BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

350 related articles for article (PubMed ID: 8526876)

  • 21. 5'-O-Methylphosphonate nucleic acids--new modified DNAs that increase the Escherichia coli RNase H cleavage rate of hybrid duplexes.
    Šipova H; Špringer T; Rejman D; Šimak O; Petrová M; Novák P; Rosenbergová Š; Páv O; Liboska R; Barvík I; Štěpanek J; Rosenberg I; Homola J
    Nucleic Acids Res; 2014 Apr; 42(8):5378-89. PubMed ID: 24523351
    [TBL] [Abstract][Full Text] [Related]  

  • 22. A critical survey of the structure-function of the antisense oligo/RNA heteroduplex as substrate for RNase H.
    Zamaratski E; Pradeepkumar PI; Chattopadhyaya J
    J Biochem Biophys Methods; 2001 May; 48(3):189-208. PubMed ID: 11384757
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Impact of mixed-backbone oligonucleotides on target binding affinity and target cleaving specificity and selectivity by Escherichia coli RNase H.
    Shen LX; Kandimalla ER; Agrawal S
    Bioorg Med Chem; 1998 Oct; 6(10):1695-705. PubMed ID: 9839001
    [TBL] [Abstract][Full Text] [Related]  

  • 24. [Cleavage of RNA in hybrid duplexes by E. coli ribonuclease H. II. Substrate properties of nucleotides containing non-nucleotide linkers].
    Vorob'ev PE; Pyshnaia IA; Pyshnyĭ DV; Repkova MN; Ven'iaminov AG; Zenkova MA; Ivanova EM; Scalfi-Happ C; Seliger H; Bonora G; Zarytova VF
    Bioorg Khim; 2000 Nov; 26(11):844-51. PubMed ID: 11696895
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Molecular requirements for degradation of a modified sense RNA strand by Escherichia coli ribonuclease H1.
    Yazbeck DR; Min KL; Damha MJ
    Nucleic Acids Res; 2002 Jul; 30(14):3015-25. PubMed ID: 12136083
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Correlation of selective modifications to a 2',5'-oligoadenylate-3',5'-deoxyribonucleotide antisense chimera with affinity for the target nucleic acid and with ability to activate RNase L.
    Xiao W; Li G; Maitra RK; Maran A; Silverman RH; Torrence PF
    J Med Chem; 1997 Apr; 40(8):1195-200. PubMed ID: 9111293
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Helix-stabilizing compounds CC-1065 and U-71,184 bind to RNA-DNA and DNA-DNA duplexes containing modified internucleotide linkages and stabilize duplexes against thermal melting.
    Kim DY; Shih DS; Cho DY; Swenson DH
    Antisense Res Dev; 1995; 5(1):49-57. PubMed ID: 7542048
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Induction of RNase H activity by Arabinose-peptide nucleic acid chimeras.
    Pâtureau BM; Hudson RH; Damha MJ
    Bioconjug Chem; 2007; 18(2):421-30. PubMed ID: 17373768
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Phosphorothioate oligonucleotides block reverse transcription by the Rnase H activity associated with the HIV-1 polymerase.
    Hatta T; Takai K; Yokoyama S; Nakashima H; Yamamoto N; Takaku H
    Biochem Biophys Res Commun; 1995 Jun; 211(3):1041-6. PubMed ID: 7541196
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Evaluation of 2'-modified oligonucleotides containing 2'-deoxy gaps as antisense inhibitors of gene expression.
    Monia BP; Lesnik EA; Gonzalez C; Lima WF; McGee D; Guinosso CJ; Kawasaki AM; Cook PD; Freier SM
    J Biol Chem; 1993 Jul; 268(19):14514-22. PubMed ID: 8390996
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Solution structure of an arabinonucleic acid (ANA)/RNA duplex in a chimeric hairpin: comparison with 2'-fluoro-ANA/RNA and DNA/RNA hybrids.
    Denisov AY; Noronha AM; Wilds CJ; Trempe JF; Pon RT; Gehring K; Damha MJ
    Nucleic Acids Res; 2001 Nov; 29(21):4284-93. PubMed ID: 11691916
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Increased specificity for antisense oligodeoxynucleotide targeting of RNA cleavage by RNase H using chimeric methylphosphonodiester/phosphodiester structures.
    Giles RV; Tidd DM
    Nucleic Acids Res; 1992 Feb; 20(4):763-70. PubMed ID: 1371864
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Identifying and avoiding off-target effects of RNase H-dependent antisense oligonucleotides in mice.
    Hagedorn PH; Pontoppidan M; Bisgaard TS; Berrera M; Dieckmann A; Ebeling M; Møller MR; Hudlebusch H; Jensen ML; Hansen HF; Koch T; Lindow M
    Nucleic Acids Res; 2018 Jun; 46(11):5366-5380. PubMed ID: 29790953
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Cleavage of single strand RNA adjacent to RNA-DNA duplex regions by Escherichia coli RNase H1.
    Lima WF; Crooke ST
    J Biol Chem; 1997 Oct; 272(44):27513-6. PubMed ID: 9346880
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Design of antisense oligonucleotides stabilized by locked nucleic acids.
    Kurreck J; Wyszko E; Gillen C; Erdmann VA
    Nucleic Acids Res; 2002 May; 30(9):1911-8. PubMed ID: 11972327
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Modulation of RNase H activity by modified DNA probes: major groove vs minor groove effects.
    Daniher AT; Xie J; Mathur S; Bashkin JK
    Bioorg Med Chem; 1997 Jun; 5(6):1037-42. PubMed ID: 9222496
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Gapmer Antisense Oligonucleotides Containing 2',3'-Dideoxy-2'-fluoro-3'-C-hydroxymethyl-β-d-lyxofuranosyl Nucleotides Display Site-Specific RNase H Cleavage and Induce Gene Silencing.
    Danielsen MB; Lou C; Lisowiec-Wachnicka J; Pasternak A; Jørgensen PT; Wengel J
    Chemistry; 2020 Jan; 26(6):1368-1379. PubMed ID: 31682037
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The use of oligonucleotide probes containing 2'-deoxy-2'-fluoronucleosides for regiospecific cleavage of RNA by RNase H from Escherichia coli.
    Schmidt S; Niemann A; Krynetskaya NF; Oretskaya TS; Metelev VG; Suchomlinov VV; Shabarova ZA; Cech D
    Biochim Biophys Acta; 1992 Feb; 1130(1):41-6. PubMed ID: 1371935
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Crystal structures of RNase H bound to an RNA/DNA hybrid: substrate specificity and metal-dependent catalysis.
    Nowotny M; Gaidamakov SA; Crouch RJ; Yang W
    Cell; 2005 Jul; 121(7):1005-16. PubMed ID: 15989951
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Phosphorothioate oligonucleotides are inhibitors of human DNA polymerases and RNase H: implications for antisense technology.
    Gao WY; Han FS; Storm C; Egan W; Cheng YC
    Mol Pharmacol; 1992 Feb; 41(2):223-9. PubMed ID: 1371582
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 18.