189 related articles for article (PubMed ID: 8558511)
1. Characterizations of the unusual dissociation properties of melanotropin peptides from the melanocortin receptor, hMC1R.
Haskell-Luevano C; Miwa H; Dickinson C; Hadley ME; Hruby VJ; Yamada T; Gantz I
J Med Chem; 1996 Jan; 39(2):432-5. PubMed ID: 8558511
[TBL] [Abstract][Full Text] [Related]
2. Biological and conformational examination of stereochemical modifications using the template melanotropin peptide, Ac-Nle-c[Asp-His-Phe-Arg-Trp-Ala-Lys]-NH2, on human melanocortin receptors.
Haskell-Luevano C; Nikiforovich G; Sharma SD; Yang YK; Dickinson C; Hruby VJ; Gantz I
J Med Chem; 1997 May; 40(11):1738-48. PubMed ID: 9171884
[TBL] [Abstract][Full Text] [Related]
3. Three-dimensional molecular models of the hMC1R melanocortin receptor: complexes with melanotropin peptide agonists.
Haskell-Luevano C; Sawyer TK; Trumpp-Kallmeyer S; Bikker JA; Humblet C; Gantz I; Hruby VJ
Drug Des Discov; 1996 Dec; 14(3):197-211. PubMed ID: 9017363
[TBL] [Abstract][Full Text] [Related]
4. Cyclic lactam alpha-melanotropin analogues of Ac-Nle4-cyclo[Asp5, D-Phe7,Lys10] alpha-melanocyte-stimulating hormone-(4-10)-NH2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity at specific melanocortin receptors.
Hruby VJ; Lu D; Sharma SD; Castrucci AL; Kesterson RA; al-Obeidi FA; Hadley ME; Cone RD
J Med Chem; 1995 Sep; 38(18):3454-61. PubMed ID: 7658432
[TBL] [Abstract][Full Text] [Related]
5. Discovery of prototype peptidomimetic agonists at the human melanocortin receptors MC1R and MC4R.
Haskell-Luevano C; Hendrata S; North C; Sawyer TK; Hadley ME; Hruby VJ; Dickinson C; Gantz I
J Med Chem; 1997 Jul; 40(14):2133-9. PubMed ID: 9216831
[TBL] [Abstract][Full Text] [Related]
6. Potent and prolonged acting cyclic lactam analogues of alpha-melanotropin: design based on molecular dynamics.
Al-Obeidi F; Castrucci AM; Hadley ME; Hruby VJ
J Med Chem; 1989 Dec; 32(12):2555-61. PubMed ID: 2555512
[TBL] [Abstract][Full Text] [Related]
7. Potent and selective agonists of alpha-melanotropin (alphaMSH) action at human melanocortin receptor 5; linear analogs of alpha-melanotropin.
Bednarek MA; MacNeil T; Tang R; Fong TM; Cabello MA; Maroto M; Teran A
Peptides; 2007 May; 28(5):1020-8. PubMed ID: 17376561
[TBL] [Abstract][Full Text] [Related]
8. Discovery and structure-activity relationships of novel alpha-melanocyte-stimulating hormone inhibitors.
Sawyer TK; Staples DJ; Castrucci AM; Hadley ME
Pept Res; 1989; 2(1):140-6. PubMed ID: 2562482
[TBL] [Abstract][Full Text] [Related]
9. Binding and cAMP studies of melanotropin peptides with the cloned human peripheral melanocortin receptor, hMC1R.
Haskell-Luevano C; Miwa H; Dickinson C; Hruby VJ; Yamada T; Gantz I
Biochem Biophys Res Commun; 1994 Nov; 204(3):1137-42. PubMed ID: 7980588
[TBL] [Abstract][Full Text] [Related]
10. De novo design, synthesis, and pharmacology of alpha-melanocyte stimulating hormone analogues derived from somatostatin by a hybrid approach.
Han G; Haskell-Luevano C; Kendall L; Bonner G; Hadley ME; Cone RD; Hruby VJ
J Med Chem; 2004 Mar; 47(6):1514-26. PubMed ID: 14998337
[TBL] [Abstract][Full Text] [Related]
11. Structure-activity relationships of gamma-MSH analogues at the human melanocortin MC3, MC4, and MC5 receptors. Discovery of highly selective hMC3R, hMC4R, and hMC5R analogues.
Balse-Srinivasan P; Grieco P; Cai M; Trivedi D; Hruby VJ
J Med Chem; 2003 Nov; 46(23):4965-73. PubMed ID: 14584947
[TBL] [Abstract][Full Text] [Related]
12. Cysteine residues are involved in structure and function of melanocortin 1 receptor: Substitution of a cysteine residue in transmembrane segment two converts an agonist to antagonist.
Frändberg PA; Doufexis M; Kapas S; Chhajlani V
Biochem Biophys Res Commun; 2001 Mar; 281(4):851-7. PubMed ID: 11237737
[TBL] [Abstract][Full Text] [Related]
13. Dissection of the anti-inflammatory effect of the core and C-terminal (KPV) alpha-melanocyte-stimulating hormone peptides.
Getting SJ; Schiöth HB; Perretti M
J Pharmacol Exp Ther; 2003 Aug; 306(2):631-7. PubMed ID: 12750433
[TBL] [Abstract][Full Text] [Related]
14. Topographical modification of melanotropin peptide analogues with beta-methyltryptophan isomers at position 9 leads to differential potencies and prolonged biological activities.
Haskell-Luevano C; Boteju LW; Miwa H; Dickinson C; Gantz I; Yamada T; Hadley ME; Hruby VJ
J Med Chem; 1995 Nov; 38(23):4720-9. PubMed ID: 7473600
[TBL] [Abstract][Full Text] [Related]
15. Design of novel chimeric melanotropin-deltorphin analogues. Discovery of the first potent human melanocortin 1 receptor antagonist.
Han G; Quillan JM; Carlson K; Sadée W; Hruby VJ
J Med Chem; 2003 Feb; 46(5):810-9. PubMed ID: 12593660
[TBL] [Abstract][Full Text] [Related]
16. Comparative biological activities of potent analogues of alpha-melanotropin. Effect of nonaromatic and para substituted aromatic amino acids at position 7.
Wilkes BC; Cody WL; Hruby VJ; Castrucci AM; Hadley ME
Int J Pept Protein Res; 1986 Jun; 27(6):685-94. PubMed ID: 3489682
[TBL] [Abstract][Full Text] [Related]
17. Design of novel melanotropin agonists and antagonists with high potency and selectivity for human melanocortin receptors.
Cai M; Mayorov AV; Ying J; Stankova M; Trivedi D; Cabello C; Hruby VJ
Peptides; 2005 Aug; 26(8):1481-5. PubMed ID: 15876475
[TBL] [Abstract][Full Text] [Related]
18. Comparative biological activities of alpha-MSH antagonists in vertebrate pigment cells.
Castrucci AM; Almeida AL; al-Obeidi FA; Hadley ME; Hruby VJ; Staples DJ; Sawyer TK
Gen Comp Endocrinol; 1997 Mar; 105(3):410-6. PubMed ID: 9073503
[TBL] [Abstract][Full Text] [Related]
19. New melanocortin 1 receptor binding motif based on the C-terminal sequence of alpha-melanocyte-stimulating hormone.
Schiöth HB; Muceniece R; Mutule I; Wikberg JE
Basic Clin Pharmacol Toxicol; 2006 Oct; 99(4):287-93. PubMed ID: 17040213
[TBL] [Abstract][Full Text] [Related]
20. Identification of putative agouti-related protein(87-132)-melanocortin-4 receptor interactions by homology molecular modeling and validation using chimeric peptide ligands.
Wilczynski A; Wang XS; Joseph CG; Xiang Z; Bauzo RM; Scott JW; Sorensen NB; Shaw AM; Millard WJ; Richards NG; Haskell-Luevano C
J Med Chem; 2004 Apr; 47(9):2194-207. PubMed ID: 15084118
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
