These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

798 related articles for article (PubMed ID: 8553070)

  • 1. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1.
    Hahn SA; Schutte M; Hoque AT; Moskaluk CA; da Costa LT; Rozenblum E; Weinstein CL; Fischer A; Yeo CJ; Hruban RH; Kern SE
    Science; 1996 Jan; 271(5247):350-3. PubMed ID: 8553070
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The 18q21 region in colorectal and pancreatic cancer: independent loss of DCC and DPC4 expression.
    Barberá VM; Martín M; Mariñoso L; Munné A; Carrato A; Real FX; Fabre M
    Biochim Biophys Acta; 2000 Oct; 1502(2):283-96. PubMed ID: 11040453
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Homozygous deletions inactivate DCC, but not MADH4/DPC4/SMAD4, in a subset of pancreatic and biliary cancers.
    Hilgers W; Song JJ; Haye M; Hruban RR; Kern SE; Fearon ER
    Genes Chromosomes Cancer; 2000 Apr; 27(4):353-7. PubMed ID: 10719364
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inactivation of both alleles of the DPC4/SMAD4 gene in advanced colorectal cancers: identification of seven novel somatic mutations in tumors from Japanese patients.
    Koyama M; Ito M; Nagai H; Emi M; Moriyama Y
    Mutat Res; 1999 Aug; 406(2-4):71-7. PubMed ID: 10479724
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DPC4 gene in various tumor types.
    Schutte M; Hruban RH; Hedrick L; Cho KR; Nadasdy GM; Weinstein CL; Bova GS; Isaacs WB; Cairns P; Nawroz H; Sidransky D; Casero RA; Meltzer PS; Hahn SA; Kern SE
    Cancer Res; 1996 Jun; 56(11):2527-30. PubMed ID: 8653691
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers.
    Thiagalingam S; Lengauer C; Leach FS; Schutte M; Hahn SA; Overhauser J; Willson JK; Markowitz S; Hamilton SR; Kern SE; Kinzler KW; Vogelstein B
    Nat Genet; 1996 Jul; 13(3):343-6. PubMed ID: 8673134
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expression and mutational analysis of the DCC, DPC4, and MADR2/JV18-1 genes in neuroblastoma.
    Kong XT; Choi SH; Inoue A; Xu F; Chen T; Takita J; Yokota J; Bessho F; Yanagisawa M; Hanada R; Yamamoto K; Hayashi Y
    Cancer Res; 1997 Sep; 57(17):3772-8. PubMed ID: 9288786
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Comparative mutational analysis of DPC4 (Smad4) in prostatic and colorectal carcinomas.
    MacGrogan D; Pegram M; Slamon D; Bookstein R
    Oncogene; 1997 Aug; 15(9):1111-4. PubMed ID: 9285566
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DPC4 (SMAD4) mediates transforming growth factor-beta1 (TGF-beta1) induced growth inhibition and transcriptional response in breast tumour cells.
    de Winter JP; Roelen BA; ten Dijke P; van der Burg B; van den Eijnden-van Raaij AJ
    Oncogene; 1997 Apr; 14(16):1891-9. PubMed ID: 9150356
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Analysis of the DPC4 gene in gastric carcinoma.
    Nishizuka S; Tamura G; Maesawa C; Sakata K; Suzuki Y; Iwaya T; Terashima M; Saito K; Satodate R
    Jpn J Cancer Res; 1997 Apr; 88(4):335-9. PubMed ID: 9197522
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Induction of p21waf1 expression and growth inhibition by transforming growth factor beta involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells.
    Grau AM; Zhang L; Wang W; Ruan S; Evans DB; Abbruzzese JL; Zhang W; Chiao PJ
    Cancer Res; 1997 Sep; 57(18):3929-34. PubMed ID: 9307274
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mapping of a breast cancer tumor suppressor gene locus to a 4-cM interval on chromosome 18q21.
    Yokota T; Matsumoto S; Yoshimoto M; Kasumi F; Akiyama F; Sakamoto G; Nakamura Y; Emi M
    Jpn J Cancer Res; 1997 Oct; 88(10):959-64. PubMed ID: 9414657
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Somatic in vivo alterations of the DPC4 gene at 18q21 in human lung cancers.
    Nagatake M; Takagi Y; Osada H; Uchida K; Mitsudomi T; Saji S; Shimokata K; Takahashi T; Takahashi T
    Cancer Res; 1996 Jun; 56(12):2718-20. PubMed ID: 8665501
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DPC4/SMAD4 gene alterations in human cancer, and their functional implications.
    Schutte M
    Ann Oncol; 1999; 10 Suppl 4():56-9. PubMed ID: 10436786
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Presence of multiple incontiguous deleted regions at the long arm of chromosome 18 in head and neck cancer.
    Papadimitrakopoulou VA; Oh Y; El-Naggar A; Izzo J; Clayman G; Mao L
    Clin Cancer Res; 1998 Mar; 4(3):539-44. PubMed ID: 9533520
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Allelic analysis of serous ovarian carcinoma reveals two putative tumor suppressor loci at 18q22-q23 distal to SMAD4, SMAD2, and DCC.
    Lassus H; Salovaara R; Aaltonen LA; Butzow R
    Am J Pathol; 2001 Jul; 159(1):35-42. PubMed ID: 11438451
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Transforming growth factor-beta responsiveness in DPC4/SMAD4-null cancer cells.
    Dai JL; Schutte M; Bansal RK; Wilentz RE; Sugar AY; Kern SE
    Mol Carcinog; 1999 Sep; 26(1):37-43. PubMed ID: 10487520
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathway.
    Woodford-Richens KL; Rowan AJ; Gorman P; Halford S; Bicknell DC; Wasan HS; Roylance RR; Bodmer WF; Tomlinson IP
    Proc Natl Acad Sci U S A; 2001 Aug; 98(17):9719-23. PubMed ID: 11481457
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Higher frequency of DPC4/Smad4 alterations in pancreatic cancer cell lines than in primary pancreatic adenocarcinomas.
    Bartsch D; Barth P; Bastian D; Ramaswamy A; Gerdes B; Chaloupka B; Deiss Y; Simon B; Schudy A
    Cancer Lett; 1999 May; 139(1):43-9. PubMed ID: 10408907
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells.
    Peng B; Fleming JB; Breslin T; Grau AM; Fojioka S; Abbruzzese JL; Evans DB; Ayers D; Wathen K; Wu T; Robertson KD; Chiao PJ
    Clin Cancer Res; 2002 Nov; 8(11):3628-38. PubMed ID: 12429655
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 40.