul; 13(14):4245-51. PubMed ID: 17634554
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Chronic exposure of colorectal cancer cells in culture to fluoropyrimidine analogs induces thymidylate synthase and suppresses p53. A molecular explanation for the mechanism of 5-FU resistance.
    Subbarayan PR; Sarkar M; Nelson G; Benitez E; Singhal S; Ardalan B
    Anticancer Res; 2010 Apr; 30(4):1149-56. PubMed ID: 20530421
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Detection and quantitation of thymidylate synthase mRNA in human colon adenocarcinoma cell line resistant to 5-fluorouracil by competitive PCR.
    Shibata J; Aiba K; Shibata H; Minowa S; Horikoshi N
    Anticancer Res; 1998; 18(3A):1457-63. PubMed ID: 9673356
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Multi-level gene expression profiles affected by thymidylate synthase and 5-fluorouracil in colon cancer.
    Xi Y; Nakajima G; Schmitz JC; Chu E; Ju J
    BMC Genomics; 2006 Apr; 7():68. PubMed ID: 16584549
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Thymidylate synthase gene amplification in human colon cancer cell lines resistant to 5-fluorouracil.
    Copur S; Aiba K; Drake JC; Allegra CJ; Chu E
    Biochem Pharmacol; 1995 May; 49(10):1419-26. PubMed ID: 7763285
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dihydropyrimidine dehydrogenase but not thymidylate synthase expression is associated with resistance to 5-fluorouracil in colorectal cancer.
    Nita ME; Tominaga O; Nagawa H; Tsuruo T; Muto T
    Hepatogastroenterology; 1998; 45(24):2117-22. PubMed ID: 9951876
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Enhancement of 5-fluorouracil sensitivity by an rTS signaling mimic in H630 colon cancer cells.
    Dolnick R; Wu Q; Angelino NJ; Stephanie LV; Chow KC; Sufrin JR; Dolnick BJ
    Cancer Res; 2005 Jul; 65(13):5917-24. PubMed ID: 15994970
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differential regulation of carcinoembryonic antigen and biliary glycoprotein by gamma-interferon.
    Takahashi H; Okai Y; Paxton RJ; Hefta LJ; Shively JE
    Cancer Res; 1993 Apr; 53(7):1612-9. PubMed ID: 8453631
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Determinants of cytotoxicity with prolonged exposure to fluorouracil in human colon cancer cells.
    Ren Q; Van Groeningen CJ; Hardcastle A; Aherne GW; Geoffroy F; Allegra CJ; Johnston PG; Grem JL
    Oncol Res; 1997; 9(2):77-88. PubMed ID: 9167189
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interferon beta increases antitumor activity of 5-fluorouracil against human colon carcinoma cells in vitro and in vivo.
    Kase S; Kubota T; Watanabe M; Furukawa T; Tanino H; Ishibiki K; Teramoto T; Kitajima M
    Anticancer Res; 1993; 13(2):369-73. PubMed ID: 8517649
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The transfection of thymidylate synthase antisense suppresses oncogenic properties of a human colon cancer cell line and augments the antitumor effect of fluorouracil.
    Matsuoka K; Tsukuda K; Suda M; Kobayashi K; Ota T; Okita A; Watanabe K; Suzuki E; Murakami M; Doihara H; Shimizu N
    Int J Oncol; 2004 Jan; 24(1):217-22. PubMed ID: 14654960
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Prolonged and enhanced suppression of thymidylate synthase by weekly 24-h infusion of high-dose 5-fluorouracil.
    Yeh KH; Yeh SH; Hsu CH; Wang TM; Ma IF; Cheng AL
    Br J Cancer; 2000 Dec; 83(11):1510-5. PubMed ID: 11076661
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacogenomic dissection of resistance to thymidylate synthase inhibitors.
    Wang W; Marsh S; Cassidy J; McLeod HL
    Cancer Res; 2001 Jul; 61(14):5505-10. PubMed ID: 11454699
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of the combined treatment with 5-fluorouracil, gamma-interferon or folinic acid on carcinoembryonic antigen expression in colon cancer cells.
    Aquino A; Prete SP; Greiner JW; Giuliani A; Graziani G; Turriziani M; De Filippi R; Masci G; Bonmassar E; De Vecchis L
    Clin Cancer Res; 1998 Oct; 4(10):2473-81. PubMed ID: 9796980
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.