BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

289 related articles for article (PubMed ID: 8605876)

  • 1. Phosphorylated interferon-alpha receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of the 113 kDa STAT2 protein.
    Yan H; Krishnan K; Greenlund AC; Gupta S; Lim JT; Schreiber RD; Schindler CW; Krolewski JJ
    EMBO J; 1996 Mar; 15(5):1064-74. PubMed ID: 8605876
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dimerization of a chimeric CD4-interferon-alpha receptor reconstitutes the signaling events preceding STAT phosphorylation.
    Krishnan K; Yan H; Lim JT; Krolewski JJ
    Oncogene; 1996 Jul; 13(1):125-33. PubMed ID: 8700538
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling.
    Li X; Leung S; Kerr IM; Stark GR
    Mol Cell Biol; 1997 Apr; 17(4):2048-56. PubMed ID: 9121453
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The proximal tyrosines of the cytoplasmic domain of the beta chain of the type I interferon receptor are essential for signal transducer and activator of transcription (Stat) 2 activation. Evidence that two Stat2 sites are required to reach a threshold of interferon alpha-induced Stat2 tyrosine phosphorylation that allows normal formation of interferon-stimulated gene factor 3.
    Nadeau OW; Domanski P; Usacheva A; Uddin S; Platanias LC; Pitha P; Raz R; Levy D; Majchrzak B; Fish E; Colamonici OR
    J Biol Chem; 1999 Feb; 274(7):4045-52. PubMed ID: 9933596
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Direct binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 tyrosine kinase.
    Colamonici O; Yan H; Domanski P; Handa R; Smalley D; Mullersman J; Witte M; Krishnan K; Krolewski J
    Mol Cell Biol; 1994 Dec; 14(12):8133-42. PubMed ID: 7526154
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Stat2 binding to the interferon-alpha receptor 2 subunit is not required for interferon-alpha signaling.
    Nguyen VP; Saleh AZ; Arch AE; Yan H; Piazza F; Kim J; Krolewski JJ
    J Biol Chem; 2002 Mar; 277(12):9713-21. PubMed ID: 11786546
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The antiviral action of interferon is potentiated by removal of the conserved IRTAM domain of the IFNAR1 chain of the interferon alpha/beta receptor: effects on JAK-STAT activation and receptor down-regulation.
    Basu L; Yang CH; Murti A; Garcia JV; Croze E; Constantinescu SN; Mullersman JE; Pfeffer LM
    Virology; 1998 Mar; 242(1):14-21. PubMed ID: 9501047
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Localization of a receptor nonapeptide with a possible role in the binding of the type I interferons.
    Eid P; Langer JA; Bailly G; Lejealle R; Guymarho J; Tovey MG
    Eur Cytokine Netw; 2000 Dec; 11(4):560-73. PubMed ID: 11125298
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Affinity of Stat2 for the subunits of the interferon alpha receptor.
    Saleh AZ; Nguyen VP; Krolewski JJ
    Biochemistry; 2002 Sep; 41(37):11261-8. PubMed ID: 12220192
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of amino acid residues critical for the Src-homology 2 domain-dependent docking of Stat2 to the interferon alpha receptor.
    Krishnan K; Singh B; Krolewski JJ
    J Biol Chem; 1998 Jul; 273(31):19495-501. PubMed ID: 9677371
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN-alpha signals.
    Gupta S; Yan H; Wong LH; Ralph S; Krolewski J; Schindler C
    EMBO J; 1996 Mar; 15(5):1075-84. PubMed ID: 8605877
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular characterization of an alpha interferon receptor 1 subunit (IFNaR1) domain required for TYK2 binding and signal transduction.
    Yan H; Krishnan K; Lim JT; Contillo LG; Krolewski JJ
    Mol Cell Biol; 1996 May; 16(5):2074-82. PubMed ID: 8628273
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The neutralization of type I IFN biologic actions by anti-IFNAR-2 monoclonal antibodies is not entirely due to inhibition of Jak-Stat tyrosine phosphorylation.
    Novick D; Nabioullin RR; Ragsdale W; McKenna S; Weiser W; Garone L; Burkins C; Kim SH; Rubinstein M; Tepper MA; Arulanandam AR
    J Interferon Cytokine Res; 2000 Nov; 20(11):971-82. PubMed ID: 11096454
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Arginine/lysine-rich structural element is involved in interferon-induced nuclear import of STATs.
    Melen K; Kinnunen L; Julkunen I
    J Biol Chem; 2001 May; 276(19):16447-55. PubMed ID: 11150296
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The human papilloma virus (HPV)-18 E6 oncoprotein physically associates with Tyk2 and impairs Jak-STAT activation by interferon-alpha.
    Li S; Labrecque S; Gauzzi MC; Cuddihy AR; Wong AH; Pellegrini S; Matlashewski GJ; Koromilas AE
    Oncogene; 1999 Oct; 18(42):5727-37. PubMed ID: 10523853
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathway.
    You M; Yu DH; Feng GS
    Mol Cell Biol; 1999 Mar; 19(3):2416-24. PubMed ID: 10022928
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Direct signal transduction via functional interferon-alphabeta receptors in CD34+ hematopoietic stem cells.
    Giron-Michel J; Weill D; Bailly G; Legras S; Nardeux PC; Azzarone B; Tovey MG; Eid P
    Leukemia; 2002 Jun; 16(6):1135-42. PubMed ID: 12040445
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Constitutive STAT1 tyrosine phosphorylation in U937 monocytes overexpressing the TYK2 protein tyrosine kinase does not induce gene transcription.
    Eilers A; Kanda K; Klose B; Krolewski J; Decker T
    Cell Growth Differ; 1996 Jun; 7(6):833-40. PubMed ID: 8780896
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Function of Stat2 protein in transcriptional activation by alpha interferon.
    Qureshi SA; Leung S; Kerr IM; Stark GR; Darnell JE
    Mol Cell Biol; 1996 Jan; 16(1):288-93. PubMed ID: 8524306
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Distinct mechanisms of STAT phosphorylation via the interferon-alpha/beta receptor. Selective inhibition of STAT3 and STAT5 by piceatannol.
    Su L; David M
    J Biol Chem; 2000 Apr; 275(17):12661-6. PubMed ID: 10777558
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.