These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 8504082)

  • 1. Effect of mutations of ionic amino acids of cytochrome P450 1A2 on catalytic activities toward 7-ethoxycoumarin and methanol.
    Mayuzumi H; Sambongi C; Hiroya K; Shimizu T; Tateishi T; Hatano M
    Biochemistry; 1993 Jun; 32(21):5622-8. PubMed ID: 8504082
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential roles of Glu318 and Thr319 in cytochrome P450 1A2 catalysis supported by NADPH-cytochrome P450 reductase and tert-butyl hydroperoxide.
    Hiroya K; Murakami Y; Shimizu T; Hatano M; Ortiz de Montellano PR
    Arch Biochem Biophys; 1994 May; 310(2):397-401. PubMed ID: 7910007
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Requirements for cytochrome b5 in the oxidation of 7-ethoxycoumarin, chlorzoxazone, aniline, and N-nitrosodimethylamine by recombinant cytochrome P450 2E1 and by human liver microsomes.
    Yamazaki H; Nakano M; Gillam EM; Bell LC; Guengerich FP; Shimada T
    Biochem Pharmacol; 1996 Jul; 52(2):301-9. PubMed ID: 8694855
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Essential role of His163 of cytochrome P450 1A2 in catalytic functions associated with cytochrome b5.
    Mayuzumi H; Shimizu T; Sambongi C; Hiroya K; Hatano M
    Arch Biochem Biophys; 1994 May; 310(2):367-72. PubMed ID: 8179321
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 7-Ethoxycoumarin O-deethylation catalyzed by cytochromes P450 1A2 and 2E1 in human liver microsomes.
    Yamazaki H; Inoue K; Mimura M; Oda Y; Guengerich FP; Shimada T
    Biochem Pharmacol; 1996 Feb; 51(3):313-9. PubMed ID: 8573198
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Site-directed mutageneses of rat liver cytochrome P-450d: catalytic activities toward benzphetamine and 7-ethoxycoumarin.
    Furuya H; Shimizu T; Hirano K; Hatano M; Fujii-Kuriyama Y; Raag R; Poulos TL
    Biochemistry; 1989 Aug; 28(17):6848-57. PubMed ID: 2819037
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Influence of ionic strength on the P450 monooxygenase reaction and role of cytochrome b5 in the process.
    Schenkman JB; Voznesensky AI; Jansson I
    Arch Biochem Biophys; 1994 Oct; 314(1):234-41. PubMed ID: 7944401
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Recombinant human cytochrome P450 1A2 and an N-terminal-truncated form: construction, purification, aggregation properties, and interactions with flavodoxin, ferredoxin, and NADPH-cytochrome P450 reductase.
    Dong MS; Yamazaki H; Guo Z; Guengerich FP
    Arch Biochem Biophys; 1996 Mar; 327(1):11-9. PubMed ID: 8615680
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Role of Glu318 and Thr319 in the catalytic function of cytochrome P450d (P4501A2): effects of mutations on the methanol hydroxylation.
    Hiroya K; Ishigooka M; Shimizu T; Hatano M
    FASEB J; 1992 Jan; 6(2):749-51. PubMed ID: 1347023
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Probing the role of lysines and arginines in the catalytic function of cytochrome P450d by site-directed mutagenesis. Interaction with NADPH-cytochrome P450 reductase.
    Shimizu T; Tateishi T; Hatano M; Fujii-Kuriyama Y
    J Biol Chem; 1991 Feb; 266(6):3372-5. PubMed ID: 1899862
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Engineering bacterial cytochrome P450 (P450) BM3 into a prototype with human P450 enzyme activity using indigo formation.
    Park SH; Kim DH; Kim D; Kim DH; Jung HC; Pan JG; Ahn T; Kim D; Yun CH
    Drug Metab Dispos; 2010 May; 38(5):732-9. PubMed ID: 20100815
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effect of mutations at Lys250, Arg251, and Lys253 of cytochrome P450 1A2 on the catalytic activities and the bindings of bifunctional axial ligands.
    Krainev AG; Shimizu T; Hiroya K; Hatano M
    Arch Biochem Biophys; 1992 Oct; 298(1):198-203. PubMed ID: 1524428
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Electrostatic interaction between cytochrome P450 and NADPH-P450 reductase: comparison of mixed and fused systems consisting of rat cytochrome P450 1A1 and yeast NADPH-P450 reductase.
    Kondo S; Sakaki T; Ohkawa H; Inouye K
    Biochem Biophys Res Commun; 1999 Apr; 257(2):273-8. PubMed ID: 10198202
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Chiral recognition at cytochrome P450 1A2 active site: effects of mutations at the putative distal site on the bindings of asymmetrical axial ligands.
    Krainev AG; Shimizu T; Ishigooka M; Hiroya K; Hatano M
    Biochemistry; 1993 Mar; 32(8):1951-7. PubMed ID: 8448154
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chemical modification of microsomal cytochrome P450: role of lysyl residues in hydroxylation activity.
    Kunz BC; Richter C
    FEBS Lett; 1983 Sep; 161(2):311-4. PubMed ID: 6413255
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A genetically engineered P450 monooxygenase: construction of the functional fused enzyme between rat cytochrome P450c and NADPH-cytochrome P450 reductase.
    Murakami H; Yabusaki Y; Sakaki T; Shibata M; Ohkawa H
    DNA; 1987 Jun; 6(3):189-97. PubMed ID: 3109864
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Coexpression of genetically engineered fused enzyme between yeast NADPH-P450 reductase and human cytochrome P450 3A4 and human cytochrome b5 in yeast.
    Hayashi K; Sakaki T; Kominami S; Inouye K; Yabusaki Y
    Arch Biochem Biophys; 2000 Sep; 381(1):164-70. PubMed ID: 11019832
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of acidic residues in the interaction of NADPH-cytochrome P450 oxidoreductase with cytochrome P450 and cytochrome c.
    Shen AL; Kasper CB
    J Biol Chem; 1995 Nov; 270(46):27475-80. PubMed ID: 7499204
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The effects of cytochrome b5, NADPH-P450 reductase, and lipid on the rate of 6 beta-hydroxylation of testosterone as catalyzed by a human P450 3A4 fusion protein.
    Shet MS; Faulkner KM; Holmans PL; Fisher CW; Estabrook RW
    Arch Biochem Biophys; 1995 Apr; 318(2):314-21. PubMed ID: 7733659
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes.
    Yamazaki H; Guo Z; Persmark M; Mimura M; Inoue K; Guengerich FP; Shimada T
    Mol Pharmacol; 1994 Sep; 46(3):568-77. PubMed ID: 7935340
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.