These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

115 related articles for article (PubMed ID: 8506382)

  • 1. Prodrug activation via catalytic antibodies.
    Miyashita H; Karaki Y; Kikuchi M; Fujii I
    Proc Natl Acad Sci U S A; 1993 Jun; 90(11):5337-40. PubMed ID: 8506382
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Thermodynamic and structural basis for transition-state stabilization in antibody-catalyzed hydrolysis.
    Oda M; Ito N; Tsumuraya T; Suzuki K; Sakakura M; Fujii I
    J Mol Biol; 2007 May; 369(1):198-209. PubMed ID: 17428500
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A structural basis for transition-state stabilization in antibody-catalyzed hydrolysis: crystal structures of an abzyme at 1. 8 A resolution.
    Kristensen O; Vassylyev DG; Tanaka F; Morikawa K; Fujii I
    J Mol Biol; 1998 Aug; 281(3):501-11. PubMed ID: 9698565
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Selective chemotherapeutic strategies using catalytic antibodies: a common pro-moiety for antibody-directed abzyme prodrug therapy.
    Kakinuma H; Fujii I; Nishi Y
    J Immunol Methods; 2002 Nov; 269(1-2):269-81. PubMed ID: 12379367
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effects of substrate conformational strain on binding kinetics of catalytic antibodies.
    Oda M; Tsumuraya T; Fujii I
    Biophys Physicobiol; 2016; 13():135-138. PubMed ID: 27924267
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [Catalytic antibodies: generation of a new class of protein catalysts exploiting the immune system].
    Fujii I
    Yakugaku Zasshi; 1996 Aug; 116(8):606-21. PubMed ID: 8831262
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural basis of the transition-state stabilization in antibody-catalyzed hydrolysis.
    Sakakura M; Takahashi H; Shimba N; Fujii I; Shimada I
    J Mol Biol; 2007 Mar; 367(1):133-47. PubMed ID: 17239396
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Site-directed mutagenesis of active site contact residues in a hydrolytic abzyme: evidence for an essential histidine involved in transition state stabilization.
    Miyashita H; Hara T; Tanimura R; Fukuyama S; Cagnon C; Kohara A; Fujii I
    J Mol Biol; 1997 Apr; 267(5):1247-57. PubMed ID: 9150409
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In vivo activity in a catalytic antibody-prodrug system: Antibody catalyzed etoposide prodrug activation for selective chemotherapy.
    Shabat D; Lode HN; Pertl U; Reisfeld RA; Rader C; Lerner RA; Barbas CF
    Proc Natl Acad Sci U S A; 2001 Jun; 98(13):7528-33. PubMed ID: 11404472
    [TBL] [Abstract][Full Text] [Related]  

  • 10. [Catalytic antibody and its medical applications].
    Fujii I; Iwabuchi Y
    Nihon Rinsho; 1995 Feb; 53(2):518-27. PubMed ID: 7699882
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Simple method for selecting catalytic monoclonal antibodies that exhibit turnover and specificity.
    Tawfik DS; Zemel RR; Arad-Yellin R; Green BS; Eshhar Z
    Biochemistry; 1990 Oct; 29(42):9916-21. PubMed ID: 2271630
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Toward antibody-directed "abzyme" prodrug therapy, ADAPT: carbamate prodrug activation by a catalytic antibody and its in vitro application to human tumor cell killing.
    Wentworth P; Datta A; Blakey D; Boyle T; Partridge LJ; Blackburn GM
    Proc Natl Acad Sci U S A; 1996 Jan; 93(2):799-803. PubMed ID: 8570638
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Selective activation of anticancer prodrugs by monoclonal antibody-enzyme conjugates.
    Wallace PM; Senter PD
    Methods Find Exp Clin Pharmacol; 1994 Sep; 16(7):505-12. PubMed ID: 7885077
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antibacterial application of engineered bacteriophage nanomedicines: antibody-targeted, chloramphenicol prodrug loaded bacteriophages for inhibiting the growth of Staphylococcus aureus bacteria.
    Vaks L; Benhar I
    Methods Mol Biol; 2011; 726():187-206. PubMed ID: 21424451
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Display of a functional hetero-oligomeric catalytic antibody on the yeast cell surface.
    Lin Y; Tsumuraya T; Wakabayashi T; Shiraga S; Fujii I; Kondo A; Ueda M
    Appl Microbiol Biotechnol; 2003 Aug; 62(2-3):226-32. PubMed ID: 12883868
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Directed evolution governed by controlling the molecular recognition between an abzyme and its haptenic transition-state analog.
    Takahashi-Ando N; Kakinuma H; Fujii I; Nishi Y
    J Immunol Methods; 2004 Nov; 294(1-2):1-14. PubMed ID: 15604011
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A humanized immunoenzyme with enhanced activity for glucuronide prodrug activation in the tumor microenvironment.
    Chen KC; Wu SY; Leu YL; Prijovich ZM; Chen BM; Wang HE; Cheng TL; Roffler SR
    Bioconjug Chem; 2011 May; 22(5):938-48. PubMed ID: 21443266
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Prodrugs of anthracyclines for use in antibody-directed enzyme prodrug therapy.
    Florent JC; Dong X; Gaudel G; Mitaku S; Monneret C; Gesson JP; Jacquesy JC; Mondon M; Renoux B; Andrianomenjanahary S; Michel S; Koch M; Tillequin F; Gerken M; Czech J; Straub R; Bosslet K
    J Med Chem; 1998 Sep; 41(19):3572-81. PubMed ID: 9733483
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Methotrexate-alpha-phenylalanine: optimization of methotrexate prodrug for activation by carboxypeptidase A-monoclonal antibody conjugate.
    Vitols KS; Haag-Zeino B; Baer T; Montejano YD; Huennekens FM
    Cancer Res; 1995 Feb; 55(3):478-81. PubMed ID: 7834611
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular mechanisms of improvement of hydrolytic antibody 6D9 by site-directed mutagenesis.
    Takahashi-Ando N; Shimazaki K; Kakinuma H; Fujii I; Nishi Y
    J Biochem; 2006 Oct; 140(4):509-15. PubMed ID: 16921165
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.