These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

152 related articles for article (PubMed ID: 8496916)

  • 1. Synthesis and biological activity of spirocyclic benzopyran imidazolone potassium channel openers.
    Gadwood RC; Kamdar BV; Dubray LA; Wolfe ML; Smith MP; Watt W; Mizsak SA; Groppi VE
    J Med Chem; 1993 May; 36(10):1480-7. PubMed ID: 8496916
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis, and pharmacological evaluation of R/S-3,4-dihydro-2,2-dimethyl- 6-halo-4-(phenylaminocarbonylamino)-2H-1-benzopyrans: toward tissue-selective pancreatic beta-cell KATP channel openers structurally related to (+/-)-cromakalim.
    Sebille S; Gall D; de Tullio P; Florence X; Lebrun P; Pirotte B
    J Med Chem; 2006 Jul; 49(15):4690-7. PubMed ID: 16854075
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New R/S-3,4-dihydro-2,2-dimethyl-2H-1-benzopyrans as K(ATP) channel openers: modulation of the 4-position.
    Florence X; Sebille S; Tullio Pd; Lebrun P; Pirotte B
    Bioorg Med Chem; 2009 Nov; 17(22):7723-31. PubMed ID: 19822435
    [TBL] [Abstract][Full Text] [Related]  

  • 4. New R/S-3,4-dihydro-2,2-dimethyl-6-halo-4-(phenylaminothiocarbonylamino)-2H-1-benzopyrans structurally related to (+/-)-cromakalim as tissue-selective pancreatic beta-cell K(ATP) channel openers.
    Sebille S; de Tullio P; Florence X; Becker B; Antoine MH; Michaux C; Wouters J; Pirotte B; Lebrun P
    Bioorg Med Chem; 2008 May; 16(10):5704-19. PubMed ID: 18406154
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Potassium channel activators based on the benzopyran substructure: synthesis and activity of the C-8 substituent.
    Thompson R; Doggrell S; Hoberg JO
    Bioorg Med Chem; 2003 Apr; 11(8):1663-8. PubMed ID: 12659752
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Relaxant activity of 4-amido-3,4-dihydro-2H-1-benzopyran-3-ols and 4-amido-2H-1-benzopyrans on guinea pig isolated trachealis.
    Buckle DR; Arch JR; Fenwick AE; Houge-Frydrych CS; Pinto IL; Smith DG; Taylor SG; Tedder JM
    J Med Chem; 1990 Nov; 33(11):3028-34. PubMed ID: 2231602
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation by cromakalim of pre- and post-synaptic ATP-sensitive K+ channels in substantia nigra.
    Häusser MA; de Weille JR; Lazdunski M
    Biochem Biophys Res Commun; 1991 Jan; 174(2):909-14. PubMed ID: 1899575
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Potassium channel modulation: a new drug principle for regulation of smooth muscle contractility. Studies on isolated airways and arteries.
    Nielsen-Kudsk JE
    Dan Med Bull; 1996 Dec; 43(5):429-47. PubMed ID: 8960816
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differential effects of endothelin-1 on the vasorelaxant properties of benzopyran and non-benzopyran potassium channel openers.
    Lawson K; Barras M; Zazzi-Sudriez E; Martin DJ; Armstrong JM; Hicks PE
    Br J Pharmacol; 1992 Sep; 107(1):58-65. PubMed ID: 1422579
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Relaxant activity of 6-cyano-2,2-dimethyl-2H-1-benzopyran-4-carboxamides and -thiocarboxamides and their analogues in guinea pig trachealis.
    Arch JR; Buckle DR; Carey C; Parr-Dobrzanski H; Faller A; Foster KA; Houge-Frydrych CS; Pinto IL; Smith DG; Taylor SG
    J Med Chem; 1991 Aug; 34(8):2588-94. PubMed ID: 1875351
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The individual enantiomers of cis-cromakalim possess K+ channel opening activity.
    Quast U; Villhauer EB
    Eur J Pharmacol; 1993 Apr; 245(2):165-71. PubMed ID: 8491256
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and aldose reductase inhibitory activity of 2-substituted 6-fluoro-2,3-dihydrospiro[4H-1-benzopyran-4,4'-imidazolidine]-2',5'-dio nes.
    Unno R; Yamaguchi T; Usui T; Kakigami T; Fukushima M; Mizuno K; Baba Y; Kurono M
    Chem Pharm Bull (Tokyo); 1994 Jul; 42(7):1474-8. PubMed ID: 7923471
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Spirocyclic benzopyran-based derivatives as new anti-ischemic activators of mitochondrial ATP-sensitive potassium channel.
    Breschi MC; Calderone V; Digiacomo M; Manganaro M; Martelli A; Minutolo F; Rapposelli S; Testai L; Tonelli F; Balsamo A
    J Med Chem; 2008 Nov; 51(21):6945-54. PubMed ID: 18925735
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and antihypertensive activity of 4-(diazabicyclo[4.1.0]-heptenyloxy)benzopyran derivatives and their analogues.
    Horino H; Mimura T; Kagechika K; Ohta M; Kubo H; Kitagawa M
    Chem Pharm Bull (Tokyo); 1998 Apr; 46(4):602-9. PubMed ID: 9579035
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evidence that acetylcholine-mediated hyperpolarization of the rat small mesenteric artery does not involve the K+ channel opened by cromakalim.
    McPherson GA; Angus JA
    Br J Pharmacol; 1991 May; 103(1):1184-90. PubMed ID: 1908733
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cardioselective antiischemic ATP-sensitive potassium channel openers. 2. Structure-activity studies on benzopyranylcyanoguanidines: modification of the benzopyran ring.
    Atwal KS; Grover GJ; Ferrara FN; Ahmed SZ; Sleph PG; Dzwonczyk S; Normandin DE
    J Med Chem; 1995 May; 38(11):1966-73. PubMed ID: 7783128
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effects of K+ channel agonists cromakalim and pinacidil on rat basilar artery smooth muscle cells are mediated by Ca(++)-activated K+ channels.
    Stockbridge N; Zhang H; Weir B
    Biochem Biophys Res Commun; 1991 Nov; 181(1):172-8. PubMed ID: 1958186
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comparative effects of the potassium channel openers cromakalim and pinacidil and the cromakalim analog U-89232 on isolated vascular and cardiac tissue.
    Norman NR; Toombs CF; Khan SA; Buchanan LV; Cimini MG; Gibson JK; Meisheri KD; Shebuski RJ
    Pharmacology; 1994 Aug; 49(2):86-95. PubMed ID: 7972325
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In vitro and in vivo comparison of two K+ channel openers, diazoxide and cromakalim, and their inhibition by glibenclamide.
    Quast U; Cook NS
    J Pharmacol Exp Ther; 1989 Jul; 250(1):261-71. PubMed ID: 2501478
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacology and structure-activity relationships for KATP modulators: tissue-selective KATP openers.
    Atwal KS
    J Cardiovasc Pharmacol; 1994; 24 Suppl 4():S12-7. PubMed ID: 7898103
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.