These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

81 related articles for article (PubMed ID: 8547241)

  • 1. HIV-1 reverse transcriptase resistance to nonnucleoside inhibitors.
    Spence RA; Anderson KS; Johnson KA
    Biochemistry; 1996 Jan; 35(3):1054-63. PubMed ID: 8547241
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanism of inhibition of HIV-1 reverse transcriptase by nonnucleoside inhibitors.
    Spence RA; Kati WM; Anderson KS; Johnson KA
    Science; 1995 Feb; 267(5200):988-93. PubMed ID: 7532321
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differences in the inhibition of human immunodeficiency virus type 1 reverse transcriptase DNA polymerase activity by analogs of nevirapine and [2',5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro-5"-(4"-amino-1", 2"-oxathiole-2",2"-dioxide] (TSAO).
    Arion D; Fletcher RS; Borkow G; Camarasa MJ; Balzarini J; Dmitrienko GI; Parniak MA
    Mol Pharmacol; 1996 Nov; 50(5):1057-64. PubMed ID: 8913335
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bridge water mediates nevirapine binding to wild type and Y181C HIV-1 reverse transcriptase--evidence from molecular dynamics simulations and MM-PBSA calculations.
    Treesuwan W; Hannongbua S
    J Mol Graph Model; 2009; 27(8):921-9. PubMed ID: 19414275
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Enzymatic properties of two mutants of reverse transcriptase of human immunodeficiency virus type 1 (tyrosine 181-->isoleucine and tyrosine 188-->leucine), resistant to nonnucleoside inhibitors.
    Loya S; Bakhanashvili M; Tal R; Hughes SH; Boyer PL; Hizi A
    AIDS Res Hum Retroviruses; 1994 Aug; 10(8):939-46. PubMed ID: 7529032
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure of HIV-1 RT/TIBO R 86183 complex reveals similarity in the binding of diverse nonnucleoside inhibitors.
    Ding J; Das K; Moereels H; Koymans L; Andries K; Janssen PA; Hughes SH; Arnold E
    Nat Struct Biol; 1995 May; 2(5):407-15. PubMed ID: 7545077
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular modeling studies of HIV-1 reverse transcriptase nonnucleoside inhibitors: total energy of complexation as a predictor of drug placement and activity.
    Kroeger Smith MB; Rouzer CA; Taneyhill LA; Smith NA; Hughes SH; Boyer PL; Janssen PA; Moereels H; Koymans L; Arnold E
    Protein Sci; 1995 Oct; 4(10):2203-22. PubMed ID: 8535257
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel nonnucleoside inhibitors of HIV-1 reverse transcriptase. 7. 8-Arylethyldipyridodiazepinones as potent broad-spectrum inhibitors of wild-type and mutant enzymes.
    Klunder JM; Hoermann M; Cywin CL; David E; Brickwood JR; Schwartz R; Barringer KJ; Pauletti D; Shih CK; Erickson DA; Sorge CL; Joseph DP; Hattox SE; Adams J; Grob PM
    J Med Chem; 1998 Jul; 41(16):2960-71. PubMed ID: 9685235
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pre-steady-state kinetic characterization of wild type and 3'-azido-3'-deoxythymidine (AZT) resistant human immunodeficiency virus type 1 reverse transcriptase: implication of RNA directed DNA polymerization in the mechanism of AZT resistance.
    Kerr SG; Anderson KS
    Biochemistry; 1997 Nov; 36(46):14064-70. PubMed ID: 9369478
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Resistance to nevirapine of HIV-1 reverse transcriptase mutants: loss of stabilizing interactions and thermodynamic or steric barriers are induced by different single amino acid substitutions.
    Maga G; Amacker M; Ruel N; Hübscher U; Spadari S
    J Mol Biol; 1997 Dec; 274(5):738-47. PubMed ID: 9405155
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Resistance to 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives is generated by mutations at multiple sites in the HIV-1 reverse transcriptase.
    Buckheit RW; Fliakas-Boltz V; Yeagy-Bargo S; Weislow O; Mayers DL; Boyer PL; Hughes SH; Pan BC; Chu SH; Bader JP
    Virology; 1995 Jun; 210(1):186-93. PubMed ID: 7540784
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Y181C mutant of HIV-1 reverse transcriptase resistant to nonnucleoside reverse transcriptase inhibitors alters the size distribution of RNase H cleavages.
    Archer RH; Wisniewski M; Bambara RA; Demeter LM
    Biochemistry; 2001 Apr; 40(13):4087-95. PubMed ID: 11300789
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel mechanism of inhibition of HIV-1 reverse transcriptase by a new non-nucleoside analog, KM-1.
    Wang LZ; Kenyon GL; Johnson KA
    J Biol Chem; 2004 Sep; 279(37):38424-32. PubMed ID: 15231830
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Investigating the mutation resistance of nonnucleoside inhibitors of HIV-RT using multiple microsecond atomistic simulations.
    Monroe JI; El-Nahal WG; Shirts MR
    Proteins; 2014 Jan; 82(1):130-44. PubMed ID: 23775803
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design of nevirapine derivatives insensitive to the K103N and Y181C HIV-1 reverse transcriptase mutants.
    Saparpakorn P; Hannongbua S; Rognan D
    SAR QSAR Environ Res; 2006 Apr; 17(2):183-94. PubMed ID: 16644557
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human immunodeficiency virus reverse transcriptase substrate-induced conformational changes and the mechanism of inhibition by nonnucleoside inhibitors.
    Rittinger K; Divita G; Goody RS
    Proc Natl Acad Sci U S A; 1995 Aug; 92(17):8046-9. PubMed ID: 7544013
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure of HIV-1 reverse transcriptase in a complex with the non-nucleoside inhibitor alpha-APA R 95845 at 2.8 A resolution.
    Ding J; Das K; Tantillo C; Zhang W; Clark AD; Jessen S; Lu X; Hsiou Y; Jacobo-Molina A; Andries K
    Structure; 1995 Apr; 3(4):365-79. PubMed ID: 7542140
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sensitivity and resistance to (+)-calanolide A of wild-type and mutated forms of HIV-1 reverse transcriptase.
    Quan Y; Motakis D; Buckheit R; Xu ZQ; Flavin MT; Parniak MA; Wainberg MA
    Antivir Ther; 1999; 4(4):203-9. PubMed ID: 10723499
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Probing nonnucleoside inhibitor-induced active-site distortion in HIV-1 reverse transcriptase by transient kinetic analyses.
    Xia Q; Radzio J; Anderson KS; Sluis-Cremer N
    Protein Sci; 2007 Aug; 16(8):1728-37. PubMed ID: 17656585
    [TBL] [Abstract][Full Text] [Related]  

  • 20. High resolution structures of HIV-1 RT from four RT-inhibitor complexes.
    Ren J; Esnouf R; Garman E; Somers D; Ross C; Kirby I; Keeling J; Darby G; Jones Y; Stuart D
    Nat Struct Biol; 1995 Apr; 2(4):293-302. PubMed ID: 7540934
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.