BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

190 related articles for article (PubMed ID: 8481905)

  • 1. Roles of human hepatic and pulmonary cytochrome P450 enzymes in the metabolism of the environmental carcinogen 6-nitrochrysene.
    Chae YH; Yun CH; Guengerich FP; Kadlubar FF; el-Bayoumy K
    Cancer Res; 1993 May; 53(9):2028-34. PubMed ID: 8481905
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolism of 5-methylchrysene and 6-methylchrysene by human hepatic and pulmonary cytochrome P450 enzymes.
    Koehl W; Amin S; Staretz ME; Ueng YF; Yamazaki H; Tateishi T; Guengerich FP; Hecht SS
    Cancer Res; 1996 Jan; 56(2):316-24. PubMed ID: 8542586
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Metabolic activation of 6-nitrochrysene in explants of human bronchus and in isolated rat hepatocytes.
    Delclos KB; el-Bayoumy K; Casciano DA; Walker RP; Kadlubar FF; Hecht SS; Shivapurkar N; Mandal S; Stoner GD
    Cancer Res; 1989 Jun; 49(11):2909-13. PubMed ID: 2720650
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of trans-1,2-dihydro-1,2-dihydroxy-6-nitrochrysene as a major mutagenic metabolite of 6-nitrochrysene.
    El-Bayoumy K; Hecht SS
    Cancer Res; 1984 Aug; 44(8):3408-13. PubMed ID: 6378368
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1.
    Shimada T; Hayes CL; Yamazaki H; Amin S; Hecht SS; Guengerich FP; Sutter TR
    Cancer Res; 1996 Jul; 56(13):2979-84. PubMed ID: 8674051
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of trans-1,2-dihydro-1,2-dihydroxy-6-aminochrysene to genotoxic metabolites by rat and human cytochromes P450.
    Yamazaki H; Mimura M; Oda Y; Gonzalez FJ; el-Bayoumy K; Chae YH; Guengerich FP; Shimada T
    Carcinogenesis; 1994 Mar; 15(3):465-70. PubMed ID: 8118930
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Comparative metabolism of 1-, 2-, and 4-nitropyrene by human hepatic and pulmonary microsomes.
    Chae YH; Thomas T; Guengerich FP; Fu PP; El-Bayoumy K
    Cancer Res; 1999 Apr; 59(7):1473-80. PubMed ID: 10197616
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The role of intestinal microflora in the metabolic activation of 6-nitrochrysene to DNA-binding derivatives in mice.
    Delclos KB; Cerniglia CE; Dooley KL; Campbell WL; Franklin W; Walker RP
    Toxicology; 1990; 60(1-2):137-50. PubMed ID: 2315936
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Roles of individual human cytochrome P-450 enzymes in the bioactivation of benzo(a)pyrene, 7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene, and other dihydrodiol derivatives of polycyclic aromatic hydrocarbons.
    Shimada T; Martin MV; Pruess-Schwartz D; Marnett LJ; Guengerich FP
    Cancer Res; 1989 Nov; 49(22):6304-12. PubMed ID: 2509067
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Comparative tumorigenicity of 6-nitrochrysene and its metabolites in newborn mice.
    el-Bayoumy K; Shiue GH; Hecht SS
    Carcinogenesis; 1989 Feb; 10(2):369-72. PubMed ID: 2912588
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of 6-aminochrysene to genotoxic products by different forms of rat liver cytochrome P450 in an O-acetyltransferase-overexpressing Salmonella typhimurium strain (NM2009).
    Yamazaki H; Shimada T
    Biochem Pharmacol; 1992 Sep; 44(5):913-20. PubMed ID: 1530660
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of 5-(deoxyguanosin-N2-yl)- 1,2-dihydroxy-1,2-dihydro-6-aminochrysene as the major DNA lesion in the mammary gland of rats treated with the environmental pollutant 6-nitrochrysene.
    El-Bayoumy K; Sharma AK; Lin JM; Krzeminski J; Boyiri T; King LC; Lambert G; Padgett W; Nesnow S; Amin S
    Chem Res Toxicol; 2004 Dec; 17(12):1591-9. PubMed ID: 15606134
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Roles of different forms of cytochrome P450 in the activation of the promutagen 6-aminochrysene to genotoxic metabolites in human liver microsomes.
    Yamazaki H; Mimura M; Oda Y; Inui Y; Shiraga T; Iwasaki K; Guengerich FP; Shimada T
    Carcinogenesis; 1993 Jul; 14(7):1271-8. PubMed ID: 8330339
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Enzymes involved in the metabolism of the carcinogen 2-nitroanisole: evidence for its oxidative detoxication by human cytochromes P450.
    Miksanová M; Sulc M; Rýdlová H; Schmeiser HH; Frei E; Stiborová M
    Chem Res Toxicol; 2004 May; 17(5):663-71. PubMed ID: 15144223
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutagenicity, metabolism and DNA adduct formation of 6-nitrochrysene in Salmonella typhimurium.
    el-Bayoumy K; Delclos KB; Heflich RH; Walker R; Shiue GH; Hecht SS
    Mutagenesis; 1989 May; 4(3):235-40. PubMed ID: 2659942
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Metabolism of the carcinogen [3H]6-nitrochrysene in the preweanling mouse: identification of 6-aminochrysene-1,2-dihydrodiol as the probable proximate carcinogenic metabolite.
    Delclos KB; el-Bayoumy K; Hecht SS; Walker RP; Kadlubar FF
    Carcinogenesis; 1988 Oct; 9(10):1875-84. PubMed ID: 3168165
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Stereoselective metabolism of the environmental mammary carcinogen 6-nitrochrysene to trans-1,2-dihydroxy-1,2-dihydro-6-nitrochrysene by aroclor 1254-treated rat liver microsomes and their comparative mutation profiles in a laci mammary epithelial cell line.
    Sun YW; Guttenplan JB; Khmelnitsky M; Krzeminski J; Boyiri T; Amin S; El-Bayoumy K
    Chem Res Toxicol; 2009 Dec; 22(12):1992-7. PubMed ID: 19886636
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metabolism and DNA binding of the environmental colon carcinogen 6-nitrochrysene in rats.
    Chae YH; Delclos KB; Blaydes B; el-Bayoumy K
    Cancer Res; 1996 May; 56(9):2052-8. PubMed ID: 8616850
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Metabolic activation of the potent carcinogen dibenzo[a,l]pyrene by human recombinant cytochromes P450, lung and liver microsomes.
    Shou M; Krausz KW; Gonzalez FJ; Gelboin HV
    Carcinogenesis; 1996 Nov; 17(11):2429-33. PubMed ID: 8968059
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Metabolism and DNA binding of the environmental pollutant 6-nitrochrysene in primary culture of human breast cells and in cultured MCF-10A, MCF-7 and MDA-MB-435s cell lines.
    Boyiri T; Leszczynska J; Desai D; Amin S; Nixon DW; El-Bayoumy K
    Int J Cancer; 2002 Aug; 100(4):395-400. PubMed ID: 12115519
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.