787 related articles for article (PubMed ID: 8568804)
1. New sigma and 5-HT1A receptor ligands: omega-(tetralin-1-yl)-n-alkylamine derivatives.
Berardi F; Colabufo NA; Giudice G; Perrone R; Tortorella V; Govoni S; Lucchi L
J Med Chem; 1996 Jan; 39(1):176-82. PubMed ID: 8568804
[TBL] [Abstract][Full Text] [Related]
2. Novel potent sigma 1 ligands: N-[omega-(tetralin-1-yl)alkyl]piperidine derivatives.
Berardi F; Giudice G; Perrone R; Tortorella V; Govoni S; Lucchi L
J Med Chem; 1996 Oct; 39(21):4255-60. PubMed ID: 8863803
[TBL] [Abstract][Full Text] [Related]
3. Structure-affinity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinealkylamides, a new class of 5-hydroxytryptamine7 receptor agents.
Leopoldo M; Berardi F; Colabufo NA; Contino M; Lacivita E; Niso M; Perrone R; Tortorella V
J Med Chem; 2004 Dec; 47(26):6616-24. PubMed ID: 15588097
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and structure-activity relationships of a new model of arylpiperazines. 4. 1-[omega-(4-Arylpiperazin-1-yl)alkyl]-3-(diphenylmethylene) - 2, 5-pyrrolidinediones and -3-(9H-fluoren-9-ylidene)-2, 5-pyrrolidinediones: study of the steric requirements of the terminal amide fragment on 5-HT1A affinity/selectivity.
López-Rodríguez ML; Morcillo MJ; Rovat TK; Fernández E; Vicente B; Sanz AM; Hernández M; Orensanz L
J Med Chem; 1999 Jan; 42(1):36-49. PubMed ID: 9888831
[TBL] [Abstract][Full Text] [Related]
5. 1-aryl-4-[(5-methoxy-1,2,3, 4-tetrahydronaphthalen-1-yl)alkyl]piperazines and their analogues: influence of the stereochemistry of the tetrahydronaphthalen-1-yl nucleus on 5-HT1A receptor affinity and selectivity versus alpha1 and D2 receptors. 5.
Perrone R; Berardi F; Colabufo NA; Leopoldo M; Tortorella V
J Med Chem; 1999 Feb; 42(3):490-6. PubMed ID: 9986719
[TBL] [Abstract][Full Text] [Related]
6. N-[omega-(Tetralin-1-yl)alkyl] derivatives of 3,3-dimethylpiperidine are highly potent and selective sigma1 or sigma2 ligands.
Berardi F; Santoro S; Perrone R; Tortorella V; Govoni S; Lucchi L
J Med Chem; 1998 Oct; 41(21):3940-7. PubMed ID: 9767631
[TBL] [Abstract][Full Text] [Related]
7. 4-(tetralin-1-yl)- and 4-(naphthalen-1-yl)alkyl derivatives of 1-cyclohexylpiperazine as sigma receptor ligands with agonist sigma2 activity.
Berardi F; Ferorelli S; Abate C; Colabufo NA; Contino M; Perrone R; Tortorella V
J Med Chem; 2004 Apr; 47(9):2308-17. PubMed ID: 15084129
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and structure-activity relationships of a new model of arylpiperazines. 1. 2-[[4-(o-methoxyphenyl)piperazin-1-yl]methyl]-1, 3-dioxoperhydroimidazo[1,5-alpha]pyridine: a selective 5-HT1A receptor agonist.
López-Rodríguez ML; Rosado ML; Benhamú B; Morcillo MJ; Sanz AM; Orensanz L; Beneitez ME; Fuentes JA; Manzanares J
J Med Chem; 1996 Oct; 39(22):4439-50. PubMed ID: 8893838
[TBL] [Abstract][Full Text] [Related]
9. 5-HT1A-versus D2-receptor selectivity of flesinoxan and analogous N4-substituted N1-arylpiperazines.
Kuipers W; Kruse CG; van Wijngaarden I; Standaar PJ; Tulp MT; Veldman N; Spek AL; IJzerman AP
J Med Chem; 1997 Jan; 40(3):300-12. PubMed ID: 9022796
[TBL] [Abstract][Full Text] [Related]
10. Structure-activity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinehexanamides, a class of 5-HT7 receptor agents. 2.
Leopoldo M; Lacivita E; Contino M; Colabufo NA; Berardi F; Perrone R
J Med Chem; 2007 Aug; 50(17):4214-21. PubMed ID: 17649988
[TBL] [Abstract][Full Text] [Related]
11. 1-aryl-4-[(1-tetralinyl)alkyl]piperazines: alkylamido and alkylamino derivatives. Synthesis, 5-HT1A receptor affinity, and selectivity. 3.
Perrone R; Berardi F; Leopoldo M; Tortorella V; Fornaretto MG; Caccia C; McArthur RA
J Med Chem; 1996 Aug; 39(16):3195-202. PubMed ID: 8759642
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and structure-activity relationships of a new model of arylpiperazines. 3.1 2-[omega-(4-arylpiperazin-1-yl)alkyl]perhydropyrrolo- [1,2-c]imidazoles and -perhydroimidazo[1,5-a]pyridines: study of the influence of the terminal amide fragment on 5-HT1A affinity/selectivity.
López-Rodríguez ML; Morcillo MJ; Fernández E; Porras E; Murcia M; Sanz AM; Orensanz L
J Med Chem; 1997 Aug; 40(16):2653-6. PubMed ID: 9258372
[TBL] [Abstract][Full Text] [Related]
13. [[(Arylpiperazinyl)alkyl]thio]thieno[2,3-d]pyrimidinone derivatives as high-affinity, selective 5-HT1A receptor ligands.
Modica M; Santagati M; Russo F; Parotti L; De Gioia L; Selvaggini C; Salmona M; Mennini T
J Med Chem; 1997 Feb; 40(4):574-85. PubMed ID: 9046348
[TBL] [Abstract][Full Text] [Related]
14. Effect of linking bridge modifications on the 5-HT1A receptor activity of some 4-(omega-benzotriazol-1-yl)alkyl-1-(2-methoxy-phenyl)piperazines.
Paluchowska MH; Kłodzińska A; Tatarczyńska E; Szaro A; Chojnacka-Wójcik E
Pol J Pharmacol; 1998; 50(4-5):341-7. PubMed ID: 10091719
[TBL] [Abstract][Full Text] [Related]
15. Design and synthesis of a series of 6-substituted-2-pyridinylmethylamine derivatives as novel, high-affinity, selective agonists at 5-HT1A receptors.
Vacher B; Bonnaud B; Funes P; Jubault N; Koek W; Assié MB; Cosi C
J Med Chem; 1998 Dec; 41(25):5070-83. PubMed ID: 9836623
[TBL] [Abstract][Full Text] [Related]
16. Exploring the importance of piperazine N-atoms for sigma(2) receptor affinity and activity in a series of analogs of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28).
Berardi F; Abate C; Ferorelli S; Uricchio V; Colabufo NA; Niso M; Perrone R
J Med Chem; 2009 Dec; 52(23):7817-28. PubMed ID: 19842660
[TBL] [Abstract][Full Text] [Related]
17. 1-Aryl-4-(4-succinimidobutyl)piperazines and their conformationally constrained analogues: synthesis, binding to serotonin (5-HT1A, 5-HT2A, 5-HT7), alpha1-adrenergic, and dopaminergic D2 receptors, and in vivo 5-HT1A functional characteristics.
Bojarski AJ; Paluchowska MH; Duszyńska B; Kłodzińska A; Tatarczyńska E; Chojnacka-Wójcik E
Bioorg Med Chem; 2005 Mar; 13(6):2293-303. PubMed ID: 15727878
[TBL] [Abstract][Full Text] [Related]
18. Characterization of novel N,N'-disubstituted piperazines as sigma receptor ligands.
Zhang Y; Williams W; Torrence-Campbell C; Bowen WD; Rice KC
J Med Chem; 1998 Dec; 41(25):4950-7. PubMed ID: 9836612
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and quantitative structure-activity relationships of N-(1-benzylpiperidin-4-yl)phenylacetamides and related analogues as potent and selective sigma1 receptor ligands.
Huang Y; Hammond PS; Whirrett BR; Kuhner RJ; Wu L; Childers SR; Mach RH
J Med Chem; 1998 Jun; 41(13):2361-70. PubMed ID: 9632369
[TBL] [Abstract][Full Text] [Related]
20. New benzocycloalkylpiperazines, potent and selective 5-HT1A receptor ligands.
el Ahmad Y; Laurent E; Maillet P; Talab A; Teste JF; Dokhan R; Tran G; Ollivier R
J Med Chem; 1997 Mar; 40(6):952-60. PubMed ID: 9083484
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]