BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

386 related articles for article (PubMed ID: 8580378)

  • 21. Identification of a variable region within the cytoplasmic tail of the IL-2 receptor beta chain that is required for growth signal transduction.
    Liu KD; Lai SY; Goldsmith MA; Greene WC
    J Biol Chem; 1995 Sep; 270(38):22176-81. PubMed ID: 7545674
    [TBL] [Abstract][Full Text] [Related]  

  • 22. JAK3 protein tyrosine kinase mediates interleukin-7-induced activation of phosphatidylinositol-3' kinase.
    Sharfe N; Dadi HK; Roifman CM
    Blood; 1995 Sep; 86(6):2077-85. PubMed ID: 7662955
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Molecular role of TGF-beta, secreted from a new type of CD4+ suppressor T cell, NY4.2, in the prevention of autoimmune IDDM in NOD mice.
    Han HS; Jun HS; Utsugi T; Yoon JW
    J Autoimmun; 1997 Jun; 10(3):299-307. PubMed ID: 9218758
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Receptors for interleukin (IL)-4 do not associate with the common gamma chain, and IL-4 induces the phosphorylation of JAK2 tyrosine kinase in human colon carcinoma cells.
    Murata T; Noguchi PD; Puri RK
    J Biol Chem; 1995 Dec; 270(51):30829-36. PubMed ID: 8530527
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Tumor-induced suppression of T lymphocyte proliferation coincides with inhibition of Jak3 expression and IL-2 receptor signaling: role of soluble products from human renal cell carcinomas.
    Kolenko V; Wang Q; Riedy MC; O'Shea J; Ritz J; Cathcart MK; Rayman P; Tubbs R; Edinger M; Novick A; Bukowski R; Finke J
    J Immunol; 1997 Sep; 159(6):3057-67. PubMed ID: 9300731
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Simultaneous activation of JAK1 and JAK2 confers IL-3 independent growth on Ba/F3 pro-B cells.
    Huang HM; Lin YL; Chen CH; Chang TW
    J Cell Biochem; 2005 Oct; 96(2):361-75. PubMed ID: 15988755
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Regulation of IL-2 signaling.
    Higuchi M; Asao H; Tanaka N; Oda K; Takeshita T; Sugamura K
    Leukemia; 1997 Apr; 11 Suppl 3():416-7. PubMed ID: 9209410
    [TBL] [Abstract][Full Text] [Related]  

  • 28. The common gamma chain (gamma c) is a required signaling component of the IL-21 receptor and supports IL-21-induced cell proliferation via JAK3.
    Habib T; Senadheera S; Weinberg K; Kaushansky K
    Biochemistry; 2002 Jul; 41(27):8725-31. PubMed ID: 12093291
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Acute lymphoblastic leukemia-associated JAK1 mutants activate the Janus kinase/STAT pathway via interleukin-9 receptor alpha homodimers.
    Hornakova T; Staerk J; Royer Y; Flex E; Tartaglia M; Constantinescu SN; Knoops L; Renauld JC
    J Biol Chem; 2009 Mar; 284(11):6773-81. PubMed ID: 19139102
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The pseudokinase domain is required for suppression of basal activity of Jak2 and Jak3 tyrosine kinases and for cytokine-inducible activation of signal transduction.
    Saharinen P; Silvennoinen O
    J Biol Chem; 2002 Dec; 277(49):47954-63. PubMed ID: 12351625
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Immobilization of glycosylphosphatidylinositol-anchored proteins inhibits T cell growth but not function.
    Marmor MD; Bachmann MF; Ohashi PS; Malek TR; Julius M
    Int Immunol; 1999 Sep; 11(9):1381-93. PubMed ID: 10464159
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Adenosine acts through A2 receptors to inhibit IL-2-induced tyrosine phosphorylation of STAT5 in T lymphocytes: role of cyclic adenosine 3',5'-monophosphate and phosphatases.
    Zhang H; Conrad DM; Butler JJ; Zhao C; Blay J; Hoskin DW
    J Immunol; 2004 Jul; 173(2):932-44. PubMed ID: 15240680
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl.
    Carlesso N; Frank DA; Griffin JD
    J Exp Med; 1996 Mar; 183(3):811-20. PubMed ID: 8642285
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Human lung myofibroblasts as effectors of the inflammatory process: the common receptor gamma chain is induced by Th2 cytokines, and CD40 ligand is induced by lipopolysaccharide, thrombin and TNF-alpha.
    Doucet C; Giron-Michel J; Canonica GW; Azzarone B
    Eur J Immunol; 2002 Sep; 32(9):2437-49. PubMed ID: 12207328
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12.
    Bacon CM; McVicar DW; Ortaldo JR; Rees RC; O'Shea JJ; Johnston JA
    J Exp Med; 1995 Jan; 181(1):399-404. PubMed ID: 7528775
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Signaling via IL-2 and IL-4 in JAK3-deficient severe combined immunodeficiency lymphocytes: JAK3-dependent and independent pathways.
    Oakes SA; Candotti F; Johnston JA; Chen YQ; Ryan JJ; Taylor N; Liu X; Hennighausen L; Notarangelo LD; Paul WE; Blaese RM; O'Shea JJ
    Immunity; 1996 Dec; 5(6):605-15. PubMed ID: 8986719
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Distinct Acute Lymphoblastic Leukemia (ALL)-associated Janus Kinase 3 (JAK3) Mutants Exhibit Different Cytokine-Receptor Requirements and JAK Inhibitor Specificities.
    Losdyck E; Hornakova T; Springuel L; Degryse S; Gielen O; Cools J; Constantinescu SN; Flex E; Tartaglia M; Renauld JC; Knoops L
    J Biol Chem; 2015 Nov; 290(48):29022-34. PubMed ID: 26446793
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Efficient internalization of IL-2 depends on the distal portion of the cytoplasmic tail of the IL-2R common gamma-chain and a lymphoid cell environment.
    Yu A; Olosz F; Choi CY; Malek TR
    J Immunol; 2000 Sep; 165(5):2556-62. PubMed ID: 10946282
    [TBL] [Abstract][Full Text] [Related]  

  • 39. SOCS-3 is tyrosine phosphorylated in response to interleukin-2 and suppresses STAT5 phosphorylation and lymphocyte proliferation.
    Cohney SJ; Sanden D; Cacalano NA; Yoshimura A; Mui A; Migone TS; Johnston JA
    Mol Cell Biol; 1999 Jul; 19(7):4980-8. PubMed ID: 10373548
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Pyk2 is a downstream mediator of the IL-2 receptor-coupled Jak signaling pathway.
    Miyazaki T; Takaoka A; Nogueira L; Dikic I; Fujii H; Tsujino S; Mitani Y; Maeda M; Schlessinger J; Taniguchi T
    Genes Dev; 1998 Mar; 12(6):770-5. PubMed ID: 9512511
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 20.