BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

128 related articles for article (PubMed ID: 8604980)

  • 1. Specific derivatization of the active site tyrosine in dUTPase perturbs ligand binding to the active site.
    Vertessy BG; Persson R; Rosengren AM; Zeppezauer M; Nyman PO
    Biochem Biophys Res Commun; 1996 Feb; 219(2):294-300. PubMed ID: 8604980
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structure of dUTPase from equine infectious anaemia virus; active site metal binding in a substrate analogue complex.
    Dauter Z; Persson R; Rosengren AM; Nyman PO; Wilson KS; Cedergren-Zeppezauer ES
    J Mol Biol; 1999 Jan; 285(2):655-73. PubMed ID: 9878436
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Methylene substitution at the alpha-beta bridging position within the phosphate chain of dUDP profoundly perturbs ligand accommodation into the dUTPase active site.
    Kovári J; Barabás O; Varga B; Békési A; Tölgyesi F; Fidy J; Nagy J; Vértessy BG
    Proteins; 2008 Apr; 71(1):308-19. PubMed ID: 17932923
    [TBL] [Abstract][Full Text] [Related]  

  • 4. dUTPase from the retrovirus equine infectious anemia virus: high-level expression in Escherichia coli and purification.
    Bergman AC; Björnberg O; Nord J; Rosengren AM; Nyman PO
    Protein Expr Purif; 1995 Jun; 6(3):379-87. PubMed ID: 7663176
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of tyrosine as a functional residue in the active site of Escherichia coli dUTPase.
    Vertessy BG; Zalud P; Nyman PO; Zeppezauer M
    Biochim Biophys Acta; 1994 Mar; 1205(1):146-50. PubMed ID: 8142479
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure/function analysis of a dUTPase: catalytic mechanism of a potential chemotherapeutic target.
    Harris JM; McIntosh EM; Muscat GE
    J Mol Biol; 1999 Apr; 288(2):275-87. PubMed ID: 10329142
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Crystal structure of a dUTPase.
    Cedergren-Zeppezauer ES; Larsson G; Nyman PO; Dauter Z; Wilson KS
    Nature; 1992 Feb; 355(6362):740-3. PubMed ID: 1311056
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization and mutational studies of equine infectious anemia virus dUTPase.
    Shao H; Robek MD; Threadgill DS; Mankowski LS; Cameron CE; Fuller FJ; Payne SL
    Biochim Biophys Acta; 1997 May; 1339(2):181-91. PubMed ID: 9187238
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The crystal structure of a complex of Campylobacter jejuni dUTPase with substrate analogue sheds light on the mechanism and suggests the "basic module" for dimeric d(C/U)TPases.
    Moroz OV; Harkiolaki M; Galperin MY; Vagin AA; González-Pacanowska D; Wilson KS
    J Mol Biol; 2004 Oct; 342(5):1583-97. PubMed ID: 15364583
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Flexible glycine rich motif of Escherichia coli deoxyuridine triphosphate nucleotidohydrolase is important for functional but not for structural integrity of the enzyme.
    Vertessy BG
    Proteins; 1997 Aug; 28(4):568-79. PubMed ID: 9261872
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The C-terminus of dUTPase: observation on flexibility using NMR.
    Nord J; Nyman P; Larsson G; Drakenberg T
    FEBS Lett; 2001 Mar; 492(3):228-32. PubMed ID: 11257499
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mechanistic studies of dUTPases.
    Kovári J; Imre T; Szabó P; Vértessy BG
    Nucleosides Nucleotides Nucleic Acids; 2004 Oct; 23(8-9):1475-9. PubMed ID: 15571280
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The monomeric dUTPase from Epstein-Barr virus mimics trimeric dUTPases.
    Tarbouriech N; Buisson M; Seigneurin JM; Cusack S; Burmeister WP
    Structure; 2005 Sep; 13(9):1299-310. PubMed ID: 16154087
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification and function of a shrimp white spot syndrome virus (WSSV) gene that encodes a dUTPase.
    Liu X; Yang F
    Virus Res; 2005 Jun; 110(1-2):21-30. PubMed ID: 15845252
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Altered active site flexibility and a structural metal-binding site in eukaryotic dUTPase: kinetic characterization, folding, and crystallographic studies of the homotrimeric Drosophila enzyme.
    Kovári J; Barabás O; Takács E; Békési A; Dubrovay Z; Pongrácz V; Zagyva I; Imre T; Szabó P; Vértessy BG
    J Biol Chem; 2004 Apr; 279(17):17932-44. PubMed ID: 14724274
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A double role for a strictly conserved serine: further insights into the dUTPase catalytic mechanism.
    Palmén LG; Becker K; Bülow L; Kvassman JO
    Biochemistry; 2008 Jul; 47(30):7863-74. PubMed ID: 18597482
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential inhibition of homotrimeric dUTPases by the 3'-azido derivative of dideoxy-UTP.
    Palmén LG; Kvassman JO
    J Enzyme Inhib Med Chem; 2010 Feb; 25(1):146-50. PubMed ID: 19761402
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Altered subunit communication in subfamilies of trimeric dUTPases.
    Fiser A; Vértessy BG
    Biochem Biophys Res Commun; 2000 Dec; 279(2):534-42. PubMed ID: 11118321
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A consensus sequence for a functional human endogenous retrovirus K (HERV-K) dUTPase.
    Harris JM; Haynes RH; McIntosh EM
    Biochem Cell Biol; 1997; 75(2):143-51. PubMed ID: 9250362
    [TBL] [Abstract][Full Text] [Related]  

  • 20. dUTPase from the retrovirus equine infectious anemia virus: specificity, turnover and inhibition.
    Nord J; Larsson G; Kvassman JO; Rosengren AM; Nyman PO
    FEBS Lett; 1997 Sep; 414(2):271-4. PubMed ID: 9315700
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.