These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 8494902)

  • 1. Binding of guanosine and 3' splice site analogues to a group I ribozyme: interactions with functional groups of guanosine and with additional nucleotides.
    Moran S; Kierzek R; Turner DH
    Biochemistry; 1993 May; 32(19):5247-56. PubMed ID: 8494902
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Probing the role of a secondary structure element at the 5'- and 3'-splice sites in group I intron self-splicing: the tetrahymena L-16 ScaI ribozyme reveals a new role of the G.U pair in self-splicing.
    Karbstein K; Lee J; Herschlag D
    Biochemistry; 2007 Apr; 46(16):4861-75. PubMed ID: 17385892
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Exocyclic amine of the conserved G.U pair at the cleavage site of the Tetrahymena ribozyme contributes to 5'-splice site selection and transition state stabilization.
    Strobel SA; Cech TR
    Biochemistry; 1996 Jan; 35(4):1201-11. PubMed ID: 8573575
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A positive entropy change for guanosine binding and for the chemical step in the Tetrahymena ribozyme reaction.
    McConnell TS; Cech TR
    Biochemistry; 1995 Mar; 34(12):4056-67. PubMed ID: 7696271
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Guanosine binding to the Tetrahymena ribozyme: thermodynamic coupling with oligonucleotide binding.
    McConnell TS; Cech TR; Herschlag D
    Proc Natl Acad Sci U S A; 1993 Sep; 90(18):8362-6. PubMed ID: 8378306
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mutations at the guanosine-binding site of the Tetrahymena ribozyme also affect site-specific hydrolysis.
    Legault P; Herschlag D; Celander DW; Cech TR
    Nucleic Acids Res; 1992 Dec; 20(24):6613-9. PubMed ID: 1480482
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Comparison of binding of mixed ribose-deoxyribose analogues of CUCU to a ribozyme and to GGAGAA by equilibrium dialysis: evidence for ribozyme specific interactions with 2' OH groups.
    Bevilacqua PC; Turner DH
    Biochemistry; 1991 Nov; 30(44):10632-40. PubMed ID: 1931984
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 1. Kinetic description of the reaction of an RNA substrate complementary to the active site.
    Herschlag D; Cech TR
    Biochemistry; 1990 Nov; 29(44):10159-71. PubMed ID: 2271645
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Contributions of 2'-hydroxyl groups of the RNA substrate to binding and catalysis by the Tetrahymena ribozyme. An energetic picture of an active site composed of RNA.
    Herschlag D; Eckstein F; Cech TR
    Biochemistry; 1993 Aug; 32(32):8299-311. PubMed ID: 7688572
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanistic investigations of a ribozyme derived from the Tetrahymena group I intron: insights into catalysis and the second step of self-splicing.
    Mei R; Herschlag D
    Biochemistry; 1996 May; 35(18):5796-809. PubMed ID: 8639540
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tertiary interactions with the internal guide sequence mediate docking of the P1 helix into the catalytic core of the Tetrahymena ribozyme.
    Strobel SA; Cech TR
    Biochemistry; 1993 Dec; 32(49):13593-604. PubMed ID: 7504953
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A kinetic and thermodynamic framework for the Azoarcus group I ribozyme reaction.
    Gleitsman KR; Herschlag DH
    RNA; 2014 Nov; 20(11):1732-46. PubMed ID: 25246656
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Guanosine binding required for cyclization of the self-splicing intervening sequence ribonucleic acid from Tetrahymena thermophila.
    Tanner NK; Cech TR
    Biochemistry; 1987 Jun; 26(12):3330-40. PubMed ID: 2443161
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The importance of being ribose at the cleavage site in the Tetrahymena ribozyme reaction.
    Herschlag D; Eckstein F; Cech TR
    Biochemistry; 1993 Aug; 32(32):8312-21. PubMed ID: 7688573
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A Pneumocystis carinii group I intron ribozyme that does not require 2' OH groups on its 5' exon mimic for binding to the catalytic core.
    Testa SM; Haidaris CG; Gigliotti F; Turner DH
    Biochemistry; 1997 Dec; 36(49):15303-14. PubMed ID: 9398259
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Guanosine binds to the Tetrahymena ribozyme in more than one step, and its 2'-OH and the nonbridging pro-Sp phosphoryl oxygen at the cleavage site are required for productive docking.
    Profenno LA; Kierzek R; Testa SM; Turner DH
    Biochemistry; 1997 Oct; 36(41):12477-85. PubMed ID: 9376352
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Fluorescence-detected stopped flow with a pyrene labeled substrate reveals that guanosine facilitates docking of the 5' cleavage site into a high free energy binding mode in the Tetrahymena ribozyme.
    Bevilacqua PC; Li Y; Turner DH
    Biochemistry; 1994 Sep; 33(37):11340-8. PubMed ID: 7727385
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A preorganized active site in the crystal structure of the Tetrahymena ribozyme.
    Golden BL; Gooding AR; Podell ER; Cech TR
    Science; 1998 Oct; 282(5387):259-64. PubMed ID: 9841391
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dissection of the role of the conserved G.U pair in group I RNA self-splicing.
    Knitt DS; Narlikar GJ; Herschlag D
    Biochemistry; 1994 Nov; 33(46):13864-79. PubMed ID: 7947795
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Replacement of the conserved G.U with a G-C pair at the cleavage site of the Tetrahymena ribozyme decreases binding, reactivity, and fidelity.
    Pyle AM; Moran S; Strobel SA; Chapman T; Turner DH; Cech TR
    Biochemistry; 1994 Nov; 33(46):13856-63. PubMed ID: 7947794
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.