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7. Phenylalanine ammonia-lyase immobilized in microcapsules for the depletion of phenylalanine in plasma in phenylketonuric rat model. Bourget L; Chang TM Biochim Biophys Acta; 1986 Oct; 883(3):432-8. PubMed ID: 3756210 [TBL] [Abstract][Full Text] [Related]
8. Structure-based epitope and PEGylation sites mapping of phenylalanine ammonia-lyase for enzyme substitution treatment of phenylketonuria. Gámez A; Wang L; Sarkissian CN; Wendt D; Fitzpatrick P; Lemontt JF; Scriver CR; Stevens RC Mol Genet Metab; 2007 Aug; 91(4):325-34. PubMed ID: 17560821 [TBL] [Abstract][Full Text] [Related]
9. A new theory of enterorecirculation of amino acids and its use for depleting unwanted amino acids using oral enzyme-artificial cells, as in removing phenylalanine in phenylketonuria. Chang TM; Bourget L; Lister C Artif Cells Blood Substit Immobil Biotechnol; 1995; 23(1):1-21. PubMed ID: 7719440 [TBL] [Abstract][Full Text] [Related]
10. Effects of oral administration of artificial cells immobilized phenylalanine ammonia-lyase on intestinal amino acids of phenylketonuric rats. Bourget L; Chang TM Biomater Artif Cells Artif Organs; 1989; 17(2):161-81. PubMed ID: 2775877 [TBL] [Abstract][Full Text] [Related]
11. Partial rescue of neuropathology in the murine model of PKU following administration of recombinant phenylalanine ammonia lyase (pegvaliase). Goldfinger M; Zeile WL; Corado CR; O'Neill CA; Tsuruda LS; Laipis PJ; Cooper JD Mol Genet Metab; 2017 Sep; 122(1-2):33-35. PubMed ID: 28506393 [TBL] [Abstract][Full Text] [Related]
12. Depletion of phenylalanine in the blood of phenylketonuric patients using a PAL-enzyme reactor. An in vitro study. Ambrus CM; Horváth C; Kalghatgi K; Clowsley M; Huzella C; Warner R; Ambrus JL; Cooley CM; Mirand EA Res Commun Chem Pathol Pharmacol; 1982 Jul; 37(1):105-11. PubMed ID: 7122995 [TBL] [Abstract][Full Text] [Related]
13. Preservation of high phenylalanine ammonia lyase activities in roots of Japanese Striped corn: a potential oral therapeutic to treat phenylketonuria. López-Villalobos A; Lücker J; López-Quiróz AA; Yeung EC; Palma K; Kermode AR Cryobiology; 2014 Jun; 68(3):436-45. PubMed ID: 24657198 [TBL] [Abstract][Full Text] [Related]
14. Phenylalanine ammonia-lyase immobilized in semipermeable microcapsules for enzyme replacement in phenylketonuria. Bourget L; Chang TM FEBS Lett; 1985 Jan; 180(1):5-8. PubMed ID: 4038490 [TBL] [Abstract][Full Text] [Related]
15. Formulation and PEGylation optimization of the therapeutic PEGylated phenylalanine ammonia lyase for the treatment of phenylketonuria. Bell SM; Wendt DJ; Zhang Y; Taylor TW; Long S; Tsuruda L; Zhao B; Laipis P; Fitzpatrick PA PLoS One; 2017; 12(3):e0173269. PubMed ID: 28282402 [TBL] [Abstract][Full Text] [Related]
16. Evaluation of orally administered PEGylated phenylalanine ammonia lyase in mice for the treatment of Phenylketonuria. Sarkissian CN; Kang TS; Gámez A; Scriver CR; Stevens RC Mol Genet Metab; 2011 Nov; 104(3):249-54. PubMed ID: 21803624 [TBL] [Abstract][Full Text] [Related]
17. Biochemical properties and immunogenicity of L-phenylalanine ammonia-lyase: effects on tumor-bearing mice. Shen RS; Fritz RR; Abell CW Cancer Treat Rep; 1979 Jun; 63(6):1063-8. PubMed ID: 466645 [TBL] [Abstract][Full Text] [Related]
18. In vivo safety of hollow fiber enzyme-reactors with immobilized phenylalanine ammonia-lyase in a large animal model for phenylketonuria. Ambrus CM; Sharma SD; Horváth C; Kalghatgi K; Anthone S; Ambrus JL; Cooley C; Mirand EA J Pharmacol Exp Ther; 1983 Mar; 224(3):598-602. PubMed ID: 6681841 [TBL] [Abstract][Full Text] [Related]
19. Preclinical evaluation of multiple species of PEGylated recombinant phenylalanine ammonia lyase for the treatment of phenylketonuria. Sarkissian CN; Gámez A; Wang L; Charbonneau M; Fitzpatrick P; Lemontt JF; Zhao B; Vellard M; Bell SM; Henschell C; Lambert A; Tsuruda L; Stevens RC; Scriver CR Proc Natl Acad Sci U S A; 2008 Dec; 105(52):20894-9. PubMed ID: 19095795 [TBL] [Abstract][Full Text] [Related]
20. Pegvaliase for the treatment of phenylketonuria: Results of the phase 2 dose-finding studies with long-term follow-up. Burton BK; Longo N; Vockley J; Grange DK; Harding CO; Decker C; Li M; Lau K; Rosen O; Larimore K; Thomas J; Mol Genet Metab; 2020 Aug; 130(4):239-246. PubMed ID: 32593547 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]