These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 8506276)

  • 1. Transmembrane signaling by an insulin receptor lacking a cytoplasmic beta-subunit domain.
    Sasaoka T; Takata Y; Kusari J; Anderson CM; Langlois WJ; Olefsky JM
    Proc Natl Acad Sci U S A; 1993 May; 90(10):4379-83. PubMed ID: 8506276
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanisms of enhanced transmembrane signaling by an insulin receptor lacking a cytoplasmic beta-subunit domain.
    Sasaoka T; Langlois WJ; Rose DW; Olefsky JM
    J Biol Chem; 1995 May; 270(18):10885-92. PubMed ID: 7738028
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Insulin internalization in the absence of the insulin receptor tyrosine kinase domain is insufficient for mediating intracellular biological effects.
    Schranz DB; Rohilla AM; Anderson C; Wood WM; Berhanu P
    Biochem Biophys Res Commun; 1996 Oct; 227(2):600-7. PubMed ID: 8878559
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A domain of the insulin receptor required for endocytosis in rat fibroblasts.
    Thies RS; Webster NJ; McClain DA
    J Biol Chem; 1990 Jun; 265(17):10132-7. PubMed ID: 2161833
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Deletion of exon 21 of the insulin receptor eliminates tyrosine kinase activity but preserves mitogenic signaling.
    Rolband GC; Williams JF; Webster NJ; Hsu D; Olefsky JM
    Biochemistry; 1993 Dec; 32(49):13545-50. PubMed ID: 8257690
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mechanisms of receptor-mediated transmembrane communication.
    Ellis L; Morgan DO; Clauser E; Edery M; Jong SM; Wang LH; Roth RA; Rutter WJ
    Cold Spring Harb Symp Quant Biol; 1986; 51 Pt 2():773-84. PubMed ID: 3472760
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Enhanced insulin-induced mitogenesis and mitogen-activated protein kinase activities in mutant insulin receptors with substitution of two COOH-terminal tyrosine autophosphorylation sites by phenylalanine.
    Ando A; Momomura K; Tobe K; Yamamoto-Honda R; Sakura H; Tamori Y; Kaburagi Y; Koshio O; Akanuma Y; Yazaki Y
    J Biol Chem; 1992 Jun; 267(18):12788-96. PubMed ID: 1618780
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Functional characterization of hybrid receptors composed of a truncated insulin receptor and wild type insulin-like growth factor 1 or insulin receptors.
    Langlois WJ; Sasaoka T; Yip CC; Olefsky JM
    Endocrinology; 1995 May; 136(5):1978-86. PubMed ID: 7720646
    [TBL] [Abstract][Full Text] [Related]  

  • 9. C-terminus or juxtamembrane deletions in the insulin receptor do not affect the glucose-dependent inhibition of the tyrosine kinase activity.
    Mosthaf L; Berti L; Kellerer M; Mushack J; Seffer E; Bossenmaier B; Coghlan M; Siddle K; Ullrich A; Häring HU
    Eur J Biochem; 1995 Feb; 227(3):787-91. PubMed ID: 7867639
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Normal insulin receptor substrate-1 phosphorylation in autophosphorylation-defective truncated insulin receptor. Evidence that phosphorylation of substrates might be sufficient for certain biological effects evoked by insulin.
    Yamamoto-Honda R; Kadowaki T; Momomura K; Tobe K; Tamori Y; Shibasaki Y; Mori Y; Kaburagi Y; Koshio O; Akanuma Y
    J Biol Chem; 1993 Aug; 268(22):16859-65. PubMed ID: 8344965
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Properties of a human insulin receptor with a COOH-terminal truncation. I. Insulin binding, autophosphorylation, and endocytosis.
    McClain DA; Maegawa H; Levy J; Huecksteadt T; Dull TJ; Lee J; Ullrich A; Olefsky JM
    J Biol Chem; 1988 Jun; 263(18):8904-11. PubMed ID: 2837467
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Properties of a human insulin receptor with a COOH-terminal truncation. II. Truncated receptors have normal kinase activity but are defective in signaling metabolic effects.
    Maegawa H; McClain DA; Freidenberg G; Olefsky JM; Napier M; Lipari T; Dull TJ; Lee J; Ullrich A
    J Biol Chem; 1988 Jun; 263(18):8912-7. PubMed ID: 2837468
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phorbol ester-mediated protein kinase C interaction with wild-type and COOH-terminal truncated insulin receptors.
    Anderson CM; Olefsky JM
    J Biol Chem; 1991 Nov; 266(32):21760-4. PubMed ID: 1657981
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Monoclonal antibodies mimic insulin activation of ribosomal protein S6 kinase without activation of insulin receptor tyrosine kinase. Studies in cells transfected with normal and mutant human insulin receptors.
    Sung CK; Maddux BA; Hawley DM; Goldfine ID
    J Biol Chem; 1989 Nov; 264(32):18951-9. PubMed ID: 2553727
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Augmented mitogenesis and impaired metabolic signaling mediated by a truncated insulin receptor.
    Thies RS; Ullrich A; McClain DA
    J Biol Chem; 1989 Aug; 264(22):12820-5. PubMed ID: 2753889
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human insulin receptors expressed in insulin-insensitive mouse fibroblasts couple with extant cellular effector systems to confer insulin sensitivity and responsiveness.
    Hofmann C; White MF; Whittaker J
    Endocrinology; 1989 Jan; 124(1):257-64. PubMed ID: 2462489
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Insulin signal transduction by a mutant human insulin receptor lacking the NPEY sequence. Evidence for an alternate mitogenic signaling pathway that is independent of Shc phosphorylation.
    Berhanu P; Anderson C; Hickman M; Ciaraldi TP
    J Biol Chem; 1997 Sep; 272(36):22884-90. PubMed ID: 9278451
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of glucose transport and c-fos and egr-1 expression in cells with mutated or endogenous growth hormone receptors.
    Gong TW; Meyer DJ; Liao J; Hodge CL; Campbell GS; Wang X; Billestrup N; Carter-Su C; Schwartz J
    Endocrinology; 1998 Apr; 139(4):1863-71. PubMed ID: 9528972
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transmembrane domain interactions are necessary for negative cooperativity of the insulin receptor.
    Whittaker J; Garcia P; Yu GQ; Mynarcik DC
    Mol Endocrinol; 1994 Nov; 8(11):1521-7. PubMed ID: 7877620
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Deletion of the insulin receptor beta-subunit acidic domain results in enhanced metabolic signaling.
    Rolband GC; Williams JF; Webster NJ; Olefsky JM
    Endocrinology; 1993 Sep; 133(3):1437-43. PubMed ID: 8396020
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.