These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 8542574)

  • 1. The phosphatidylinositol 3-kinase inhibitor wortmannin sensitizes murine fibroblasts and human tumor cells to radiation and blocks induction of p53 following DNA damage.
    Price BD; Youmell MB
    Cancer Res; 1996 Jan; 56(2):246-50. PubMed ID: 8542574
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of the protein kinase inhibitors wortmannin and KN62 on cellular radiosensitivity and radiation-activated S phase and G1/S checkpoints in normal human fibroblasts.
    Enns L; Murray D; Mirzayans R
    Br J Cancer; 1999 Nov; 81(6):959-65. PubMed ID: 10576651
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Low dose of wortmannin reduces radiosensitivity of human glioblastoma cells through the p53 pathway.
    Okaichi K; Suzuki K; Morita N; Ikeda M; Takahashi H; Matsuda N; Watanabe M; Okumura Y
    Oncol Rep; 2002; 9(4):859-62. PubMed ID: 12066222
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Relationship between the radiosensitizing effect of wortmannin, DNA double-strand break rejoining, and p21WAF1 induction in human normal and tumor-derived cells.
    Mirzayans R; Pollock S; Scott A; Enns L; Andrais B; Murray D
    Mol Carcinog; 2004 Mar; 39(3):164-72. PubMed ID: 14991746
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Wortmannin, a specific phosphatidylinositol 3-kinase inhibitor, inhibits adipocytic differentiation of 3T3-L1 cells.
    Tomiyama K; Nakata H; Sasa H; Arimura S; Nishio E; Watanabe Y
    Biochem Biophys Res Commun; 1995 Jul; 212(1):263-9. PubMed ID: 7541986
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphatidylinositol 3-kinase inhibitor wortmannin blocks mitogenic activation of the transferrin receptor gene promoter in late G1.
    Miskimins WK; King F; Miskimins R
    Cell Growth Differ; 1997 May; 8(5):565-70. PubMed ID: 9149907
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase.
    Powis G; Bonjouklian R; Berggren MM; Gallegos A; Abraham R; Ashendel C; Zalkow L; Matter WF; Dodge J; Grindey G
    Cancer Res; 1994 May; 54(9):2419-23. PubMed ID: 8162590
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Wortmannin sensitizes mammalian cells to radiation by inhibiting the DNA-dependent protein kinase-mediated rejoining of double-strand breaks.
    Chernikova SB; Wells RL; Elkind MM
    Radiat Res; 1999 Feb; 151(2):159-66. PubMed ID: 9952300
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Radiosensitization of human tumor cells by the phosphatidylinositol3-kinase inhibitors wortmannin and LY294002 correlates with inhibition of DNA-dependent protein kinase and prolonged G2-M delay.
    Rosenzweig KE; Youmell MB; Palayoor ST; Price BD
    Clin Cancer Res; 1997 Jul; 3(7):1149-56. PubMed ID: 9815794
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin.
    Sarkaria JN; Tibbetts RS; Busby EC; Kennedy AP; Hill DE; Abraham RT
    Cancer Res; 1998 Oct; 58(19):4375-82. PubMed ID: 9766667
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Studies on the mechanism of phosphatidylinositol 3-kinase inhibition by wortmannin and related analogs.
    Norman BH; Shih C; Toth JE; Ray JE; Dodge JA; Johnson DW; Rutherford PG; Schultz RM; Worzalla JF; Vlahos CJ
    J Med Chem; 1996 Mar; 39(5):1106-11. PubMed ID: 8676346
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of hyperthermia on p53 protein expression and activity.
    Guan J; Stavridi E; Leeper DB; Iliakis G
    J Cell Physiol; 2002 Mar; 190(3):365-74. PubMed ID: 11857452
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Growth factor-dependent survival of rodent fibroblasts requires phosphatidylinositol 3-kinase but is independent of pp70S6K activity.
    Yao R; Cooper GM
    Oncogene; 1996 Jul; 13(2):343-51. PubMed ID: 8710373
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Wortmannin, a phosphoinositide 3-kinase inhibitor, selectively enhances cytotoxicity of receptor-directed-toxin chimeras in vitro and in vivo.
    Davol PA; Bizuneh A; Frackelton AR
    Anticancer Res; 1999; 19(3A):1705-13. PubMed ID: 10470104
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vitro and in vivo antitumor activity of the phosphatidylinositol-3-kinase inhibitor, wortmannin.
    Schultz RM; Merriman RL; Andis SL; Bonjouklian R; Grindey GB; Rutherford PG; Gallegos A; Massey K; Powis G
    Anticancer Res; 1995; 15(4):1135-9. PubMed ID: 7653991
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Paclitaxel enhanced radiation sensitization for the suppression of human prostate cancer tumor growth via a p53 independent pathway.
    Zhang AL; Russell PJ; Knittel T; Milross C
    Prostate; 2007 Nov; 67(15):1630-40. PubMed ID: 17823933
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of base excision repair potentiates iododeoxyuridine-induced cytotoxicity and radiosensitization.
    Taverna P; Hwang HS; Schupp JE; Radivoyevitch T; Session NN; Reddy G; Zarling DA; Kinsella TJ
    Cancer Res; 2003 Feb; 63(4):838-46. PubMed ID: 12591735
    [TBL] [Abstract][Full Text] [Related]  

  • 18. p53 is involved in regulation of the DNA repair gene O6-methylguanine-DNA methyltransferase (MGMT) by DNA damaging agents.
    Grombacher T; Eichhorn U; Kaina B
    Oncogene; 1998 Aug; 17(7):845-51. PubMed ID: 9780001
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Growth-inhibitory effect of phosphatidylinositol 3-kinase inhibitor on human pancreatic cancer cells and expression of Bcl-2 family.
    Katayose K; Seki T; Ohba N; Funatomi H; Goto N; Mitamura K
    Anticancer Res; 2003; 23(3B):2383-7. PubMed ID: 12894518
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of p53 status and wortmannin treatment on potentially lethal damage repair, with emphasis on the response of intratumor quiescent cells.
    Masunaga S; Takahashi A; Ohnishi K; Ohnishi T; Suzuki M; Nagata K; Kinashi Y; Ono K
    Radiat Med; 2003; 21(3):120-7. PubMed ID: 12868860
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.