102 related articles for article (PubMed ID: 8591725)
1. Metabolism and pharmacokinetics of a double prodrug of ganciclovir in the rat and monkey.
Krasny HC; Beauchamp L; Krenitsky TA; de Miranda P
Drug Metab Dispos; 1995 Nov; 23(11):1242-7. PubMed ID: 8591725
[TBL] [Abstract][Full Text] [Related]
2. Ocular disposition of novel lipophilic diester prodrugs of ganciclovir following intravitreal administration using microdialysis.
Macha S; Duvvuri S; Mitra AK
Curr Eye Res; 2004 Feb; 28(2):77-84. PubMed ID: 14972713
[TBL] [Abstract][Full Text] [Related]
3. Synthesis, physicochemical properties and antiviral activities of ester prodrugs of ganciclovir.
Patel K; Trivedi S; Luo S; Zhu X; Pal D; Kern ER; Mitra AK
Int J Pharm; 2005 Nov; 305(1-2):75-89. PubMed ID: 16242278
[TBL] [Abstract][Full Text] [Related]
4. Intravitreal toxicology and duration of efficacy of a novel antiviral lipid prodrug of ganciclovir in liposome formulation.
Cheng L; Hostetler KY; Chaidhawangul S; Gardner MF; Beadle JR; Keefe KS; Bergeron-Lynn G; Severson GM; Soules KA; Mueller AJ; Freeman WR
Invest Ophthalmol Vis Sci; 2000 May; 41(6):1523-32. PubMed ID: 10798672
[TBL] [Abstract][Full Text] [Related]
5. Corneal permeation of ganciclovir: mechanism of ganciclovir permeation enhancement by acyl ester prodrug design.
Tirucherai GS; Dias C; Mitra AK
J Ocul Pharmacol Ther; 2002 Dec; 18(6):535-48. PubMed ID: 12537680
[TBL] [Abstract][Full Text] [Related]
6. Superior cytostatic activity of the ganciclovir elaidic acid ester due to the prolonged intracellular retention of ganciclovir anabolites in herpes simplex virus type 1 thymidine kinase gene-transfected tumor cells.
Balzarini J; Degrève B; Andrei G; Neyts J; Sandvold M; Myhren F; de Clercq E
Gene Ther; 1998 Mar; 5(3):419-26. PubMed ID: 9614564
[TBL] [Abstract][Full Text] [Related]
7. Pharmacokinetics and metabolism of the prodrug DB289 (2,5-bis[4-(N-methoxyamidino)phenyl]furan monomaleate) in rat and monkey and its conversion to the antiprotozoal/antifungal drug DB75 (2,5-bis(4-guanylphenyl)furan dihydrochloride).
Midgley I; Fitzpatrick K; Taylor LM; Houchen TL; Henderson SJ; Wright SJ; Cybulski ZR; John BA; McBurney A; Boykin DW; Trendler KL
Drug Metab Dispos; 2007 Jun; 35(6):955-67. PubMed ID: 17360833
[TBL] [Abstract][Full Text] [Related]
8. Pharmacokinetics of latanoprost in the cynomolgus monkey. 1st communication: single intravenous, oral or topical administration on the eye.
Sjöquist B; Tajallaei S; Stjernschantz J
Arzneimittelforschung; 1999 Mar; 49(3):225-33. PubMed ID: 10219466
[TBL] [Abstract][Full Text] [Related]
9. Metabolic fate and pharmacokinetics of the acyclovir prodrug valaciclovir in cynomolgus monkeys.
de Miranda P; Burnette TC
Drug Metab Dispos; 1994; 22(1):55-9. PubMed ID: 8149890
[TBL] [Abstract][Full Text] [Related]
10. Vitreal pharmacokinetics of dipeptide monoester prodrugs of ganciclovir.
Majumdar S; Kansara V; Mitra AK
J Ocul Pharmacol Ther; 2006 Aug; 22(4):231-41. PubMed ID: 16910863
[TBL] [Abstract][Full Text] [Related]
11. Characterization of a novel intraocular drug-delivery system using crystalline lipid antiviral prodrugs of ganciclovir and cyclic cidofovir.
Cheng L; Hostetler KY; Lee J; Koh HJ; Beadle JR; Bessho K; Toyoguchi M; Aldern K; Bovet JM; Freeman WR
Invest Ophthalmol Vis Sci; 2004 Nov; 45(11):4138-44. PubMed ID: 15505067
[TBL] [Abstract][Full Text] [Related]
12. Ocular disposition of ganciclovir and its monoester prodrugs following intravitreal administration using microdialysis.
Macha S; Mitra AK
Drug Metab Dispos; 2002 Jun; 30(6):670-5. PubMed ID: 12019194
[TBL] [Abstract][Full Text] [Related]
13. Species and organ differences in first-pass metabolism of the ester prodrug L-751,164 in dogs and monkeys. In vivo and in vitro studies.
Prueksaritanont T; Gorham LM; Ellis JD; Fernandez-Metzler C; Deluna P; Gehret JR; Strong KL; Hochman JH; Askew BC; Duggan ME; Gilbert JD; Lin JH; Vyas KP
Drug Metab Dispos; 1996 Nov; 24(11):1263-71. PubMed ID: 8937862
[TBL] [Abstract][Full Text] [Related]
14. Pharmacokinetics and safety of viramidine, a prodrug of ribavirin, in healthy volunteers.
Lin CC; Philips L; Xu C; Yeh LT
J Clin Pharmacol; 2004 Mar; 44(3):265-75. PubMed ID: 14973309
[TBL] [Abstract][Full Text] [Related]
15. Corneal absorption and anterior chamber pharmacokinetics of dipeptide monoester prodrugs of ganciclovir (GCV): in vivo comparative evaluation of these prodrugs with Val-GCV and GCV in rabbits.
Gunda S; Hariharan S; Mitra AK
J Ocul Pharmacol Ther; 2006 Dec; 22(6):465-76. PubMed ID: 17238815
[TBL] [Abstract][Full Text] [Related]
16. In vitro and in vivo evaluations of the metabolism, pharmacokinetics, and bioavailability of ester prodrugs of L-767,679, a potent fibrinogen receptor antagonist: an approach for the selection of a prodrug candidate.
Prueksaritanont T; Gorham LM; Breslin MJ; Hutchinson JH; Hartman GD; Vyas KP; Baillie TA
Drug Metab Dispos; 1997 Aug; 25(8):978-84. PubMed ID: 9280406
[TBL] [Abstract][Full Text] [Related]
17. Pharmacokinetics of latanoprost in the cynomolgus monkey. 2nd communication: repeated topical administration on the eye.
Sjöquist B; Uhlin A; Byding P; Stjernschantz J
Arzneimittelforschung; 1999 Mar; 49(3):234-9. PubMed ID: 10219467
[TBL] [Abstract][Full Text] [Related]
18. [Ocular pharmacokinetics and bioavailability of 0.2% ganciclovir in-situ gelling eye drops].
Zhang JJ; Gao CF; Wang LY
Zhonghua Yan Ke Za Zhi; 2006 Jul; 42(7):637-41. PubMed ID: 17081425
[TBL] [Abstract][Full Text] [Related]
19. Molecular imaging with 123I-FIAU, 18F-FUdR, 18F-FET, and 18F-FDG for monitoring herpes simplex virus type 1 thymidine kinase and ganciclovir prodrug activation gene therapy of cancer.
Wang HE; Yu HM; Liu RS; Lin M; Gelovani JG; Hwang JJ; Wei HJ; Deng WP
J Nucl Med; 2006 Jul; 47(7):1161-71. PubMed ID: 16818951
[TBL] [Abstract][Full Text] [Related]
20. The role of a HSV thymidine kinase stimulating substance, scopadulciol, in improving the efficacy of cancer gene therapy.
Hayashi K; Lee JB; Maitani Y; Toyooka N; Nemoto H; Hayashi T
J Gene Med; 2006 Aug; 8(8):1056-67. PubMed ID: 16779868
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
