BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

133 related articles for article (PubMed ID: 8535396)

  • 1. Cytochrome P450 isozymes involved in aromatic hydroxylation and side-chain N-desisopropylation of alprenolol in rat liver microsomes.
    Narimatsu S; Tachibana M; Masubuchi Y; Imaoka S; Funae Y; Suzuki T
    Biol Pharm Bull; 1995 Aug; 18(8):1060-5. PubMed ID: 8535396
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regioselective contribution of the cytochrome P-450 2D subfamily to propranolol metabolism in rat liver microsomes.
    Masubuchi Y; Kagimoto N; Narimatsu S; Fujita S; Suzuki T
    Drug Metab Dispos; 1993; 21(6):1012-6. PubMed ID: 7905378
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cytochrome P450 isozymes catalyzing 4-hydroxylation of parkinsonism-related compound 1,2,3,4-tetrahydroisoquinoline in rat liver microsomes.
    Suzuki T; Fujita S; Narimatsu S; Masubuchi Y; Tachibana M; Ohta S; Hirobe M
    FASEB J; 1992 Jan; 6(2):771-6. PubMed ID: 1537468
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cytochrome P450 enzymes involved in the enhancement of propranolol N-desisopropylation after repeated administration of propranolol in rats.
    Narimatsu S; Mochida M; Matsumoto T; Masubuchi Y; Horie T; Nagata K; Funae Y; Cho AK; Suzuki T
    Chem Biol Interact; 1996 Sep; 101(3):207-24. PubMed ID: 8870689
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regioselectivity and substrate concentration-dependency of involvement of the CYP2D subfamily in oxidative metabolism of amitriptyline and nortriptyline in rat liver microsomes.
    Masubuchi Y; Iwasa T; Fujita S; Suzuki T; Horie T; Narimatsu S
    J Pharm Pharmacol; 1996 Sep; 48(9):925-9. PubMed ID: 9036183
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cytochrome P450 isozymes involved in propranolol metabolism in human liver microsomes. The role of CYP2D6 as ring-hydroxylase and CYP1A2 as N-desisopropylase.
    Masubuchi Y; Hosokawa S; Horie T; Suzuki T; Ohmori S; Kitada M; Narimatsu S
    Drug Metab Dispos; 1994; 22(6):909-15. PubMed ID: 7895609
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of human CYP isoforms involved in the metabolism of propranolol enantiomers--N-desisopropylation is mediated mainly by CYP1A2.
    Yoshimoto K; Echizen H; Chiba K; Tani M; Ishizaki T
    Br J Clin Pharmacol; 1995 Apr; 39(4):421-31. PubMed ID: 7640150
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An evaluation of cytochrome P450 isoform activities in the female dark agouti (DA) rat: relevance to its use as a model of the CYP2D6 poor metaboliser phenotype.
    Barham HM; Lennard MS; Tucker GT
    Biochem Pharmacol; 1994 Apr; 47(8):1295-307. PubMed ID: 8185638
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cytochrome P4502D isozymes catalyze the 4-hydroxylation of methamphetamine enantiomers.
    Lin LY; Kumagai Y; Hiratsuka A; Narimatsu S; Suzuki T; Funae Y; Distefano EW; Cho AK
    Drug Metab Dispos; 1995 Jun; 23(6):610-4. PubMed ID: 7587941
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Strain differences in CYP3A-mediated C-8 hydroxylation (1,3,7-trimethyluric acid formation) of caffeine in Wistar and Dark Agouti rats. Rapid metabolism of caffeine in debrisoquine poor metabolizer model rats.
    Morita K; Maeda Y; Masuda M; Kazusaka A; Imaoka S; Funae Y; Fujita S
    Biochem Pharmacol; 1998 May; 55(9):1405-11. PubMed ID: 10076532
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cytochrome P450-related differences between rats and mice in the metabolism of benzene, toluene and trichloroethylene in liver microsomes.
    Nakajima T; Wang RS; Elovaara E; Park SS; Gelboin HV; Vainio H
    Biochem Pharmacol; 1993 Mar; 45(5):1079-85. PubMed ID: 8461037
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Purification and characterization of a cytochrome P-450 isozyme catalyzing bunitrolol 4-hydroxylation in liver microsomes of male rats.
    Suzuki T; Narimatsu S; Fujita S; Masubuchi Y; Umeda S; Imaoka S; Funae Y
    Drug Metab Dispos; 1992; 20(3):367-73. PubMed ID: 1355709
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Participation of cytochrome P450-2B and -2D isozymes in the demethylenation of methylenedioxymethamphetamine enantiomers by rats.
    Kumagai Y; Lin LY; Hiratsuka A; Narimatsu S; Suzuki T; Yamada H; Oguri K; Yoshimura H; Cho AK
    Mol Pharmacol; 1994 Feb; 45(2):359-65. PubMed ID: 7906857
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Purification and characterization of a dog cytochrome P450 isozyme belonging to the CYP2D subfamily and development of its antipeptide antibody.
    Nakamura A; Yamamoto Y; Tasaki T; Sugimoto C; Masuda M; Kazusaka A; Fujita S
    Drug Metab Dispos; 1995 Nov; 23(11):1268-73. PubMed ID: 8591729
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cytochrome P4502D and -2C enzymes catalyze the oxidative N-demethylation of the parkinsonism-inducing substance 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in rat liver microsomes.
    Narimatsu S; Tachibana M; Masubuchi Y; Suzuki T
    Chem Res Toxicol; 1996; 9(1):93-8. PubMed ID: 8924622
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tissue, species, and substrate concentration differences in the position-selective hydroxylation of N-nitrosodibutylamine. Relationship to the distribution of cytochrome P-450 isozymes 2 (IIB) and 5 (IVB).
    Schulze J; Richter E; Philpot RM
    Drug Metab Dispos; 1990; 18(4):398-402. PubMed ID: 1976059
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Oxidation of R(+)- and S(-)-carvedilol by rat liver microsomes. Evidence for stereoselective oxidation and characterization of the cytochrome P450 isozymes involved.
    Fujimaki M
    Drug Metab Dispos; 1994; 22(5):700-8. PubMed ID: 7835220
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential roles of cytochromes P450 2D1, 2C11, and 1A1/2 in the hydroxylation of bufuralol by rat liver microsomes.
    Mimura M; Yamazaki H; Sugahara C; Hiroi T; Funae Y; Shimada T
    Biochem Pharmacol; 1994 Jun; 47(11):1957-63. PubMed ID: 7912070
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Species difference in enantioselectivity for the oxidation of propranolol by cytochrome P450 2D enzymes.
    Narimatsu S; Kobayashi N; Masubuchi Y; Horie T; Kakegawa T; Kobayashi H; Hardwick JP; Gonzalez FJ; Shimada N; Ohmori S; Kitada M; Asaoka K; Kataoka H; Yamamoto S; Satoh T
    Chem Biol Interact; 2000 Jun; 127(1):73-90. PubMed ID: 10903420
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Kinetic studies of dose-dependent metabolism of alprenolol: in vitro and in vivo studies in different species.
    Skånberg I; Borg KO; Fellenius E; Hoffmann KJ; von Bahr C; Moldéus P
    Acta Pharmacol Toxicol (Copenh); 1979 Jan; 44(1):28-35. PubMed ID: 760385
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.