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2. Higher frequency of aberrant crypt foci in rapid than slow acetylator inbred rats administered the colon carcinogen 3,2'-dimethyl-4-aminobiphenyl. Feng Y; Fretland AJ; Rustan TD; Jiang W; Becker WK; Hein DW Toxicol Appl Pharmacol; 1997 Nov; 147(1):56-62. PubMed ID: 9356307 [TBL] [Abstract][Full Text] [Related]
3. Metabolic activation of N-hydroxy-2-aminofluorene and N-hydroxy-2-acetylaminofluorene by monomorphic N-acetyltransferase (NAT1) and polymorphic N-acetyltransferase (NAT2) in colon cytosols of Syrian hamsters congenic at the NAT2 locus. Hein DW; Doll MA; Gray K; Rustan TD; Ferguson RJ Cancer Res; 1993 Feb; 53(3):509-14. PubMed ID: 8425184 [TBL] [Abstract][Full Text] [Related]
4. Polymorphic and monomorphic expression of arylamine carcinogen N-acetyltransferase isozymes in tumor target organ cytosols of Syrian hamsters congenic at the polymorphic acetyltransferase locus. Hein DW; Rustan TD; Bucher KD; Miller LS J Pharmacol Exp Ther; 1991 Nov; 259(2):699-704. PubMed ID: 1941618 [TBL] [Abstract][Full Text] [Related]
5. Construction of Syrian hamster lines congenic at the polymorphic acetyltransferase locus (NAT2): acetylator genotype-dependent N- and O-acetylation of arylamine carcinogens. Hein DW; Doll MA; Rustan TD; Gray K; Ferguson RJ; Feng Y Toxicol Appl Pharmacol; 1994 Jan; 124(1):16-24. PubMed ID: 8291057 [TBL] [Abstract][Full Text] [Related]
6. Effect of acetylator genotype on 3,2'-dimethyl-4-aminobiphenyl induced aberrant crypt foci in the colon of hamsters. Paulsen JE; Steffensen IL; Namork E; Hein DW; Alexander J Carcinogenesis; 1996 Mar; 17(3):459-65. PubMed ID: 8631131 [TBL] [Abstract][Full Text] [Related]
7. Acetylator genotype-dependent formation of 2-aminofluorene-hemoglobin adducts in rapid and slow acetylator Syrian hamsters congenic at the NAT2 locus. Feng Y; Rustan TD; Ferguson RJ; Doll MA; Hein DW Toxicol Appl Pharmacol; 1994 Jan; 124(1):10-5. PubMed ID: 8291051 [TBL] [Abstract][Full Text] [Related]
8. 3,2'-Dimethyl-4-aminobiphenyl-DNA adduct formation in tumor target and nontarget organs of rapid and slow acetylator Syrian hamsters cogenic at the NAT2 locus. Feng Y; Jiang W; Deitz AC; Hein DW Toxicol Appl Pharmacol; 1996 Oct; 140(2):315-21. PubMed ID: 8887447 [TBL] [Abstract][Full Text] [Related]
9. Dietary selenium reduces the formation of aberrant crypts in rats administered 3,2'-dimethyl-4-aminobiphenyl. Feng Y; Finley JW; Davis CD; Becker WK; Fretland AJ; Hein DW Toxicol Appl Pharmacol; 1999 May; 157(1):36-42. PubMed ID: 10329505 [TBL] [Abstract][Full Text] [Related]
10. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine induces a higher number of aberrant crypt foci in Fischer 344 (rapid) than in Wistar Kyoto (slow) acetylator inbred rats. Purewal M; Velasco M; Fretland AJ; Hein DW; Wargovich MJ Cancer Epidemiol Biomarkers Prev; 2000 May; 9(5):529-32. PubMed ID: 10815700 [TBL] [Abstract][Full Text] [Related]
11. DNA adduct levels and intestinal lesions in congenic rapid and slow acetylator syrian hamsters admi food mutagens 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) or 2-amino-3-methylimidazo[4,5-f]quinoline (IQ). Steffensen IL; Fretland AJ; Paulsen JE; Feng Y; Eide TJ; Devanaboyina US; Hein DW; Alexander J Pharmacol Toxicol; 2000 Jun; 86(6):257-63. PubMed ID: 10895988 [TBL] [Abstract][Full Text] [Related]
12. 2-Aminofluorene-DNA adduct levels in tumor-target and nontarget organs of rapid and slow acetylator Syrian hamsters congenic at the NAT2 locus. Feng Y; Jiang W; Hein DW Toxicol Appl Pharmacol; 1996 Nov; 141(1):248-55. PubMed ID: 8917697 [TBL] [Abstract][Full Text] [Related]
13. Acetylator genotype-dependent expression of arylamine N-acetyltransferase and N-hydroxyarylamine O-acetyltransferase in Syrian inbred hamster intestine and colon. Identity with the hepatic acetylation polymorphism. Ogolla F; Ferguson RJ; Kirlin WG; Trinidad A; Andrews AF; Mpezo M; Hein DW Drug Metab Dispos; 1990; 18(5):680-5. PubMed ID: 1981720 [TBL] [Abstract][Full Text] [Related]
14. Acetylator genotype-dependent expression of arylamine N-acetyltransferase in human colon cytosol from non-cancer and colorectal cancer patients. Kirlin WG; Ogolla F; Andrews AF; Trinidad A; Ferguson RJ; Yerokun T; Mpezo M; Hein DW Cancer Res; 1991 Jan; 51(2):549-55. PubMed ID: 1985773 [TBL] [Abstract][Full Text] [Related]
15. Cloning, sequencing, and recombinant expression of NAT1, NAT2, and NAT3 derived from the C3H/HeJ (rapid) and A/HeJ (slow) acetylator inbred mouse: functional characterization of the activation and deactivation of aromatic amine carcinogens. Fretland AJ; Doll MA; Gray K; Feng Y; Hein DW Toxicol Appl Pharmacol; 1997 Feb; 142(2):360-6. PubMed ID: 9070359 [TBL] [Abstract][Full Text] [Related]
16. Genetic control of acetyl coenzyme A-dependent arylamine N-acetyltransferase, hydrazine N-acetyltransferase, and N-hydroxy-arylamine O-acetyltransferase enzymes in C57BL/6J, A/J, AC57F1, and the rapid and slow acetylator A.B6 and B6.A congenic inbred mouse. Hein DW; Trinidad A; Yerokun T; Ferguson RJ; Kirlin WG; Weber WW Drug Metab Dispos; 1988; 16(3):341-7. PubMed ID: 2900723 [TBL] [Abstract][Full Text] [Related]
17. Higher DNA adduct levels in urinary bladder and prostate of slow acetylator inbred rats administered 3,2'-dimethyl-4-aminobiphenyl. Jiang W; Feng Y; Hein DW Toxicol Appl Pharmacol; 1999 May; 156(3):187-94. PubMed ID: 10222311 [TBL] [Abstract][Full Text] [Related]
18. Foci of aberrant crypts in the colons of mice and rats exposed to carcinogens associated with foods. Tudek B; Bird RP; Bruce WR Cancer Res; 1989 Mar; 49(5):1236-40. PubMed ID: 2917353 [TBL] [Abstract][Full Text] [Related]
19. Oral administration of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) yields PhIP-DNA adducts but not tumors in male Syrian hamsters congenic at the N-acetyltransferase 2 (NAT2) locus. Fretland AJ; Devanaboyina US; Feng Y; Leff MA; Xiao GH; Webb SJ; Hein DW Toxicol Sci; 2001 Feb; 59(2):226-30. PubMed ID: 11158715 [TBL] [Abstract][Full Text] [Related]