BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

464 related articles for article (PubMed ID: 8479541)

  • 1. Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling.
    Li N; Batzer A; Daly R; Yajnik V; Skolnik E; Chardin P; Bar-Sagi D; Margolis B; Schlessinger J
    Nature; 1993 May; 363(6424):85-8. PubMed ID: 8479541
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1.
    Rozakis-Adcock M; Fernley R; Wade J; Pawson T; Bowtell D
    Nature; 1993 May; 363(6424):83-5. PubMed ID: 8479540
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras.
    Gale NW; Kaplan S; Lowenstein EJ; Schlessinger J; Bar-Sagi D
    Nature; 1993 May; 363(6424):88-92. PubMed ID: 8386805
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation.
    Egan SE; Giddings BW; Brooks MW; Buday L; Sizeland AM; Weinberg RA
    Nature; 1993 May; 363(6424):45-51. PubMed ID: 8479536
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Coupling of the murine protein tyrosine phosphatase PEST to the epidermal growth factor (EGF) receptor through a Src homology 3 (SH3) domain-mediated association with Grb2.
    Charest A; Wagner J; Kwan M; Tremblay ML
    Oncogene; 1997 Apr; 14(14):1643-51. PubMed ID: 9135065
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A Grb2-associated docking protein in EGF- and insulin-receptor signalling.
    Holgado-Madruga M; Emlet DR; Moscatello DK; Godwin AK; Wong AJ
    Nature; 1996 Feb; 379(6565):560-4. PubMed ID: 8596638
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Grb2 regulates Stat3 activation negatively in epidermal growth factor signalling.
    Zhang T; Ma J; Cao X
    Biochem J; 2003 Dec; 376(Pt 2):457-64. PubMed ID: 14498832
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Autophosphorylation mutants of the EGF-receptor signal through auxiliary mechanisms involving SH2 domain proteins.
    Li N; Schlessinger J; Margolis B
    Oncogene; 1994 Dec; 9(12):3457-65. PubMed ID: 7970705
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sos1 rapidly associates with Grb2 and is hypophosphorylated when complexed with the EGF receptor after EGF stimulation.
    Hu Y; Bowtell DD
    Oncogene; 1996 May; 12(9):1865-72. PubMed ID: 8649846
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phosphorylation of growth factor receptor binding protein-2 by pp60c-src tyrosine kinase.
    Jones DA; Benjamin CW
    Arch Biochem Biophys; 1997 Jan; 337(2):143-8. PubMed ID: 9016807
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases.
    Rozakis-Adcock M; McGlade J; Mbamalu G; Pelicci G; Daly R; Li W; Batzer A; Thomas S; Brugge J; Pelicci PG; Schlessinger J; Pawson T
    Nature; 1992 Dec; 360(6405):689-92. PubMed ID: 1465135
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Grb2 regulation of the actin-based cytoskeleton is required for ligand-independent EGF receptor-mediated oncogenesis.
    Boerner JL; Danielsen AJ; Lovejoy CA; Wang Z; Juneja SC; Faupel-Badger JM; Darce JR; Maihle NJ
    Oncogene; 2003 Oct; 22(43):6679-89. PubMed ID: 14555981
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activation of tyrosine kinases by alpha1A-adrenergic and growth factor receptors in transfected PC12 cells.
    Zhong H; Minneman KP
    Biochem J; 1999 Dec; 344 Pt 3(Pt 3):889-94. PubMed ID: 10585878
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of the Ras signalling pathway in human breast cancer cells overexpressing erbB-2.
    Janes PW; Daly RJ; deFazio A; Sutherland RL
    Oncogene; 1994 Dec; 9(12):3601-8. PubMed ID: 7970720
    [TBL] [Abstract][Full Text] [Related]  

  • 15. N-Shc: a neural-specific adapter molecule that mediates signaling from neurotrophin/Trk to Ras/MAPK pathway.
    Nakamura T; Sanokawa R; Sasaki Y; Ayusawa D; Oishi M; Mori N
    Oncogene; 1996 Sep; 13(6):1111-21. PubMed ID: 8808684
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor.
    Nioche P; Liu WQ; Broutin I; Charbonnier F; Latreille MT; Vidal M; Roques B; Garbay C; Ducruix A
    J Mol Biol; 2002 Feb; 315(5):1167-77. PubMed ID: 11827484
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A new function for phospholipase C-gamma1: coupling to the adaptor protein GRB2.
    Pei Z; Maloney JA; Yang L; Williamson JR
    Arch Biochem Biophys; 1997 Sep; 345(1):103-10. PubMed ID: 9281317
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SH2 domain specificity and activity modified by a single residue.
    Marengere LE; Songyang Z; Gish GD; Schaller MD; Parsons JT; Stern MJ; Cantley LC; Pawson T
    Nature; 1994 Jun; 369(6480):502-5. PubMed ID: 7515480
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential response of the Ras exchange factor, Ras-GRF to tyrosine kinase and G protein mediated signals.
    Shou C; Wurmser A; Suen KL; Barbacid M; Feig LA; Ling K
    Oncogene; 1995 May; 10(10):1887-93. PubMed ID: 7761090
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tyrosine kinase signalling pathways.
    Pawson T
    Princess Takamatsu Symp; 1994; 24():303-22. PubMed ID: 8983084
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.