149 related articles for article (PubMed ID: 8564408)
1. Amino hydroxamic acids as potent inhibitors of leukotriene A4 hydrolase.
Hogg JH; Ollmann IR; Haeggström JZ; Wetterholm A; Samuelsson B; Wong CH
Bioorg Med Chem; 1995 Oct; 3(10):1405-15. PubMed ID: 8564408
[TBL] [Abstract][Full Text] [Related]
2. Potent and selective inhibitors of leukotriene A4 hydrolase: effects on purified enzyme and human polymorphonuclear leukocytes.
Wetterholm A; Haeggström JZ; Samuelsson B; Yuan W; Munoz B; Wong CH
J Pharmacol Exp Ther; 1995 Oct; 275(1):31-7. PubMed ID: 7562564
[TBL] [Abstract][Full Text] [Related]
3. Development of selective tight-binding inhibitors of leukotriene A4 hydrolase.
Yuan W; Munoz B; Wong CH; Haeggström JZ; Wetterholm A; Samuelsson B
J Med Chem; 1993 Jan; 36(2):211-20. PubMed ID: 8423594
[TBL] [Abstract][Full Text] [Related]
4. Crystal structures of leukotriene A4 hydrolase in complex with captopril and two competitive tight-binding inhibitors.
Thunnissen MM; Andersson B; Samuelsson B; Wong CH; Haeggström J
FASEB J; 2002 Oct; 16(12):1648-50. PubMed ID: 12207002
[TBL] [Abstract][Full Text] [Related]
5. Zinc and other divalent cations inhibit purified leukotriene A4 hydrolase and leukotriene B4 biosynthesis in human polymorphonuclear leukocytes.
Wetterholm A; Macchia L; Haeggström JZ
Arch Biochem Biophys; 1994 Jun; 311(2):263-71. PubMed ID: 8203889
[TBL] [Abstract][Full Text] [Related]
6. Inhibitors of leukotriene A4 (LTA4) hydrolase as potential anti-inflammatory agents.
Penning TD
Curr Pharm Des; 2001 Feb; 7(3):163-79. PubMed ID: 11311111
[TBL] [Abstract][Full Text] [Related]
7. Binding of Pro-Gly-Pro at the active site of leukotriene A4 hydrolase/aminopeptidase and development of an epoxide hydrolase selective inhibitor.
Stsiapanava A; Olsson U; Wan M; Kleinschmidt T; Rutishauser D; Zubarev RA; Samuelsson B; Rinaldo-Matthis A; Haeggström JZ
Proc Natl Acad Sci U S A; 2014 Mar; 111(11):4227-32. PubMed ID: 24591641
[TBL] [Abstract][Full Text] [Related]
8. Effects of metalloproteinase inhibitors on leukotriene A4 hydrolase in human airway epithelial cells.
Baker JR; Kylstra TA; Bigby TD
Biochem Pharmacol; 1995 Sep; 50(7):905-12. PubMed ID: 7575672
[TBL] [Abstract][Full Text] [Related]
9. Development of a homogeneous time-resolved fluorescence leukotriene B4 assay for determining the activity of leukotriene A4 hydrolase.
Liang AM; Claret E; Ouled-Diaf J; Jean A; Vogel D; Light DR; Jones SW; Guilford WJ; Parkinson JF; Snider RM
J Biomol Screen; 2007 Jun; 12(4):536-45. PubMed ID: 17384330
[TBL] [Abstract][Full Text] [Related]
10. Novel structural and functional properties of leukotriene A4 hydrolase. Implications for the development of enzyme inhibitors.
Haeggström JZ; Wetterholm A; Medina JF; Samuelsson B
Adv Prostaglandin Thromboxane Leukot Res; 1994; 22():3-12. PubMed ID: 7771344
[TBL] [Abstract][Full Text] [Related]
11. Leukotriene A4 hydrolase. Inhibition by bestatin and intrinsic aminopeptidase activity establish its functional resemblance to metallohydrolase enzymes.
Orning L; Krivi G; Fitzpatrick FA
J Biol Chem; 1991 Jan; 266(3):1375-8. PubMed ID: 1846352
[TBL] [Abstract][Full Text] [Related]
12. Feasibility and physiological relevance of designing highly potent aminopeptidase-sparing leukotriene A4 hydrolase inhibitors.
Numao S; Hasler F; Laguerre C; Srinivas H; Wack N; Jäger P; Schmid A; Osmont A; Röthlisberger P; Houguenade J; Bergsdorf C; Dawson J; Carte N; Hofmann A; Markert C; Hardaker L; Billich A; Wolf RM; Penno CA; Bollbuck B; Miltz W; Röhn TA
Sci Rep; 2017 Oct; 7(1):13591. PubMed ID: 29051536
[TBL] [Abstract][Full Text] [Related]
13. Aminopeptidase B is structurally related to leukotriene-A4 hydrolase but is not a bifunctional enzyme with epoxide hydrolase activity.
Fukasawa KM; Fukasawa K; Harada M; Hirose J; Izumi T; Shimizu T
Biochem J; 1999 May; 339 ( Pt 3)(Pt 3):497-502. PubMed ID: 10215585
[TBL] [Abstract][Full Text] [Related]
14. Hybrid Receptor-Bound/MM-GBSA-Per-residue Energy-Based Pharmacophore Modelling: Enhanced Approach for Identification of Selective LTA4H Inhibitors as Potential Anti-inflammatory Drugs.
Appiah-Kubi P; Soliman M
Cell Biochem Biophys; 2017 Mar; 75(1):35-48. PubMed ID: 27914004
[TBL] [Abstract][Full Text] [Related]
15. Leukotriene A4 hydrolase: identification of a common carboxylate recognition site for the epoxide hydrolase and aminopeptidase substrates.
Rudberg PC; Tholander F; Andberg M; Thunnissen MM; Haeggström JZ
J Biol Chem; 2004 Jun; 279(26):27376-82. PubMed ID: 15078870
[TBL] [Abstract][Full Text] [Related]
16. Design and synthesis of Leukotriene A4 hydrolase inhibitors to alleviate idiopathic pulmonary fibrosis and acute lung injury.
Li X; Xie M; Lu C; Mao J; Cao Y; Yang Y; Wei Y; Liu X; Cao S; Song Y; Peng J; Zhou Y; Jiang Q; Lin G; Qin S; Qi M; Hou M; Liu X; Zhou H; Yang G; Yang C
Eur J Med Chem; 2020 Oct; 203():112614. PubMed ID: 32679453
[TBL] [Abstract][Full Text] [Related]
17. Omega-[(omega-arylalkyl)aryl]alkanoic acids: a new class of specific LTA4 hydrolase inhibitors.
Labaudinière R; Hilboll G; Leon-Lomeli A; Lautenschläger HH; Parnham M; Kuhl P; Dereu N
J Med Chem; 1992 Aug; 35(17):3156-69. PubMed ID: 1324315
[TBL] [Abstract][Full Text] [Related]
18. Leukotriene A4 hydrolase: mapping of a henicosapeptide involved in mechanism-based inactivation.
Mueller MJ; Wetterholm A; Blomster M; Jörnvall H; Samuelsson B; Haeggström JZ
Proc Natl Acad Sci U S A; 1995 Aug; 92(18):8383-7. PubMed ID: 7667299
[TBL] [Abstract][Full Text] [Related]
19. Saccharomyces cerevisiae leukotriene A4 hydrolase: formation of leukotriene B4 and identification of catalytic residues.
Kull F; Ohlson E; Lind B; Haeggström JZ
Biochemistry; 2001 Oct; 40(42):12695-703. PubMed ID: 11601994
[TBL] [Abstract][Full Text] [Related]
20. Leukotriene A5 is a substrate and an inhibitor of rat and human neutrophil LTA4 hydrolase.
Nathaniel DJ; Evans JF; Leblanc Y; Léveillé C; Fitzsimmons BJ; Ford-Hutchinson AW
Biochem Biophys Res Commun; 1985 Sep; 131(2):827-35. PubMed ID: 2996528
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
