1470 related articles for article (PubMed ID: 8484984)
1. EO9: a novel bioreductive alkylating indoloquinone with preferential solid tumour activity and lack of bone marrow toxicity in preclinical models.
Hendriks HR; Pizao PE; Berger DP; Kooistra KL; Bibby MC; Boven E; Dreef-van der Meulen HC; Henrar RE; Fiebig HH; Double JA
Eur J Cancer; 1993; 29A(6):897-906. PubMed ID: 8484984
[TBL] [Abstract][Full Text] [Related]
2. Unusually marked hypoxic sensitization to indoloquinone EO9 and mitomycin C in a human colon-tumour cell line that lacks DT-diaphorase activity.
Plumb JA; Workman P
Int J Cancer; 1994 Jan; 56(1):134-9. PubMed ID: 8262670
[TBL] [Abstract][Full Text] [Related]
3. DT-diaphorase activity correlates with sensitivity to the indoloquinone EO9 in mouse and human colon carcinomas.
Walton MI; Bibby MC; Double JA; Plumb JA; Workman P
Eur J Cancer; 1992; 28A(10):1597-600. PubMed ID: 1389472
[TBL] [Abstract][Full Text] [Related]
4. Clinical studies with EO9, a new indoloquinone bioreductive alkylating cytotoxic agent. EORTC Early Clinical Trials Group.
Verweij J; Aamdal S; Schellens J; Koier I; Lund B
Oncol Res; 1994; 6(10-11):519-23. PubMed ID: 7620220
[TBL] [Abstract][Full Text] [Related]
5. EO9: relationship between DT-diaphorase levels and response in vitro and in vivo.
Collard J; Matthew AM; Double JA; Bibby MC
Br J Cancer; 1995 Jun; 71(6):1199-203. PubMed ID: 7779711
[TBL] [Abstract][Full Text] [Related]
6. Phase I trial with weekly EO9, a novel bioreductive alkylating indoloquinone, by the EORTC Early Clinical Study Group (ECSG).
Aamdal S; Lund B; Koier I; Houten M; Wanders J; Verweij J
Cancer Chemother Pharmacol; 2000; 45(1):85-8. PubMed ID: 10647507
[TBL] [Abstract][Full Text] [Related]
7. Potentiation of EO9 anti-tumour activity by hydralazine.
Bibby MC; Sleigh NR; Loadman PM; Double JA
Eur J Cancer; 1993; 29A(7):1033-5. PubMed ID: 8499134
[TBL] [Abstract][Full Text] [Related]
8. DT-diaphorase protects cells from the hypoxic cytotoxicity of indoloquinone EO9.
Plumb JA; Gerritsen M; Workman P
Br J Cancer; 1994 Dec; 70(6):1136-43. PubMed ID: 7526885
[TBL] [Abstract][Full Text] [Related]
9. Development, pharmacology, role of DT-diaphorase and prospects of the indoloquinone EO9.
Smitskamp-Wilms E; Hendriks HR; Peters GJ
Gen Pharmacol; 1996 Apr; 27(3):421-9. PubMed ID: 8723519
[TBL] [Abstract][Full Text] [Related]
10. Induction of DT-diaphorase by 1,2-dithiole-3-thiones in human tumour and normal cells and effect on anti-tumour activity of bioreductive agents.
Doherty GP; Leith MK; Wang X; Curphey TJ; Begleiter A
Br J Cancer; 1998 Apr; 77(8):1241-52. PubMed ID: 9579829
[TBL] [Abstract][Full Text] [Related]
11. Pharmacological and biochemical determinants of the antitumour activity of the indoloquinone EO9.
Cummings J; Spanswick VJ; Gardiner J; Ritchie A; Smyth JF
Biochem Pharmacol; 1998 Feb; 55(3):253-60. PubMed ID: 9484790
[TBL] [Abstract][Full Text] [Related]
12. In vitro activity of the novel indoloquinone EO-9 and the influence of pH on cytotoxicity.
Phillips RM; Hulbert PB; Bibby MC; Sleigh NR; Double JA
Br J Cancer; 1992 Mar; 65(3):359-64. PubMed ID: 1558788
[TBL] [Abstract][Full Text] [Related]
13. Factors affecting sensitivity to EO9 in rodent and human tumour cells in vitro: DT-diaphorase activity and hypoxia.
Robertson N; Haigh A; Adams GE; Stratford IJ
Eur J Cancer; 1994; 30A(7):1013-9. PubMed ID: 7946565
[TBL] [Abstract][Full Text] [Related]
14. Phase I and pharmacologic study of the novel indoloquinone bioreductive alkylating cytotoxic drug E09.
Schellens JH; Planting AS; van Acker BA; Loos WJ; de Boer-Dennert M; van der Burg ME; Koier I; Krediet RT; Stoter G; Verweij J
J Natl Cancer Inst; 1994 Jun; 86(12):906-12. PubMed ID: 8196081
[TBL] [Abstract][Full Text] [Related]
15. Enhancement of interstitial photodynamic therapy by mitomycin C and EO9 in a mouse tumour model.
Baas P; Michielsen C; Oppelaar H; van Zandwijk N; Stewart FA
Int J Cancer; 1994 Mar; 56(6):880-5. PubMed ID: 8119776
[TBL] [Abstract][Full Text] [Related]
16. DT-diaphorase activity in normal and neoplastic human tissues; an indicator for sensitivity to bioreductive agents?
Smitskamp-Wilms E; Giaccone G; Pinedo HM; van der Laan BF; Peters GJ
Br J Cancer; 1995 Oct; 72(4):917-21. PubMed ID: 7547240
[TBL] [Abstract][Full Text] [Related]
17. EO9 phase II study in advanced breast, gastric, pancreatic and colorectal carcinoma by the EORTC Early Clinical Studies Group.
Dirix LY; Tonnesen F; Cassidy J; Epelbaum R; ten Bokkel Huinink WW; Pavlidis N; Sorio R; Gamucci T; Wolff I; Te Velde A; Lan J; Verweij J
Eur J Cancer; 1996 Oct; 32A(11):2019-22. PubMed ID: 8943690
[TBL] [Abstract][Full Text] [Related]
18. Chemosensitivity to the indoloquinone EO9 is correlated with DT-diaphorase activity and its gene expression.
Smitskamp-Wilms E; Peters GJ; Pinedo HM; van Ark-Otte J; Giaccone G
Biochem Pharmacol; 1994 Apr; 47(8):1325-32. PubMed ID: 7514407
[TBL] [Abstract][Full Text] [Related]
19. Reductase enzyme expression across the National Cancer Institute Tumor cell line panel: correlation with sensitivity to mitomycin C and EO9.
Fitzsimmons SA; Workman P; Grever M; Paull K; Camalier R; Lewis AD
J Natl Cancer Inst; 1996 Mar; 88(5):259-69. PubMed ID: 8614004
[TBL] [Abstract][Full Text] [Related]
20. Phase I pharmacokinetics and limited sampling strategies for the bioreductive alkylating drug EO9. EORTC Early Clinical Trials Group.
McLeod HL; Graham MA; Aamdal S; Setanoians A; Groot Y; Lund B
Eur J Cancer; 1996 Aug; 32A(9):1518-22. PubMed ID: 8911111
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
