BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 8596537)

  • 1. Effects of DNA topoisomerase inhibitors on nonhomologous and homologous recombination in mammalian cells.
    Aratani Y; Andoh T; Koyama H
    Mutat Res; 1996 Feb; 362(2):181-91. PubMed ID: 8596537
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Deletion and duplication sequences induced in CHO cells by teniposide (VM-26), a topoisomerase II targeting drug, can be explained by the processing of DNA nicks produced by the drug-topoisomerase interaction.
    Ripley LS
    Mutat Res; 1994 Apr; 312(2):67-78. PubMed ID: 7510833
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chinese hamster ovary cells resistant to the topoisomerase II catalytic inhibitor ICRF-159: a Tyr49Phe mutation confers high-level resistance to bisdioxopiperazines.
    Sehested M; Wessel I; Jensen LH; Holm B; Oliveri RS; Kenwrick S; Creighton AM; Nitiss JL; Jensen PB
    Cancer Res; 1998 Apr; 58(7):1460-8. PubMed ID: 9537249
    [TBL] [Abstract][Full Text] [Related]  

  • 4. RAD51 supports spontaneous non-homologous recombination in mammalian cells, but not the corresponding process induced by topoisomerase inhibitors.
    Arnaudeau C; Rozier L; Cazaux C; Defais M; Jenssen D; Helleday T
    Nucleic Acids Res; 2001 Feb; 29(3):662-7. PubMed ID: 11160887
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Camptothecin enhances random integration of transfected DNA into the genome of mammalian cells.
    Shcherbakova OG; Filatov MV
    Biochim Biophys Acta; 2000 Jan; 1495(1):1-3. PubMed ID: 10634926
    [TBL] [Abstract][Full Text] [Related]  

  • 6. End extension repair of introduced targeting vectors mediated by homologous recombination in mammalian cells.
    Aratani Y; Okazaki R; Koyama H
    Nucleic Acids Res; 1992 Sep; 20(18):4795-801. PubMed ID: 1408793
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DNA topoisomerase II inhibitors enhance random integration of transfected vectors into human chromosomes.
    Fujimaki K; Aratani Y; Fujisawa S; Motomura S; Okubo T; Koyama H
    Somat Cell Mol Genet; 1996 Jul; 22(4):279-90. PubMed ID: 9000172
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hypersensitivity of nonhomologous DNA end-joining mutants to VP-16 and ICRF-193: implications for the repair of topoisomerase II-mediated DNA damage.
    Adachi N; Suzuki H; Iiizumi S; Koyama H
    J Biol Chem; 2003 Sep; 278(38):35897-902. PubMed ID: 12842886
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inactivation of topoisomerase I or II may lead to recombination or to aberrant replication termination on both SV40 and yeast 2 micron DNA.
    Levac P; Moss T
    Chromosoma; 1996 Oct; 105(4):250-60. PubMed ID: 8854885
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeted homologous recombination at the endogenous adenine phosphoribosyltransferase locus in Chinese hamster cells.
    Adair GM; Nairn RS; Wilson JH; Seidman MM; Brotherman KA; MacKinnon C; Scheerer JB
    Proc Natl Acad Sci U S A; 1989 Jun; 86(12):4574-8. PubMed ID: 2734308
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Altered topoisomerase I activity and recombination activating gene expression in a human leukemia cell line resistant to doxorubicin.
    Riou JF; Grondard L; Petitgenet O; Abitbol M; Lavelle F
    Biochem Pharmacol; 1993 Sep; 46(5):851-61. PubMed ID: 8396937
    [TBL] [Abstract][Full Text] [Related]  

  • 12. International Commission for Protection Against Environmental Mutagens and Carcinogens. Mutagenicity and carcinogenicity of topoisomerase-interactive agents.
    Anderson RD; Berger NA
    Mutat Res; 1994 Aug; 309(1):109-42. PubMed ID: 7519727
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Homologous recombination is a highly conserved determinant of the synergistic cytotoxicity between cisplatin and DNA topoisomerase I poisons.
    van Waardenburg RC; de Jong LA; van Delft F; van Eijndhoven MA; Bohlander M; Bjornsti MA; Brouwer J; Schellens JH
    Mol Cancer Ther; 2004 Apr; 3(4):393-402. PubMed ID: 15078982
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of vector topology on homologous recombination at the CHO aprt locus.
    Ward MA; Abramow-Newerly W; Roder JC
    Somat Cell Mol Genet; 1993 May; 19(3):257-64. PubMed ID: 8332933
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Studies on the role of topoisomerases in general, gene- and strand-specific DNA repair.
    Stevnsner T; Bohr VA
    Carcinogenesis; 1993 Sep; 14(9):1841-50. PubMed ID: 8403208
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The role of the DNA mismatch repair system in the cytotoxicity of the topoisomerase inhibitors camptothecin and etoposide to human colorectal cancer cells.
    Jacob S; Aguado M; Fallik D; Praz F
    Cancer Res; 2001 Sep; 61(17):6555-62. PubMed ID: 11522654
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cytogenetic effects of inhibition of topoisomerase I or II activities in the CHO mutant EM9 and its parental line AA8.
    Cortés F; Piñero J; Palitti F
    Mutat Res; 1993 Aug; 288(2):281-9. PubMed ID: 7688089
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Probing the interaction of the cytotoxic bisdioxopiperazine ICRF-193 with the closed enzyme clamp of human topoisomerase IIalpha.
    Patel S; Jazrawi E; Creighton AM; Austin CA; Fisher LM
    Mol Pharmacol; 2000 Sep; 58(3):560-8. PubMed ID: 10953049
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Genotoxic profile of inhibitors of topoisomerases I (camptothecin) and II (etoposide) in a mitotic recombination and sex-chromosome loss somatic eye assay of Drosophila melanogaster.
    Sortibrán AN; Téllez MG; Rodríguez-Arnaiz R
    Mutat Res; 2006 Apr; 604(1-2):83-90. PubMed ID: 16529987
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Various inhibitors of DNA topoisomerases diminish repair-specific DNA incision in UV-irradiated human fibroblasts.
    Thielmann HW; Popanda O; Gersbach H; Gilberg F
    Carcinogenesis; 1993 Nov; 14(11):2341-51. PubMed ID: 8242865
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.