These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

109 related articles for article (PubMed ID: 8527866)

  • 1. Screening of colon tumor cells and tissues for folylpolyglutamate synthetase activity.
    van der Wilt CL; Cloos J; de Jong M; Pinedo HM; Peters GJ
    Oncol Res; 1995; 7(6):317-21. PubMed ID: 8527866
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Decreased folylpolyglutamate synthetase activity in tumors resistant to fluorouracil-folinic acid treatment: clinical data.
    Chazal M; Cheradame S; Formento JL; Francoual M; Formento P; Etienne MC; François E; Richelme H; Mousseau M; Letoublon C; Pezet D; Cure H; Seitz JF; Milano G
    Clin Cancer Res; 1997 Apr; 3(4):553-7. PubMed ID: 9815719
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines.
    van Triest B; Pinedo HM; van Hensbergen Y; Smid K; Telleman F; Schoenmakers PS; van der Wilt CL; van Laar JA; Noordhuis P; Jansen G; Peters GJ
    Clin Cancer Res; 1999 Mar; 5(3):643-54. PubMed ID: 10100718
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of folylpolyglutamate synthetase modulation on chemosensitivity of colon cancer cells to 5-fluorouracil and methotrexate.
    Sohn KJ; Smirnakis F; Moskovitz DN; Novakovic P; Yates Z; Lucock M; Croxford R; Kim YI
    Gut; 2004 Dec; 53(12):1825-31. PubMed ID: 15542523
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of folylpolyglutamate synthetase in the regulation of methotrexate polyglutamate formation in H35 hepatoma cells.
    Johnson TB; Nair MG; Galivan J
    Cancer Res; 1988 May; 48(9):2426-31. PubMed ID: 2451560
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differing specificities for 4-aminofolate analogues of folylpolyglutamyl synthetase from tumors and proliferative intestinal epithelium of the mouse with significance for selective antitumor action.
    Rumberger BG; Barrueco JR; Sirotnak FM
    Cancer Res; 1990 Aug; 50(15):4639-43. PubMed ID: 2369741
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Quantitative analysis of folylpolyglutamate synthetase gene expression in tumor tissues by the polymerase chain reaction: marked variation of expression among leukemia patients.
    Lenz HJ; Danenberg K; Schnieders B; Goeker E; Peters GJ; Garrow T; Shane B; Bertino JR; Danenberg PV
    Oncol Res; 1994; 6(7):329-35. PubMed ID: 7865908
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DL-beta,beta-difluoroglutamic acid mediates position-dependent enhancement or termination of pteroylpoly(gamma-glutamate) synthesis catalyzed by folylpolyglutamate synthetase.
    McGuire JJ; Hart BP; Haile WH; Rhee MS; Galivan J; Coward JK
    Arch Biochem Biophys; 1995 Aug; 321(2):319-28. PubMed ID: 7646057
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Folylpolyglutamate synthetase expression in antifolate-sensitive and -resistant human cell lines.
    McGuire JJ; Russell CA
    Oncol Res; 1998; 10(4):193-200. PubMed ID: 9778690
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Folate analogues as substrates of mammalian folylpolyglutamate synthetase.
    Schoo MM; Pristupa ZB; Vickers PJ; Scrimgeour KG
    Cancer Res; 1985 Jul; 45(7):3034-41. PubMed ID: 3873989
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Measurement of folylpolyglutamate synthetase activity in head and neck squamous carcinoma cell lines and clinical samples using a new rapid separation procedure.
    Jansen G; Schornagel JH; Kathmann I; Westerhof GR; Hordijk GJ; van der Laan BF
    Oncol Res; 1992; 4(7):299-305. PubMed ID: 1450491
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Determinants of antifolate cytotoxicity: folylpolyglutamate synthetase activity during cellular proliferation and development.
    Barredo J; Moran RG
    Mol Pharmacol; 1992 Oct; 42(4):687-94. PubMed ID: 1435744
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural requirements for the activity of antifolates as substrates for mammalian folylpolyglutamate synthetase.
    Moran RG; Colman PD; Rosowsky A
    NCI Monogr; 1987; (5):133-8. PubMed ID: 2448651
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Folylpoly-gamma-glutamate synthetase gene mRNA splice variants and protein expression in primary human leukemia cells, cell lines, and normal human tissues.
    Leclerc GJ; Barredo JC
    Clin Cancer Res; 2001 Apr; 7(4):942-51. PubMed ID: 11309345
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vitro uptake, anabolism, and cellular retention of 1843U89 and other benzoquinazoline inhibitors of thymidylate synthase.
    Hanlon MH; Ferone R
    Cancer Res; 1996 Jul; 56(14):3301-6. PubMed ID: 8764125
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of human liver folylpolyglutamate synthetase by non-gamma-glutamylatable antifolate analogs.
    Clarke L; Rosowsky A; Waxman DJ
    Mol Pharmacol; 1987 Jan; 31(1):122-7. PubMed ID: 3807889
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A strategy for the design of membrane-permeable folypoly-gamma-glutamate synthetase inhibitors: "bay-region"-substituted 2-desamino-2-methyl-5,8-dideazafolate analogs.
    Sanghani PC; Jackman A; Evans VR; Thornton T; Hughes L; Calvert AH; Moran RG
    Mol Pharmacol; 1994 Feb; 45(2):341-51. PubMed ID: 8114682
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human liver folylpolyglutamate synthetase: biochemical characterization and interactions with folates and folate antagonists.
    Clarke L; Waxman DJ
    Arch Biochem Biophys; 1987 Aug; 256(2):585-96. PubMed ID: 3619447
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Relevance of tumoral folylpolyglutamate synthetase and reduced folates for optimal 5-fluorouracil efficacy: experimental data.
    Chéradame S; Etienne MC; Chazal M; Guillot T; Fischel JL; Formento P; Milano G
    Eur J Cancer; 1997 May; 33(6):950-9. PubMed ID: 9291820
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Altered gene expression of folate enzymes in adjacent mucosa is associated with outcome of colorectal cancer patients.
    Odin E; Wettergren Y; Nilsson S; Willén R; Carlsson G; Spears CP; Larsson L; Gustavsson B
    Clin Cancer Res; 2003 Dec; 9(16 Pt 1):6012-9. PubMed ID: 14676127
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.