136 related articles for article (PubMed ID: 8552391)
1. DNA-binding by oncoprotein E2a-Pbx1 is important for blocking differentiation but dispensable for fibroblast transformation.
Kamps MP; Wright DD; Lu Q
Oncogene; 1996 Jan; 12(1):19-30. PubMed ID: 8552391
[TBL] [Abstract][Full Text] [Related]
2. An inhibitory switch derepressed by pbx, hox, and Meis/Prep1 partners regulates DNA-binding by pbx1 and E2a-pbx1 and is dispensable for myeloid immortalization by E2a-pbx1.
Calvo KR; Knoepfler P; McGrath S; Kamps MP
Oncogene; 1999 Dec; 18(56):8033-43. PubMed ID: 10637514
[TBL] [Abstract][Full Text] [Related]
3. Oncoprotein E2A-Pbx1 immortalizes a myeloid progenitor in primary marrow cultures without abrogating its factor-dependence.
Kamps MP; Wright DD
Oncogene; 1994 Nov; 9(11):3159-66. PubMed ID: 7936638
[TBL] [Abstract][Full Text] [Related]
4. Critical role for a single leucine residue in leukemia induction by E2A-PBX1.
Bayly R; Murase T; Hyndman BD; Savage R; Nurmohamed S; Munro K; Casselman R; Smith SP; LeBrun DP
Mol Cell Biol; 2006 Sep; 26(17):6442-52. PubMed ID: 16914730
[TBL] [Abstract][Full Text] [Related]
5. Fusion with E2A alters the transcriptional properties of the homeodomain protein PBX1 in t(1;19) leukemias.
LeBrun DP; Cleary ML
Oncogene; 1994 Jun; 9(6):1641-7. PubMed ID: 8183558
[TBL] [Abstract][Full Text] [Related]
6. EB-1, a tyrosine kinase signal transduction gene, is transcriptionally activated in the t(1;19) subset of pre-B ALL, which express oncoprotein E2a-Pbx1.
Fu X; McGrath S; Pasillas M; Nakazawa S; Kamps MP
Oncogene; 1999 Sep; 18(35):4920-9. PubMed ID: 10490826
[TBL] [Abstract][Full Text] [Related]
7. Transformation properties of the E2a-Pbx1 chimeric oncoprotein: fusion with E2a is essential, but the Pbx1 homeodomain is dispensable.
Monica K; LeBrun DP; Dedera DA; Brown R; Cleary ML
Mol Cell Biol; 1994 Dec; 14(12):8304-14. PubMed ID: 7969166
[TBL] [Abstract][Full Text] [Related]
8. E2a/Pbx1 oncogene inhibits terminal differentiation but not myeloid potential of pro-T cells.
Bourette RP; Grasset MF; Mouchiroud G
Oncogene; 2007 Jan; 26(2):234-47. PubMed ID: 16819510
[TBL] [Abstract][Full Text] [Related]
9. The highest affinity DNA element bound by Pbx complexes in t(1;19) leukemic cells fails to mediate cooperative DNA-binding or cooperative transactivation by E2a-Pbx1 and class I Hox proteins - evidence for selective targetting of E2a-Pbx1 to a subset of Pbx-recognition elements.
Knoepfler PS; Kamps MP
Oncogene; 1997 May; 14(21):2521-31. PubMed ID: 9191052
[TBL] [Abstract][Full Text] [Related]
10. HoxB8 requires its Pbx-interaction motif to block differentiation of primary myeloid progenitors and of most cell line models of myeloid differentiation.
Knoepfler PS; Sykes DB; Pasillas M; Kamps MP
Oncogene; 2001 Sep; 20(39):5440-8. PubMed ID: 11571641
[TBL] [Abstract][Full Text] [Related]
11. Chimeric oncoprotein E2a-Pbx1 induces apoptosis of hematopoietic cells by a p53-independent mechanism that is suppressed by Bcl-2.
Smith KS; Jacobs Y; Chang CP; Cleary ML
Oncogene; 1997 Jun; 14(24):2917-26. PubMed ID: 9205098
[TBL] [Abstract][Full Text] [Related]
12. Heterodimerization of Hox proteins with Pbx1 and oncoprotein E2a-Pbx1 generates unique DNA-binding specifities at nucleotides predicted to contact the N-terminal arm of the Hox homeodomain--demonstration of Hox-dependent targeting of E2a-Pbx1 in vivo.
Lu Q; Kamps MP
Oncogene; 1997 Jan; 14(1):75-83. PubMed ID: 9010234
[TBL] [Abstract][Full Text] [Related]
13. The chimeric oncoproteins E2A-PBX1 and E2A-HLF are concentrated within spherical nuclear domains.
LeBrun DP; Matthews BP; Feldman BJ; Cleary ML
Oncogene; 1997 Oct; 15(17):2059-67. PubMed ID: 9366523
[TBL] [Abstract][Full Text] [Related]
14. Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation.
Lu Q; Wright DD; Kamps MP
Mol Cell Biol; 1994 Jun; 14(6):3938-48. PubMed ID: 7910944
[TBL] [Abstract][Full Text] [Related]
15. The Hox cooperativity motif of the chimeric oncoprotein E2a-Pbx1 is necessary and sufficient for oncogenesis.
Chang CP; de Vivo I; Cleary ML
Mol Cell Biol; 1997 Jan; 17(1):81-8. PubMed ID: 8972188
[TBL] [Abstract][Full Text] [Related]
16. Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes.
Lu Q; Knoepfler PS; Scheele J; Wright DD; Kamps MP
Mol Cell Biol; 1995 Jul; 15(7):3786-95. PubMed ID: 7791786
[TBL] [Abstract][Full Text] [Related]
17. E2a-Pbx1 induces aberrant expression of tissue-specific and developmentally regulated genes when expressed in NIH 3T3 fibroblasts.
Fu X; Kamps MP
Mol Cell Biol; 1997 Mar; 17(3):1503-12. PubMed ID: 9032278
[TBL] [Abstract][Full Text] [Related]
18. The Spt-Ada-Gcn5-acetyltransferase complex interaction motif of E2a is essential for a subset of transcriptional and oncogenic properties of E2a-Pbx1.
Scheele JS; Kolanczyk M; Gantert M; Zemojtel T; Dorn A; Sykes DB; Möbest DC; Kamps MP; Räpple D
Leuk Lymphoma; 2009 May; 50(5):816-28. PubMed ID: 19399691
[TBL] [Abstract][Full Text] [Related]
19. The human t(1;19) translocation in pre-B ALL produces multiple nuclear E2A-Pbx1 fusion proteins with differing transforming potentials.
Kamps MP; Look AT; Baltimore D
Genes Dev; 1991 Mar; 5(3):358-68. PubMed ID: 1672117
[TBL] [Abstract][Full Text] [Related]
20. AML-2 is a potential target for transcriptional regulation by the t(8;21) and t(12;21) fusion proteins in acute leukemia.
Meyers S; Lenny N; Sun W; Hiebert SW
Oncogene; 1996 Jul; 13(2):303-12. PubMed ID: 8710369
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
