These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

82 related articles for article (PubMed ID: 8510006)

  • 1. Dose- and time-dependent changes in phencyclidine metabolite covalent binding in rats and the possible role of CYP2D1.
    Owens SM; Gunnell M; Laurenzana EM; Valentine JL
    J Pharmacol Exp Ther; 1993 Jun; 265(3):1261-6. PubMed ID: 8510006
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolism of phencyclidine by human liver microsomes.
    Laurenzana EM; Owens SM
    Drug Metab Dispos; 1997 May; 25(5):557-63. PubMed ID: 9152594
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inactivation of constitutive hepatic cytochromes P450 by phencyclidine in the rat.
    Hiratsuka A; Chu TY; Distefano EW; Lin LY; Schmitz DA; Cho AK
    Drug Metab Dispos; 1995 Feb; 23(2):201-6. PubMed ID: 7736912
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA
    Toxic Rep Ser; 1999 Aug; (59):1-66, A1-E7. PubMed ID: 11803702
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phencyclidine dependence: the relationship of dose and serum concentrations to operant behavioral effects.
    Wessinger WD; Owens SM
    J Pharmacol Exp Ther; 1991 Jul; 258(1):207-15. PubMed ID: 2072296
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differences in cytochrome P450-mediated biotransformation of 1,2-dichlorobenzene by rat and man: implications for human risk assessment.
    Hissink AM; Oudshoorn MJ; Van Ommen B; Haenen GR; Van Bladeren PJ
    Chem Res Toxicol; 1996 Dec; 9(8):1249-56. PubMed ID: 8951226
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phencyclidine iminium ion. NADPH-dependent metabolism, covalent binding to macromolecules, and inactivation of cytochrome(s) P-450.
    Hoag MK; Trevor AJ; Kalir A; Castagnoli N
    Drug Metab Dispos; 1987; 15(4):485-90. PubMed ID: 2888621
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phencyclidine continuous dosing produces a treatment time-dependent regulation of rat CYP2C11 function, protein expression and mRNA levels.
    Shelnutt SR; Cornett LE; Owens SM
    J Pharmacol Exp Ther; 1997 Apr; 281(1):574-81. PubMed ID: 9103546
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Anti-phencyclidine monoclonal antibodies provide long-term reductions in brain phencyclidine concentrations during chronic phencyclidine administration in rats.
    Proksch JW; Gentry WB; Owens SM
    J Pharmacol Exp Ther; 2000 Mar; 292(3):831-7. PubMed ID: 10688594
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Metabolism-dependent inactivation of liver microsomal enzymes by phencyclidine.
    Hoag MK; Trevor AJ; Asscher Y; Weissman J; Castagnoli N
    Drug Metab Dispos; 1984; 12(3):371-5. PubMed ID: 6145566
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanism-based inactivation of rat liver cytochrome P4502B1 by phencyclidine and its oxidative product, the iminium ion.
    Crowley JR; Hollenberg PF
    Drug Metab Dispos; 1995 Aug; 23(8):786-93. PubMed ID: 7493543
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Microsomal oxidation of N,N-diethylformamide and its effect on P450-dependent monooxygenases in rat liver.
    Amato G; Longo V; Mazzaccaro A; Gervasi PG
    Chem Res Toxicol; 1996; 9(5):882-90. PubMed ID: 8828925
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Preclinical pharmacokinetics and metabolism of 6-(4-(2,5-difluorophenyl)oxazol-5-yl)-3-isopropyl-[1,2,4]-triazolo[4,3-a]pyridine, a novel and selective p38alpha inhibitor: identification of an active metabolite in preclinical species and human liver microsomes.
    Kalgutkar AS; Hatch HL; Kosea F; Nguyen HT; Choo EF; McClure KF; Taylor TJ; Henne KR; Kuperman AV; Dombroski MA; Letavic MA
    Biopharm Drug Dispos; 2006 Nov; 27(8):371-86. PubMed ID: 16944451
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Metabolic activation of diclofenac by human cytochrome P450 3A4: role of 5-hydroxydiclofenac.
    Shen S; Marchick MR; Davis MR; Doss GA; Pohl LR
    Chem Res Toxicol; 1999 Feb; 12(2):214-22. PubMed ID: 10027801
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antiphencyclidine monoclonal antibody therapy significantly changes phencyclidine concentrations in brain and other tissues in rats.
    Valentine JL; Owens SM
    J Pharmacol Exp Ther; 1996 Aug; 278(2):717-24. PubMed ID: 8768723
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of chronic exposure to cadmium on renal cytochrome P450-dependent monooxygenase system in rats.
    Plewka A; Plewka D; Nowaczyk G; Brzóska MM; Kamiński M; Moniuszko-Jakoniuk J
    Arch Toxicol; 2004 Apr; 78(4):194-200. PubMed ID: 14595535
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antiphencyclidine monoclonal Fab fragments reverse phencyclidine-induced behavioral effects and ataxia in rats.
    Valentine JL; Mayersohn M; Wessinger WD; Arnold LW; Owens SM
    J Pharmacol Exp Ther; 1996 Aug; 278(2):709-16. PubMed ID: 8768722
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Aryl acetylenes as mechanism-based inhibitors of cytochrome P450-dependent monooxygenase enzymes.
    Foroozesh M; Primrose G; Guo Z; Bell LC; Alworth WL; Guengerich FP
    Chem Res Toxicol; 1997 Jan; 10(1):91-102. PubMed ID: 9074808
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of the anticancer dehydrotarplatin on cytochrome P450 and antioxidant enzymes in male rat tissues.
    Nannelli A; Messina A; Marini S; Trasciatti S; Longo V; Gervasi PG
    Arch Toxicol; 2007 Jul; 81(7):479-87. PubMed ID: 17364183
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The effect of rate of drug administration on the extent and time course of phencyclidine distribution in rat brain, testis, and serum.
    Proksch JW; Gentry WB; Owens SM
    Drug Metab Dispos; 2000 Jul; 28(7):742-7. PubMed ID: 10859146
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.