These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

92 related articles for article (PubMed ID: 8484769)

  • 1. Biotransformation of pravastatin sodium (I). Mechanisms of enzymic transformation and epimerization of an allylic hydroxy group of pravastatin sodium.
    Kitazawa E; Tamura N; Iwabuchi H; Uchiyama M; Muramatsu S; Takahagi H; Tanaka M
    Biochem Biophys Res Commun; 1993 Apr; 192(2):597-602. PubMed ID: 8484769
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Comparison of cytochrome P-450-dependent metabolism and drug interactions of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors lovastatin and pravastatin in the liver.
    Jacobsen W; Kirchner G; Hallensleben K; Mancinelli L; Deters M; Hackbarth I; Benet LZ; Sewing KF; Christians U
    Drug Metab Dispos; 1999 Feb; 27(2):173-9. PubMed ID: 9929499
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Small intestinal metabolism of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor lovastatin and comparison with pravastatin.
    Jacobsen W; Kirchner G; Hallensleben K; Mancinelli L; Deters M; Hackbarth I; Baner K; Benet LZ; Sewing KF; Christians U
    J Pharmacol Exp Ther; 1999 Oct; 291(1):131-9. PubMed ID: 10490896
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Metabolism of pravastatin sodium by 3 alpha-hydroxysteroid dehydrogenase.
    Muramatsu S; Komokata Y; Tanaka Y; Takahagi H
    Biol Pharm Bull; 1997 Nov; 20(11):1199-203. PubMed ID: 9401732
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Quantification of pravastatin acid, lactone and isomers in human plasma by UHPLC-MS/MS and its application to a pediatric pharmacokinetic study.
    van Haandel L; Gibson KT; Leeder JS; Wagner JB
    J Chromatogr B Analyt Technol Biomed Life Sci; 2016 Feb; 1012-1013():169-77. PubMed ID: 26849185
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metabolism of pravastatin sodium in isolated rat hepatocytes. I. Glutathione conjugate formation reaction.
    Muramatsu S; Miyaguchi K; Iwabuchi H; Matsushita Y; Nakamura T; Kinoshita T; Tanaka M; Takahagi H
    Xenobiotica; 1992 May; 22(5):487-98. PubMed ID: 1413864
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Bioactivation of 3-n-butylphthalide via sulfation of its major metabolite 3-hydroxy-NBP: mediated mainly by sulfotransferase 1A1.
    Diao X; Pang X; Xie C; Guo Z; Zhong D; Chen X
    Drug Metab Dispos; 2014 Apr; 42(4):774-81. PubMed ID: 24468743
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tissue-selective action of pravastatin due to hepatocellular uptake via a sodium-independent bile acid transporter.
    Ziegler K; Stünkel W
    Biochim Biophys Acta; 1992 Jul; 1139(3):203-9. PubMed ID: 1627658
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Metabolism of pravastatin sodium in isolated rat hepatocytes. II. Structure elucidation of the metabolites by n.m.r. spectroscopy.
    Nakamura T; Yoda K; Kuwano H; Miyaguchi K; Muramatsu S; Takahagi H; Kinoshita T
    Xenobiotica; 1991 Mar; 21(3):277-93. PubMed ID: 1907419
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evaluation of Oatp and Mrp2 activities in hepatobiliary excretion using newly developed positron emission tomography tracer [11C]dehydropravastatin in rats.
    Shingaki T; Takashima T; Ijuin R; Zhang X; Onoue T; Katayama Y; Okauchi T; Hayashinaka E; Cui Y; Wada Y; Suzuki M; Maeda K; Kusuhara H; Sugiyama Y; Watanabe Y
    J Pharmacol Exp Ther; 2013 Oct; 347(1):193-202. PubMed ID: 23926287
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sulfation of hydroxylamines and hydroxamic acids in liver cytosol from male and female rats and purified aryl sulfotransferase IV.
    Gilissen RA; Ringer DP; Stavenuiter HJ; Mulder GJ; Meerman JH
    Carcinogenesis; 1992 Oct; 13(10):1699-703. PubMed ID: 1423828
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CYP109E1 is a novel versatile statin and terpene oxidase from Bacillus megaterium.
    Putkaradze N; Litzenburger M; Abdulmughni A; Milhim M; Brill E; Hannemann F; Bernhardt R
    Appl Microbiol Biotechnol; 2017 Dec; 101(23-24):8379-8393. PubMed ID: 29018905
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Syntheses of (+/-)-methyl 6'alpha-demethyl-6'alpha-cyanoabscisate and (+/-)-methyl 6'alpha-demethyl-6'alpha-methoxycarbonylabscisate.
    Inoue T; Oritani T
    Biosci Biotechnol Biochem; 2000 May; 64(5):1071-4. PubMed ID: 10879485
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis, and cytotoxicity of stabilized mycolactone analogs.
    Babu VS; Zhou Y; Kishi Y
    Bioorg Med Chem Lett; 2017 Mar; 27(5):1274-1277. PubMed ID: 28159417
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Substance-dependent sex differences in the activation of benzylic alcohols to mutagens by hepatic sulfotransferases of the rat.
    Glatt H; Pauly K; Frank H; Seidel A; Oesch F; Harvey RG; Werle-Schneider G
    Carcinogenesis; 1994 Nov; 15(11):2605-11. PubMed ID: 7955113
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Primary active transport of pravastatin across the liver canalicular membrane in normal and mutant Eisai hyperbilirubinemic rats.
    Yamazaki M; Kobayashi K; Sugiyama Y
    Biopharm Drug Dispos; 1996 Oct; 17(7):607-21. PubMed ID: 8894118
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Major inter-species differences in the rates of O-sulphonation and O-glucuronylation of alpha-hydroxytamoxifen in vitro: a metabolic disparity protecting human liver from the formation of tamoxifen-DNA adducts.
    Boocock DJ; Maggs JL; Brown K; White IN; Park BK
    Carcinogenesis; 2000 Oct; 21(10):1851-8. PubMed ID: 11023543
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hepatoselective carrier-mediated sodium-independent uptake of pravastatin and pravastatin-lactone.
    Ziegler K; Hummelsiep S
    Biochim Biophys Acta; 1993 Nov; 1153(1):23-33. PubMed ID: 8241247
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Bioactivation of 5-hydroxymethyl-2-furaldehyde to an electrophilic and mutagenic allylic sulfuric acid ester.
    Lee YC; Shlyankevich M; Jeong HK; Douglas JS; Surh YJ
    Biochem Biophys Res Commun; 1995 Apr; 209(3):996-1002. PubMed ID: 7733994
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sulfotransferase-mediated activation of 4-hydroxy- and 3,4-dihydroxy-3,4-dihydrocyclopenta[c,d]pyrene, major metabolites of cyclopenta[c,d]pyrene.
    Surh YJ; Kwon H; Tannenbaum SR
    Cancer Res; 1993 Mar; 53(5):1017-22. PubMed ID: 8439948
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.