These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

105 related articles for article (PubMed ID: 8507205)

  • 1. The catalytic activity of four expressed human cytochrome P450s towards benzo[a]pyrene and the isomers of its proximate carcinogen.
    Roberts-Thomson SJ; McManus ME; Tukey RH; Gonzalez FF; Holder GM
    Biochem Biophys Res Commun; 1993 May; 192(3):1373-9. PubMed ID: 8507205
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Roles of individual human cytochrome P-450 enzymes in the bioactivation of benzo(a)pyrene, 7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene, and other dihydrodiol derivatives of polycyclic aromatic hydrocarbons.
    Shimada T; Martin MV; Pruess-Schwartz D; Marnett LJ; Guengerich FP
    Cancer Res; 1989 Nov; 49(22):6304-12. PubMed ID: 2509067
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Contribution of human cytochrome P450 to benzo[a]pyrene and benzo[a]pyrene-7,8-dihydrodiol metabolism, as predicted from heterologous expression in yeast.
    Gautier JC; Lecoeur S; Cosme J; Perret A; Urban P; Beaune P; Pompon D
    Pharmacogenetics; 1996 Dec; 6(6):489-99. PubMed ID: 9014198
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The role of 12 cDNA-expressed human, rodent, and rabbit cytochromes P450 in the metabolism of benzo[a]pyrene and benzo[a]pyrene trans-7,8-dihydrodiol.
    Shou M; Korzekwa KR; Crespi CL; Gonzalez FJ; Gelboin HV
    Mol Carcinog; 1994 Jul; 10(3):159-68. PubMed ID: 8043197
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolism of benzo[a]pyrene to trans-7,8-dihydroxy-7, 8-dihydrobenzo[a]pyrene by recombinant human cytochrome P450 1B1 and purified liver epoxide hydrolase.
    Shimada T; Gillam EM; Oda Y; Tsumura F; Sutter TR; Guengerich FP; Inoue K
    Chem Res Toxicol; 1999 Jul; 12(7):623-9. PubMed ID: 10409402
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of benzo[a]pyrene and (+-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene on mitosis in Chinese hamster V79 cells with stable expression of rat cytochrome P4501A1 or 1A2.
    Jensen KG; Onfelt A; Poulsen HE; Doehmer J; Loft S
    Carcinogenesis; 1993 Oct; 14(10):2115-8. PubMed ID: 8222063
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Applications of stable V79-derived cell lines expressing rat cytochromes P4501A1, 1A2, and 2B1.
    Doehmer J; Wölfel C; Dogra S; Doehmer C; Seidel A; Platt KL; Oesch F; Glatt HR
    Xenobiotica; 1992; 22(9-10):1093-9. PubMed ID: 1441600
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1.
    Shimada T; Hayes CL; Yamazaki H; Amin S; Hecht SS; Guengerich FP; Sutter TR
    Cancer Res; 1996 Jul; 56(13):2979-84. PubMed ID: 8674051
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Metabolism of 5-methylchrysene and 6-methylchrysene by human hepatic and pulmonary cytochrome P450 enzymes.
    Koehl W; Amin S; Staretz ME; Ueng YF; Yamazaki H; Tateishi T; Guengerich FP; Hecht SS
    Cancer Res; 1996 Jan; 56(2):316-24. PubMed ID: 8542586
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A comparison of the intercalative binding of non-reactive benzo[a]pyrene metabolites and metabolite model compounds to DNA.
    Abramovich M; Prakash AS; Harvey RG; Zegar IS; Lebreton PR
    Chem Biol Interact; 1985 Oct; 55(1-2):39-62. PubMed ID: 3933843
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Roles of human liver cytochrome P4502C and 3A enzymes in the 3-hydroxylation of benzo(a)pyrene.
    Yun CH; Shimada T; Guengerich FP
    Cancer Res; 1992 Apr; 52(7):1868-74. PubMed ID: 1551116
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The time-dependent increase in the binding of benzo[a]pyrene to DNA through (+)-anti-benzo[a]pyrene-7,8-diol-9,10-epoxide in primary rat hepatocyte cultures results from induction of cytochrome P450IA1 by benzo[a]pyrene treatment.
    Eberhart J; Coffing SL; Anderson JN; Marcus C; Kalogeris TJ; Baird WM; Park SS; Gelboin HV
    Carcinogenesis; 1992 Feb; 13(2):297-301. PubMed ID: 1740021
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Analysis of benzo[a]pyrene deactivation mechanisms in rats.
    Sibirtsev VS
    Biochemistry (Mosc); 2006 Jan; 71(1):90-8. PubMed ID: 16457625
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Active site architecture of polymorphic forms of human glutathione S-transferase P1-1 accounts for their enantioselectivity and disparate activity in the glutathione conjugation of 7beta,8alpha-dihydroxy-9alpha,10alpha-ox y-7,8,9,10-tetrahydrobenzo(a)pyrene.
    Hu X; O'Donnell R; Srivastava SK; Xia H; Zimniak P; Nanduri B; Bleicher RJ; Awasthi S; Awasthi YC; Ji X; Singh SV
    Biochem Biophys Res Commun; 1997 Jun; 235(2):424-8. PubMed ID: 9199210
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metabolic activation of the potent carcinogen dibenzo[a,h]anthracene by cDNA-expressed human cytochromes P450.
    Shou M; Krausz KW; Gonzalez FJ; Gelboin HV
    Arch Biochem Biophys; 1996 Apr; 328(1):201-7. PubMed ID: 8638931
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Benzo(a)pyrene activation to 7,8-dihydrodiol 9,10-oxide by rat liver microsomes. Control by selective product inhibition.
    Keller GM; Jefcoate CR
    J Biol Chem; 1984 Nov; 259(22):13770-6. PubMed ID: 6438082
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Competing roles of cytochrome P450 1A1/1B1 and aldo-keto reductase 1A1 in the metabolic activation of (+/-)-7,8-dihydroxy-7,8-dihydro-benzo[a]pyrene in human bronchoalveolar cell extracts.
    Jiang H; Shen YM; Quinn AM; Penning TM
    Chem Res Toxicol; 2005 Feb; 18(2):365-74. PubMed ID: 15720144
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metabolism of polycyclic aza-aromatic carcinogens catalyzed by four expressed human cytochromes P450.
    Roberts-Thomson SJ; McManus ME; Tukey RH; Gonzalez FJ; Holder GM
    Cancer Res; 1995 Mar; 55(5):1052-9. PubMed ID: 7866988
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Specificity of cDNA-expressed human and rodent cytochrome P450s in the oxidative metabolism of the potent carcinogen 7,12-dimethylbenz[a]anthracene.
    Shou M; Korzekwa KR; Krausz KW; Buters JT; Grogan J; Goldfarb I; Hardwick JP; Gonzalez FJ; Gelboin HV
    Mol Carcinog; 1996 Dec; 17(4):241-9. PubMed ID: 8989918
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Expression of human cytochrome P450 1A1 in DNA repair deficient and proficient human fibroblasts stably transformed with an inducible expression vector.
    States JC; Quan T; Hines RN; Novak RF; Runge-Morris M
    Carcinogenesis; 1993 Aug; 14(8):1643-9. PubMed ID: 8353849
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.