BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

166 related articles for article (PubMed ID: 8537389)

  • 1. A novel kinetic analysis to calculate nucleotide affinity of proofreading DNA polymerases. Application to phi 29 DNA polymerase fidelity mutants.
    Saturno J; Blanco L; Salas M; Esteban JA
    J Biol Chem; 1995 Dec; 270(52):31235-43. PubMed ID: 8537389
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phi 29 DNA polymerase active site. Mutants in conserved residues Tyr254 and Tyr390 are affected in dNTP binding.
    Blasco MA; Lázaro JM; Bernad A; Blanco L; Salas M
    J Biol Chem; 1992 Sep; 267(27):19427-34. PubMed ID: 1527062
    [TBL] [Abstract][Full Text] [Related]  

  • 3. phi 29 DNA polymerase residue Leu384, highly conserved in motif B of eukaryotic type DNA replicases, is involved in nucleotide insertion fidelity.
    Truniger V; Lázaro JM; de Vega M; Blanco L; Salas M
    J Biol Chem; 2003 Aug; 278(35):33482-91. PubMed ID: 12805385
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Two positively charged residues of phi29 DNA polymerase, conserved in protein-primed DNA polymerases, are involved in stabilisation of the incoming nucleotide.
    Truniger V; Lázaro JM; Salas M
    J Mol Biol; 2004 Jan; 335(2):481-94. PubMed ID: 14672657
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Fidelity of phi 29 DNA polymerase. Comparison between protein-primed initiation and DNA polymerization.
    Esteban JA; Salas M; Blanco L
    J Biol Chem; 1993 Feb; 268(4):2719-26. PubMed ID: 8428945
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pre-steady-state Kinetic Analysis of a Family D DNA Polymerase from Thermococcus sp. 9°N Reveals Mechanisms for Archaeal Genomic Replication and Maintenance.
    Schermerhorn KM; Gardner AF
    J Biol Chem; 2015 Sep; 290(36):21800-10. PubMed ID: 26160179
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Primer-terminus stabilization at the 3'-5' exonuclease active site of phi29 DNA polymerase. Involvement of two amino acid residues highly conserved in proofreading DNA polymerases.
    de Vega M; Lazaro JM; Salas M; Blanco L
    EMBO J; 1996 Mar; 15(5):1182-92. PubMed ID: 8605889
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phi 29 DNA polymerase active site. The conserved amino acid motif "Kx3NSxYG" is involved in template-primer binding and dNTP selection.
    Blasco MA; Lázaro JM; Blanco L; Salas M
    J Biol Chem; 1993 Aug; 268(22):16763-70. PubMed ID: 8344956
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A highly conserved lysine residue in phi29 DNA polymerase is important for correct binding of the templating nucleotide during initiation of phi29 DNA replication.
    Truniger V; Lázaro JM; Blanco L; Salas M
    J Mol Biol; 2002 Apr; 318(1):83-96. PubMed ID: 12054770
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Primer terminus stabilization at the phi 29 DNA polymerase active site. Mutational analysis of conserved motif KXY.
    Blasco MA; Méndez J; Lázaro JM; Blanco L; Salas M
    J Biol Chem; 1995 Feb; 270(6):2735-40. PubMed ID: 7852344
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural and functional studies on phi 29 DNA polymerase.
    Blasco MA; Esteban JA; Méndez J; Blanco L; Salas M
    Chromosoma; 1992; 102(1 Suppl):S32-8. PubMed ID: 1291240
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ø29 DNA polymerase residue Lys383, invariant at motif B of DNA-dependent polymerases, is involved in dNTP binding.
    Saturno J; Lázaro JM; Esteban FJ; Blanco L; Salas M
    J Mol Biol; 1997 Jun; 269(3):313-25. PubMed ID: 9199402
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dynamics of translocation and substrate binding in individual complexes formed with active site mutants of {phi}29 DNA polymerase.
    Dahl JM; Wang H; Lázaro JM; Salas M; Lieberman KR
    J Biol Chem; 2014 Mar; 289(10):6350-6361. PubMed ID: 24464581
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutants affecting nucleotide recognition by T7 DNA polymerase.
    Donlin MJ; Johnson KA
    Biochemistry; 1994 Dec; 33(49):14908-17. PubMed ID: 7993917
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Noncatalytic aspartate at the exonuclease domain of proofreading DNA polymerases regulates both degradative and synthetic activities.
    Del Prado A; Franco-Echevarría E; González B; Blanco L; Salas M; de Vega M
    Proc Natl Acad Sci U S A; 2018 Mar; 115(13):E2921-E2929. PubMed ID: 29531047
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of the LEXE motif of protein-primed DNA polymerases in the interaction with the incoming nucleotide.
    Santos E; Lázaro JM; Pérez-Arnaiz P; Salas M; de Vega M
    J Biol Chem; 2014 Jan; 289(5):2888-98. PubMed ID: 24324256
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A highly conserved Tyrosine residue of family B DNA polymerases contributes to dictate translesion synthesis past 8-oxo-7,8-dihydro-2'-deoxyguanosine.
    de Vega M; Salas M
    Nucleic Acids Res; 2007; 35(15):5096-107. PubMed ID: 17652324
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A positively charged residue of phi29 DNA polymerase, highly conserved in DNA polymerases from families A and B, is involved in binding the incoming nucleotide.
    Truniger V; Lázaro JM; Esteban FJ; Blanco L; Salas M
    Nucleic Acids Res; 2002 Apr; 30(7):1483-92. PubMed ID: 11917008
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The fidelity of DNA synthesis catalyzed by derivatives of Escherichia coli DNA polymerase I.
    Bebenek K; Joyce CM; Fitzgerald MP; Kunkel TA
    J Biol Chem; 1990 Aug; 265(23):13878-87. PubMed ID: 2199444
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutational studies of human DNA polymerase alpha. Identification of residues critical for deoxynucleotide binding and misinsertion fidelity of DNA synthesis.
    Dong Q; Copeland WC; Wang TS
    J Biol Chem; 1993 Nov; 268(32):24163-74. PubMed ID: 8226963
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.