BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 8487257)

  • 1. New indole derivatives as potent and selective serotonin uptake inhibitors.
    Malleron JL; Guérémy C; Mignani S; Peyronel JF; Truchon A; Blanchard JC; Doble A; Laduron P; Piot O; Zundel JL
    J Med Chem; 1993 Apr; 36(9):1194-202. PubMed ID: 8487257
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and pharmacological evaluation of new (indol-3-yl)alkylamides and alkylamines acting as potential serotonin uptake inhibitors.
    Fouchard F; Menciu C; Duflos M; Le Baut G; Lambrey B; Mourgues M; Perrissoud D
    Arzneimittelforschung; 1999 Feb; 49(2):96-105. PubMed ID: 10083976
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 5-HT reuptake inhibitors with 5-HT(1B/1D) antagonistic activity: a new approach toward efficient antidepressants.
    Matzen L; van Amsterdam C; Rautenberg W; Greiner HE; Harting J; Seyfried CA; Böttcher H
    J Med Chem; 2000 Mar; 43(6):1149-57. PubMed ID: 10737747
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Selective, centrally acting serotonin 5-HT2 antagonists. 2. Substituted 3-(4-fluorophenyl)-1H-indoles.
    Andersen K; Perregaard J; Arnt J; Nielsen JB; Begtrup M
    J Med Chem; 1992 Dec; 35(26):4823-31. PubMed ID: 1336054
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Selective, centrally acting serotonin 5-HT2 antagonists. 1. 2- and 6-substituted 1-phenyl-3-(4-piperidinyl)-1H-indoles.
    Perregaard J; Andersen K; Hyttel J; Sánchez C
    J Med Chem; 1992 Dec; 35(26):4813-22. PubMed ID: 1336053
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Serotonin 5-HT2 receptor, dopamine D2 receptor, and alpha 1 adrenoceptor antagonists. Conformationally flexible analogues of the atypical antipsychotic sertindole.
    Andersen K; Liljefors T; Hyttel J; Perregaard J
    J Med Chem; 1996 Sep; 39(19):3723-38. PubMed ID: 8809161
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and D2-like binding affinity of 4,5-dihydro-1H-benzo[g]indole-3-carboxamide derivatives as conformationally restricted 5-phenyl-pyrrole-3-carboxamide analogs.
    Pinna GA; Curzu MM; Sechi M; Chelucci G; Vianello P; Maciocco E
    Farmaco; 1998; 53(10-11):684-9. PubMed ID: 10205854
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dual 5-HT1A agonists and 5-HT re-uptake inhibitors by combination of indole-butyl-amine and chromenonyl-piperazine structural elements in a single molecular entity.
    Heinrich T; Böttcher H; Schiemann K; Hölzemann G; Schwarz M; Bartoszyk GD; van Amsterdam C; Greiner HE; Seyfried CA
    Bioorg Med Chem; 2004 Sep; 12(18):4843-52. PubMed ID: 15336263
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Peripheral and spinal 5-HT receptors participate in the pronociceptive and antinociceptive effects of fluoxetine in rats.
    Cervantes-Durán C; Rocha-González HI; Granados-Soto V
    Neuroscience; 2013 Nov; 252():396-409. PubMed ID: 23994595
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Further studies on conformationally constrained tricyclic tropane analogues and their uptake inhibition at monoamine transporter sites: synthesis of (Z)-9-(substituted arylmethylene)-7-azatricyclo[4.3.1.0(3,7)]decanes as a novel class of serotonin transporter inhibitors.
    Zhang A; Zhou G; Hoepping A; Mukhopadhyaya J; Johnson KM; Zhang M; Kozikowski AP
    J Med Chem; 2002 Apr; 45(9):1930-41. PubMed ID: 11960503
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lu 35-138 ((+)-(S)-3-{1-[2-(1-acetyl-2,3-dihydro-1H-indol-3-yl)ethyl]-3,6-dihydro-2H-pyridin-4-yl}-6-chloro-1H-indole), a dopamine D4 receptor antagonist and serotonin reuptake inhibitor: characterisation of its in vitro profile and pre-clinical antipsychotic potential.
    Hertel P; Didriksen M; Pouzet B; Brennum LT; Søby KK; Larsen AK; Christoffersen CT; Ramirez T; Marcus MM; Svensson TH; Di Matteo V; Esposito E; Bang-Andersen B; Arnt J
    Eur J Pharmacol; 2007 Nov; 573(1-3):148-60. PubMed ID: 17689529
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, structure-activity relationships, and biological properties of 1-heteroaryl-4-[omega-(1H-indol-3-yl)alkyl]piperazines, novel potential antipsychotics combining potent dopamine D2 receptor antagonism with potent serotonin reuptake inhibition.
    Smid P; Coolen HK; Keizer HG; van Hes R; de Moes JP; den Hartog AP; Stork B; Plekkenpol RH; Niemann LC; Stroomer CN; Tulp MT; van Stuivenberg HH; McCreary AC; Hesselink MB; Herremans AH; Kruse CG
    J Med Chem; 2005 Nov; 48(22):6855-69. PubMed ID: 16250644
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Conformationally restricted homotryptamines. 2. Indole cyclopropylmethylamines as selective serotonin reuptake inhibitors.
    Mattson RJ; Catt JD; Denhart DJ; Deskus JA; Ditta JL; Higgins MA; Marcin LR; Sloan CP; Beno BR; Gao Q; Cunningham MA; Mattson GK; Molski TF; Taber MT; Lodge NJ
    J Med Chem; 2005 Sep; 48(19):6023-34. PubMed ID: 16162005
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological screening of novel indolalkyl arenes targeting the serotonine transporter.
    Ojeda-Gómez C; Pessoa-Mahana H; Iturriaga-Vásquez P; Pessoa-Mahana CD; Recabarren-Gajardo G; Méndez-Rojas C
    Arch Pharm (Weinheim); 2014 Mar; 347(3):174-84. PubMed ID: 24339227
    [TBL] [Abstract][Full Text] [Related]  

  • 15. LY367265, an inhibitor of the 5-hydroxytryptamine transporter and 5-hydroxytryptamine(2A) receptor antagonist: a comparison with the antidepressant, nefazodone.
    Pullar IA; Carney SL; Colvin EM; Lucaites VL; Nelson DL; Wedley S
    Eur J Pharmacol; 2000 Oct; 407(1-2):39-46. PubMed ID: 11050288
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Syntheses and binding studies of new [(aryl)(aryloxy)methyl]piperidine derivatives and related compounds as potential antidepressant drugs with high affinity for serotonin (5-HT) and norepinephrine (NE) transporters.
    Orjales A; Mosquera R; Toledo A; Pumar MC; García N; Cortizo L; Labeaga L; Innerárity A
    J Med Chem; 2003 Dec; 46(25):5512-32. PubMed ID: 14640559
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and transporter binding properties of bridged piperazine analogues of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909).
    Zhang Y; Rothman RB; Dersch CM; de Costa BR; Jacobson AE; Rice KC
    J Med Chem; 2000 Dec; 43(25):4840-9. PubMed ID: 11123994
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and biological evaluation of new multi-target 3-(1H-indol-3-yl)pyrrolidine-2,5-dione derivatives with potential antidepressant effect.
    Wróbel MZ; Chodkowski A; Herold F; Marciniak M; Dawidowski M; Siwek A; Starowicz G; Stachowicz K; Szewczyk B; Nowak G; Belka M; Bączek T; Satała G; Bojarski AJ; Turło J
    Eur J Med Chem; 2019 Dec; 183():111736. PubMed ID: 31586817
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Conformationally restricted homotryptamines 3. Indole tetrahydropyridines and cyclohexenylamines as selective serotonin reuptake inhibitors.
    Deskus JA; Epperson JR; Sloan CP; Cipollina JA; Dextraze P; Qian-Cutrone J; Gao Q; Ma B; Beno BR; Mattson GK; Molski TF; Krause RG; Taber MT; Lodge NJ; Mattson RJ
    Bioorg Med Chem Lett; 2007 Jun; 17(11):3099-104. PubMed ID: 17391962
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sigma ligands with subnanomolar affinity and preference for the sigma 2 binding site. 1. 3-(omega-aminoalkyl)-1H-indoles.
    Perregaard J; Moltzen EK; Meier E; Sánchez C
    J Med Chem; 1995 May; 38(11):1998-2008. PubMed ID: 7783131
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.