These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

296 related articles for article (PubMed ID: 8521504)

  • 1. Structure of the high affinity complex of inositol trisphosphate with a phospholipase C pleckstrin homology domain.
    Ferguson KM; Lemmon MA; Schlessinger J; Sigler PB
    Cell; 1995 Dec; 83(6):1037-46. PubMed ID: 8521504
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain.
    Lemmon MA; Ferguson KM; O'Brien R; Sigler PB; Schlessinger J
    Proc Natl Acad Sci U S A; 1995 Nov; 92(23):10472-6. PubMed ID: 7479822
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Replacements of single basic amino acids in the pleckstrin homology domain of phospholipase C-delta1 alter the ligand binding, phospholipase activity, and interaction with the plasma membrane.
    Yagisawa H; Sakuma K; Paterson HF; Cheung R; Allen V; Hirata H; Watanabe Y; Hirata M; Williams RL; Katan M
    J Biol Chem; 1998 Jan; 273(1):417-24. PubMed ID: 9417098
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Expression and characterization of an inositol 1,4,5-trisphosphate binding domain of phosphatidylinositol-specific phospholipase C-delta 1.
    Yagisawa H; Hirata M; Kanematsu T; Watanabe Y; Ozaki S; Sakuma K; Tanaka H; Yabuta N; Kamata H; Hirata H
    J Biol Chem; 1994 Aug; 269(31):20179-88. PubMed ID: 8051106
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure of the PH domain from Bruton's tyrosine kinase in complex with inositol 1,3,4,5-tetrakisphosphate.
    Baraldi E; Djinovic Carugo K; Hyvönen M; Surdo PL; Riley AM; Potter BV; O'Brien R; Ladbury JE; Saraste M
    Structure; 1999 Apr; 7(4):449-60. PubMed ID: 10196129
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The pleckstrin homology domain of phospholipase C-delta 1 binds with high affinity to phosphatidylinositol 4,5-bisphosphate in bilayer membranes.
    Garcia P; Gupta R; Shah S; Morris AJ; Rudge SA; Scarlata S; Petrova V; McLaughlin S; Rebecchi MJ
    Biochemistry; 1995 Dec; 34(49):16228-34. PubMed ID: 8519781
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure of the PH domain and Btk motif from Bruton's tyrosine kinase: molecular explanations for X-linked agammaglobulinaemia.
    Hyvönen M; Saraste M
    EMBO J; 1997 Jun; 16(12):3396-404. PubMed ID: 9218782
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutation in the pleckstrin homology domain of the human phospholipase C-delta 1 gene is associated with loss of function.
    Shimohama S; Kamiya S; Fujii M; Ogawa T; Kanamori M; Kawamata J; Imura T; Taniguchi T; Yagisawa H
    Biochem Biophys Res Commun; 1998 Apr; 245(3):722-8. PubMed ID: 9588182
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phospholipase C delta 1 requires a pleckstrin homology domain for interaction with the plasma membrane.
    Paterson HF; Savopoulos JW; Perisic O; Cheung R; Ellis MV; Williams RL; Katan M
    Biochem J; 1995 Dec; 312 ( Pt 3)(Pt 3):661-6. PubMed ID: 8554502
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The pleckstrin homology domain of phosphoinositide-specific phospholipase Cdelta4 is not a critical determinant of the membrane localization of the enzyme.
    Lee SB; Várnai P; Balla A; Jalink K; Rhee SG; Balla T
    J Biol Chem; 2004 Jun; 279(23):24362-71. PubMed ID: 15037625
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Localization of a high-affinity inositol 1,4,5-trisphosphate/inositol 1,4,5,6-tetrakisphosphate binding domain to the pleckstrin homology module of a new 130 kDa protein: characterization of the determinants of structural specificity.
    Takeuchi H; Kanematsu T; Misumi Y; Yaakob HB; Yagisawa H; Ikehara Y; Watanabe Y; Tan Z; Shears SB; Hirata M
    Biochem J; 1996 Sep; 318 ( Pt 2)(Pt 2):561-8. PubMed ID: 8809047
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular modeling of the membrane targeting of phospholipase C pleckstrin homology domains.
    Singh SM; Murray D
    Protein Sci; 2003 Sep; 12(9):1934-53. PubMed ID: 12930993
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Solution structure of the pleckstrin homology domain of Drosophila beta-spectrin.
    Zhang P; Talluri S; Deng H; Branton D; Wagner G
    Structure; 1995 Nov; 3(11):1185-95. PubMed ID: 8591029
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Specificity and promiscuity in phosphoinositide binding by pleckstrin homology domains.
    Kavran JM; Klein DE; Lee A; Falasca M; Isakoff SJ; Skolnik EY; Lemmon MA
    J Biol Chem; 1998 Nov; 273(46):30497-508. PubMed ID: 9804818
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Functional reassembly of a split PH domain.
    Sugimoto K; Mori Y; Makino K; Ohkubo K; Morii T
    J Am Chem Soc; 2003 Apr; 125(17):5000-4. PubMed ID: 12708849
    [TBL] [Abstract][Full Text] [Related]  

  • 16. D-myo-inositol 1,4,5-trisphosphate binding domain of phospholipase C-delta 1.
    Hirata M; Kanematsu T; Sakuma K; Koga T; Watanabe Y; Ozaki S; Yagisawa H
    Biochem Biophys Res Commun; 1994 Dec; 205(3):1563-71. PubMed ID: 7811237
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interaction of elongation factor-1alpha and pleckstrin homology domain of phospholipase C-gamma 1 with activating its activity.
    Chang JS; Seok H; Kwon TK; Min DS; Ahn BH; Lee YH; Suh JW; Kim JW; Iwashita S; Omori A; Ichinose S; Numata O; Seo JK; Oh YS; Suh PG
    J Biol Chem; 2002 May; 277(22):19697-702. PubMed ID: 11886851
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A new fluorescent biosensor for inositol trisphosphate.
    Morii T; Sugimoto K; Makino K; Otsuka M; Imoto K; Mori Y
    J Am Chem Soc; 2002 Feb; 124(7):1138-9. PubMed ID: 11841260
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inositol lipid binding and membrane localization of isolated pleckstrin homology (PH) domains. Studies on the PH domains of phospholipase C delta 1 and p130.
    Várnai P; Lin X; Lee SB; Tuymetova G; Bondeva T; Spät A; Rhee SG; Hajnóczky G; Balla T
    J Biol Chem; 2002 Jul; 277(30):27412-22. PubMed ID: 12019260
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular modelling and site-directed mutagenesis of the inositol 1,3,4,5-tetrakisphosphate-binding pleckstrin homology domain from the Ras GTPase-activating protein GAP1IP4BP.
    Cozier G; Sessions R; Bottomley JR; Reynolds JS; Cullen PJ
    Biochem J; 2000 Jul; 349(Pt 1):333-42. PubMed ID: 10861245
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.