BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

282 related articles for article (PubMed ID: 8519781)

  • 1. The pleckstrin homology domain of phospholipase C-delta 1 binds with high affinity to phosphatidylinositol 4,5-bisphosphate in bilayer membranes.
    Garcia P; Gupta R; Shah S; Morris AJ; Rudge SA; Scarlata S; Petrova V; McLaughlin S; Rebecchi MJ
    Biochemistry; 1995 Dec; 34(49):16228-34. PubMed ID: 8519781
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Replacements of single basic amino acids in the pleckstrin homology domain of phospholipase C-delta1 alter the ligand binding, phospholipase activity, and interaction with the plasma membrane.
    Yagisawa H; Sakuma K; Paterson HF; Cheung R; Allen V; Hirata H; Watanabe Y; Hirata M; Williams RL; Katan M
    J Biol Chem; 1998 Jan; 273(1):417-24. PubMed ID: 9417098
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A single amino acid substitution in the pleckstrin homology domain of phospholipase C delta1 enhances the rate of substrate hydrolysis.
    Bromann PA; Boetticher EE; Lomasney JW
    J Biol Chem; 1997 Jun; 272(26):16240-6. PubMed ID: 9195925
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential association of the pleckstrin homology domains of phospholipases C-beta 1, C-beta 2, and C-delta 1 with lipid bilayers and the beta gamma subunits of heterotrimeric G proteins.
    Wang T; Pentyala S; Rebecchi MJ; Scarlata S
    Biochemistry; 1999 Feb; 38(5):1517-24. PubMed ID: 9931017
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phosphatidylinositol 4,5-bisphosphate binding to the pleckstrin homology domain of phospholipase C-delta1 enhances enzyme activity.
    Lomasney JW; Cheng HF; Wang LP; Kuan Y; Liu S; Fesik SW; King K
    J Biol Chem; 1996 Oct; 271(41):25316-26. PubMed ID: 8810295
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain.
    Lemmon MA; Ferguson KM; O'Brien R; Sigler PB; Schlessinger J
    Proc Natl Acad Sci U S A; 1995 Nov; 92(23):10472-6. PubMed ID: 7479822
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Pleckstrin homology domains of phospholipases C-beta and -delta confer activation through a common site.
    Guo Y; Philip F; Scarlata S
    J Biol Chem; 2003 Aug; 278(32):29995-30004. PubMed ID: 12761218
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular modeling of the membrane targeting of phospholipase C pleckstrin homology domains.
    Singh SM; Murray D
    Protein Sci; 2003 Sep; 12(9):1934-53. PubMed ID: 12930993
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Group IV cytosolic phospholipase A2 binds with high affinity and specificity to phosphatidylinositol 4,5-bisphosphate resulting in dramatic increases in activity.
    Mosior M; Six DA; Dennis EA
    J Biol Chem; 1998 Jan; 273(4):2184-91. PubMed ID: 9442060
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inositol lipid binding and membrane localization of isolated pleckstrin homology (PH) domains. Studies on the PH domains of phospholipase C delta 1 and p130.
    Várnai P; Lin X; Lee SB; Tuymetova G; Bondeva T; Spät A; Rhee SG; Hajnóczky G; Balla T
    J Biol Chem; 2002 Jul; 277(30):27412-22. PubMed ID: 12019260
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The pleckstrin homology domain of phosphoinositide-specific phospholipase Cdelta4 is not a critical determinant of the membrane localization of the enzyme.
    Lee SB; Várnai P; Balla A; Jalink K; Rhee SG; Balla T
    J Biol Chem; 2004 Jun; 279(23):24362-71. PubMed ID: 15037625
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cloning and identification of amino acid residues of human phospholipase C delta 1 essential for catalysis.
    Cheng HF; Jiang MJ; Chen CL; Liu SM; Wong LP; Lomasney JW; King K
    J Biol Chem; 1995 Mar; 270(10):5495-505. PubMed ID: 7890667
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Involvement of EF hand motifs in the Ca(2+)-dependent binding of the pleckstrin homology domain to phosphoinositides.
    Yamamoto T; Takeuchi H; Kanematsu T; Allen V; Yagisawa H; Kikkawa U; Watanabe Y; Nakasima A; Katan M; Hirata M
    Eur J Biochem; 1999 Oct; 265(1):481-90. PubMed ID: 10491207
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interaction of elongation factor-1alpha and pleckstrin homology domain of phospholipase C-gamma 1 with activating its activity.
    Chang JS; Seok H; Kwon TK; Min DS; Ahn BH; Lee YH; Suh JW; Kim JW; Iwashita S; Omori A; Ichinose S; Numata O; Seo JK; Oh YS; Suh PG
    J Biol Chem; 2002 May; 277(22):19697-702. PubMed ID: 11886851
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Expression and characterization of an inositol 1,4,5-trisphosphate binding domain of phosphatidylinositol-specific phospholipase C-delta 1.
    Yagisawa H; Hirata M; Kanematsu T; Watanabe Y; Ozaki S; Sakuma K; Tanaka H; Yabuta N; Kamata H; Hirata H
    J Biol Chem; 1994 Aug; 269(31):20179-88. PubMed ID: 8051106
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure of the high affinity complex of inositol trisphosphate with a phospholipase C pleckstrin homology domain.
    Ferguson KM; Lemmon MA; Schlessinger J; Sigler PB
    Cell; 1995 Dec; 83(6):1037-46. PubMed ID: 8521504
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phosphoinositide binding specificity among phospholipase C isozymes as determined by photo-cross-linking to novel substrate and product analogs.
    Tall E; Dormán G; Garcia P; Runnels L; Shah S; Chen J; Profit A; Gu QM; Chaudhary A; Prestwich GD; Rebecchi MJ
    Biochemistry; 1997 Jun; 36(23):7239-48. PubMed ID: 9188725
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutation in the pleckstrin homology domain of the human phospholipase C-delta 1 gene is associated with loss of function.
    Shimohama S; Kamiya S; Fujii M; Ogawa T; Kanamori M; Kawamata J; Imura T; Taniguchi T; Yagisawa H
    Biochem Biophys Res Commun; 1998 Apr; 245(3):722-8. PubMed ID: 9588182
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Membrane activity of the phospholipase C-delta1 pleckstrin homology (PH) domain.
    Flesch FM; Yu JW; Lemmon MA; Burger KN
    Biochem J; 2005 Jul; 389(Pt 2):435-41. PubMed ID: 15755258
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pollen tube tip growth depends on plasma membrane polarization mediated by tobacco PLC3 activity and endocytic membrane recycling.
    Helling D; Possart A; Cottier S; Klahre U; Kost B
    Plant Cell; 2006 Dec; 18(12):3519-34. PubMed ID: 17172355
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.