BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

213 related articles for article (PubMed ID: 8524316)

  • 1. Roles of JAKs in activation of STATs and stimulation of c-fos gene expression by epidermal growth factor.
    Leaman DW; Pisharody S; Flickinger TW; Commane MA; Schlessinger J; Kerr IM; Levy DE; Stark GR
    Mol Cell Biol; 1996 Jan; 16(1):369-75. PubMed ID: 8524316
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phosphorylation and activation of the DNA binding activity of purified Stat1 by the Janus protein-tyrosine kinases and the epidermal growth factor receptor.
    Quelle FW; Thierfelder W; Witthuhn BA; Tang B; Cohen S; Ihle JN
    J Biol Chem; 1995 Sep; 270(35):20775-80. PubMed ID: 7657660
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Beta interferon and oncostatin M activate Raf-1 and mitogen-activated protein kinase through a JAK1-dependent pathway.
    Stancato LF; Sakatsume M; David M; Dent P; Dong F; Petricoin EF; Krolewski JJ; Silvennoinen O; Saharinen P; Pierce J; Marshall CJ; Sturgill T; Finbloom DS; Larner AC
    Mol Cell Biol; 1997 Jul; 17(7):3833-40. PubMed ID: 9199317
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Unexpected transcriptional signals in normal and mitotically defective cells mediated through cytokine and growth factor receptors.
    Samanta A; Qian X; Greene MI
    DNA Cell Biol; 1995 Nov; 14(11):921-30. PubMed ID: 7576178
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteins.
    Vignais ML; Sadowski HB; Watling D; Rogers NC; Gilman M
    Mol Cell Biol; 1996 Apr; 16(4):1759-69. PubMed ID: 8657151
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases.
    Olayioye MA; Beuvink I; Horsch K; Daly JM; Hynes NE
    J Biol Chem; 1999 Jun; 274(24):17209-18. PubMed ID: 10358079
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Jak1 plays an essential role for receptor phosphorylation and Stat activation in response to granulocyte colony-stimulating factor.
    Shimoda K; Feng J; Murakami H; Nagata S; Watling D; Rogers NC; Stark GR; Kerr IM; Ihle JN
    Blood; 1997 Jul; 90(2):597-604. PubMed ID: 9226159
    [TBL] [Abstract][Full Text] [Related]  

  • 8. STAT activation by epidermal growth factor (EGF) and amphiregulin. Requirement for the EGF receptor kinase but not for tyrosine phosphorylation sites or JAK1.
    David M; Wong L; Flavell R; Thompson SA; Wells A; Larner AC; Johnson GR
    J Biol Chem; 1996 Apr; 271(16):9185-8. PubMed ID: 8621573
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [H2O2-induced activation of transcription factors STAT1 and STAT3: the role of EGF receptor and tyrosine kinase JAK2].
    Burova EB; Grudinkin PS; Bardin AA; Gamaleĭ NN
    Tsitologiia; 2001; 43(12):1153-61. PubMed ID: 11881154
    [TBL] [Abstract][Full Text] [Related]  

  • 10. An epidermal growth factor receptor/Jak2 tyrosine kinase domain chimera induces tyrosine phosphorylation of Stat5 and transduces a growth signal in hematopoietic cells.
    Nakamura N; Chin H; Miyasaka N; Miura O
    J Biol Chem; 1996 Aug; 271(32):19483-8. PubMed ID: 8702638
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of Stat3 in v-Src-transformed fibroblasts requires cooperation of Jak1 kinase activity.
    Zhang Y; Turkson J; Carter-Su C; Smithgall T; Levitzki A; Kraker A; Krolewski JJ; Medveczky P; Jove R
    J Biol Chem; 2000 Aug; 275(32):24935-44. PubMed ID: 10823829
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl.
    Carlesso N; Frank DA; Griffin JD
    J Exp Med; 1996 Mar; 183(3):811-20. PubMed ID: 8642285
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6.
    Guschin D; Rogers N; Briscoe J; Witthuhn B; Watling D; Horn F; Pellegrini S; Yasukawa K; Heinrich P; Stark GR
    EMBO J; 1995 Apr; 14(7):1421-9. PubMed ID: 7537214
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3, and 5 by GH.
    Smit LS; Meyer DJ; Billestrup N; Norstedt G; Schwartz J; Carter-Su C
    Mol Endocrinol; 1996 May; 10(5):519-33. PubMed ID: 8732683
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activation of JAK kinases and STAT proteins by interleukin-2 and interferon alpha, but not the T cell antigen receptor, in human T lymphocytes.
    Beadling C; Guschin D; Witthuhn BA; Ziemiecki A; Ihle JN; Kerr IM; Cantrell DA
    EMBO J; 1994 Dec; 13(23):5605-15. PubMed ID: 7988557
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis.
    Chin YE; Kitagawa M; Kuida K; Flavell RA; Fu XY
    Mol Cell Biol; 1997 Sep; 17(9):5328-37. PubMed ID: 9271410
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The JAK-inhibitor, JAB/SOCS-1 selectively inhibits cytokine-induced, but not v-Src induced JAK-STAT activation.
    Iwamoto T; Senga T; Naito Y; Matsuda S; Miyake Y; Yoshimura A; Hamaguchi M
    Oncogene; 2000 Sep; 19(41):4795-801. PubMed ID: 11032030
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Kinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral state.
    Briscoe J; Rogers NC; Witthuhn BA; Watling D; Harpur AG; Wilks AF; Stark GR; Ihle JN; Kerr IM
    EMBO J; 1996 Feb; 15(4):799-809. PubMed ID: 8631301
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interleukin-7 signaling in human B cell precursor acute lymphoblastic leukemia cells and murine BAF3 cells involves activation of STAT1 and STAT5 mediated via the interleukin-7 receptor alpha chain.
    van der Plas DC; Smiers F; Pouwels K; Hoefsloot LH; Löwenberg B; Touw IP
    Leukemia; 1996 Aug; 10(8):1317-25. PubMed ID: 8709637
    [TBL] [Abstract][Full Text] [Related]  

  • 20. An alternative pathway for STAT activation that is mediated by the direct interaction between JAK and STAT.
    Fujitani Y; Hibi M; Fukada T; Takahashi-Tezuka M; Yoshida H; Yamaguchi T; Sugiyama K; Yamanaka Y; Nakajima K; Hirano T
    Oncogene; 1997 Feb; 14(7):751-61. PubMed ID: 9047382
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.