These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

133 related articles for article (PubMed ID: 8552391)

  • 1. DNA-binding by oncoprotein E2a-Pbx1 is important for blocking differentiation but dispensable for fibroblast transformation.
    Kamps MP; Wright DD; Lu Q
    Oncogene; 1996 Jan; 12(1):19-30. PubMed ID: 8552391
    [TBL] [Abstract][Full Text] [Related]  

  • 2. An inhibitory switch derepressed by pbx, hox, and Meis/Prep1 partners regulates DNA-binding by pbx1 and E2a-pbx1 and is dispensable for myeloid immortalization by E2a-pbx1.
    Calvo KR; Knoepfler P; McGrath S; Kamps MP
    Oncogene; 1999 Dec; 18(56):8033-43. PubMed ID: 10637514
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Oncoprotein E2A-Pbx1 immortalizes a myeloid progenitor in primary marrow cultures without abrogating its factor-dependence.
    Kamps MP; Wright DD
    Oncogene; 1994 Nov; 9(11):3159-66. PubMed ID: 7936638
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Critical role for a single leucine residue in leukemia induction by E2A-PBX1.
    Bayly R; Murase T; Hyndman BD; Savage R; Nurmohamed S; Munro K; Casselman R; Smith SP; LeBrun DP
    Mol Cell Biol; 2006 Sep; 26(17):6442-52. PubMed ID: 16914730
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Fusion with E2A alters the transcriptional properties of the homeodomain protein PBX1 in t(1;19) leukemias.
    LeBrun DP; Cleary ML
    Oncogene; 1994 Jun; 9(6):1641-7. PubMed ID: 8183558
    [TBL] [Abstract][Full Text] [Related]  

  • 6. EB-1, a tyrosine kinase signal transduction gene, is transcriptionally activated in the t(1;19) subset of pre-B ALL, which express oncoprotein E2a-Pbx1.
    Fu X; McGrath S; Pasillas M; Nakazawa S; Kamps MP
    Oncogene; 1999 Sep; 18(35):4920-9. PubMed ID: 10490826
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transformation properties of the E2a-Pbx1 chimeric oncoprotein: fusion with E2a is essential, but the Pbx1 homeodomain is dispensable.
    Monica K; LeBrun DP; Dedera DA; Brown R; Cleary ML
    Mol Cell Biol; 1994 Dec; 14(12):8304-14. PubMed ID: 7969166
    [TBL] [Abstract][Full Text] [Related]  

  • 8. E2a/Pbx1 oncogene inhibits terminal differentiation but not myeloid potential of pro-T cells.
    Bourette RP; Grasset MF; Mouchiroud G
    Oncogene; 2007 Jan; 26(2):234-47. PubMed ID: 16819510
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The highest affinity DNA element bound by Pbx complexes in t(1;19) leukemic cells fails to mediate cooperative DNA-binding or cooperative transactivation by E2a-Pbx1 and class I Hox proteins - evidence for selective targetting of E2a-Pbx1 to a subset of Pbx-recognition elements.
    Knoepfler PS; Kamps MP
    Oncogene; 1997 May; 14(21):2521-31. PubMed ID: 9191052
    [TBL] [Abstract][Full Text] [Related]  

  • 10. HoxB8 requires its Pbx-interaction motif to block differentiation of primary myeloid progenitors and of most cell line models of myeloid differentiation.
    Knoepfler PS; Sykes DB; Pasillas M; Kamps MP
    Oncogene; 2001 Sep; 20(39):5440-8. PubMed ID: 11571641
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chimeric oncoprotein E2a-Pbx1 induces apoptosis of hematopoietic cells by a p53-independent mechanism that is suppressed by Bcl-2.
    Smith KS; Jacobs Y; Chang CP; Cleary ML
    Oncogene; 1997 Jun; 14(24):2917-26. PubMed ID: 9205098
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Heterodimerization of Hox proteins with Pbx1 and oncoprotein E2a-Pbx1 generates unique DNA-binding specifities at nucleotides predicted to contact the N-terminal arm of the Hox homeodomain--demonstration of Hox-dependent targeting of E2a-Pbx1 in vivo.
    Lu Q; Kamps MP
    Oncogene; 1997 Jan; 14(1):75-83. PubMed ID: 9010234
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The chimeric oncoproteins E2A-PBX1 and E2A-HLF are concentrated within spherical nuclear domains.
    LeBrun DP; Matthews BP; Feldman BJ; Cleary ML
    Oncogene; 1997 Oct; 15(17):2059-67. PubMed ID: 9366523
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation.
    Lu Q; Wright DD; Kamps MP
    Mol Cell Biol; 1994 Jun; 14(6):3938-48. PubMed ID: 7910944
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Hox cooperativity motif of the chimeric oncoprotein E2a-Pbx1 is necessary and sufficient for oncogenesis.
    Chang CP; de Vivo I; Cleary ML
    Mol Cell Biol; 1997 Jan; 17(1):81-8. PubMed ID: 8972188
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes.
    Lu Q; Knoepfler PS; Scheele J; Wright DD; Kamps MP
    Mol Cell Biol; 1995 Jul; 15(7):3786-95. PubMed ID: 7791786
    [TBL] [Abstract][Full Text] [Related]  

  • 17. E2a-Pbx1 induces aberrant expression of tissue-specific and developmentally regulated genes when expressed in NIH 3T3 fibroblasts.
    Fu X; Kamps MP
    Mol Cell Biol; 1997 Mar; 17(3):1503-12. PubMed ID: 9032278
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Spt-Ada-Gcn5-acetyltransferase complex interaction motif of E2a is essential for a subset of transcriptional and oncogenic properties of E2a-Pbx1.
    Scheele JS; Kolanczyk M; Gantert M; Zemojtel T; Dorn A; Sykes DB; Möbest DC; Kamps MP; Räpple D
    Leuk Lymphoma; 2009 May; 50(5):816-28. PubMed ID: 19399691
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The human t(1;19) translocation in pre-B ALL produces multiple nuclear E2A-Pbx1 fusion proteins with differing transforming potentials.
    Kamps MP; Look AT; Baltimore D
    Genes Dev; 1991 Mar; 5(3):358-68. PubMed ID: 1672117
    [TBL] [Abstract][Full Text] [Related]  

  • 20. AML-2 is a potential target for transcriptional regulation by the t(8;21) and t(12;21) fusion proteins in acute leukemia.
    Meyers S; Lenny N; Sun W; Hiebert SW
    Oncogene; 1996 Jul; 13(2):303-12. PubMed ID: 8710369
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.